First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity حسب Julian Loureiro (20357035)

"…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…"

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity حسب Julian Loureiro (20357035)

"…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…"

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity حسب Julian Loureiro (20357035)

"…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…"

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity حسب Julian Loureiro (20357035)

"…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…"

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity حسب Julian Loureiro (20357035)

"…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…"

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity حسب Julian Loureiro (20357035)

"…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…"

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity حسب Julian Loureiro (20357035)

"…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…"

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity حسب Julian Loureiro (20357035)

"…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…"

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity حسب Julian Loureiro (20357035)

"…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…"

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity حسب Julian Loureiro (20357035)

"…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…"

Figure 3 from A Cost-Effective Two-Step Approach for Multi-Cancer Early Detection in High-Risk Populations حسب Shuaipeng Geng (20612220)

"…<p>Outcome of the two-step MCED approach in the case–control study. In the case–control cohort, the two-step MCED approach significantly improved specificity from 91.0% to 99.3%, whereas sensitivity decreased from 49.9% to 39.9%. …"

Characterization of systolic pulmonary arterial pressure (sPAP) of WT BMP9 in rats. حسب Tobias G. Schips (21799838)

الموضوعات:

Pharmacological characterization of WT BMP9 and A347E variant <i>in vitro</i> and <i>in vivo.</i> حسب Tobias G. Schips (21799838)

الموضوعات:

Summary of cell-based assay EC50 results for WT BMP9 and A347E variant. حسب Tobias G. Schips (21799838)

الموضوعات:

Evaluation of chronic <i>in vivo</i> efficacy in 21 days rat MCT model in prevention mode. حسب Tobias G. Schips (21799838)

الموضوعات:

Hemodynamic effects of WT BMP9 in rats. حسب Tobias G. Schips (21799838)

الموضوعات:

Evaluation of chronic <i>in vivo</i> efficacy in 21 days rat MCT model in prevention mode. حسب Tobias G. Schips (21799838)

الموضوعات:

<i>In vivo</i> PK evaluation of WT BMP9 in naïve SD rats. حسب Tobias G. Schips (21799838)

الموضوعات:

Pharmacological characterization of WT BMP9 and A347E variant <i>in vitro</i> and <i>in vivo.</i> حسب Tobias G. Schips (21799838)

الموضوعات:

Characterization of safety pharmacology of WT BMP9 in rats. حسب Tobias G. Schips (21799838)

الموضوعات: