Evaluation of refined cement-based matrix systems for extrusion of wood fiber cement by Nassar, Roz-Ud-Din

“…Test results show that most of the additives lowered the bulk specific gravity but increased the moisture absorption capacity of extruded fiber cement products when compared with the basic mix formulation. Generally, the additives caused drop in flexural strength but did not significantly affect the flexural toughness of the matrix formulations. …”
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Coping mechanisms among Lebanese first-time college students by Doumit, Rita

“…Strategies xiv used varied with the type of situation. A greater proportion of overall strategies used included active and internal coping strategies which were focused on resolving the issue or problem. …”
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Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response by Noura Al-Zeheimi (5177066)

“…From a panel of tested proteins and genes, we found that the levels of plasma NRP-1, placenta growth factor (PlGF) and immune cell expression of the transcription factor <i>SNAI1</i> before and after NAC were significantly different. …”

Modulation of SLFN11 induces changes in DNA Damage response in breast cancer by Christophe Michel Raynaud (17449906)

“…The use of a CRISPR-dCas9 UNISAM and KRAB system could increase or decrease SLFN11 expression significantly (up to fivefold), stably and specifically in BT-549 and T47D cancer cell lines. …”

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies by Fawaz E., Alanazi

“…VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway by Olfa Khalifa (10914452)

“…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …”

Effect of phosphorus supplementation on weight gain and waist circumference of overweight/obese adults by Bassil, MS

“…Several parameters of subjective appetite scores were decreased in the phosphorus-supplemented group. Conclusions: Phosphorus supplementation for 12 weeks significantly decreases body weight, BMI, waist circumference and subjective appetite scores. …”
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Clinical correlates of white-matter abnormalities on head magnetic resonance imaging by Dimassi, Hani

“…The children with white-matter abnormalities and decreased tone had significantly less signal intensity abnormality than the other study groups. …”
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Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases by Glazer, Evan

“…We hypothesized that PET uptake levels were artificially decreased after chemotherapy. That is, lesions that appeared to be nonmalignant were actually viable malignant lesions.…”
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Epidemiology of injuries from fire, heat and hot substances: global, regional and national morbidity and mortality estimates from the Global Burden of Disease 2017 study by Spencer L James (8673927)

Masked phenomenon: renal and cardiovascular complications; review and updates by Elmukhtar Habas (14777677)

“…The masked phenomenon (MP) (MHTN and MUHTN) increases susceptibility to end-organ damage (a two-fold greater risk for cardiovascular events and kidney dysfunction). …”

Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer by Sampath, Lakshmi

“…Results: (DTPA)n-trastuzumab-(IRDye800)m showed significantly greater binding to SKBr3 cells than to MDA-MB-231 cells. …”
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Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation by Mai S., El-Shoukrofy

“…Compound 2a activated PPARγ with an EC50 value of 3.4 μM in a Gal4-hybrid reporter gene assay, indicating partial agonistic action. …”
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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) by Varghese P. Inchakalody (14557382)

“…Bisulfite-sequencing demonstrated 45.6% demethylation efficiency at the NY-ESO-1 gene promoter region and RT-qPCR analysis confirmed the significant induction of NY-ESO-1 at mRNA level (128-fold increase, *p < 0.050). …”

Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro by Najem, Sonia A.

“…Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …”
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A Decision Support Tool for Smart Campus Applications – An AUS Case Study by Khatri, Mohamed Faisal

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Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation by Mai S. El-Shoukrofy (19646815)

“…Compound 2a activated PPARγ with an EC₅₀ value of 3.4 μM in a Gal4-hybrid reporter gene assay, indicating partial agonistic action. …”

The Islamist groups in Tripoli. (c2008) by Abbas, Nivine H.

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Investigating the Role of Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2) in Inflammatory Bowel Disease: Expression in Clinical Samples and Insights from In Vitro Models by Mezher, Nawal

“…Using Caco-2 and HT-29 intestinal epithelial cell lines stimulated with Tumor Necrosis Factor-α (TNF-α) or Dextran Sodium Sulfate (DSS) as in vitro models of inflammation, we observed upregulation of ACSS2 protein expression. ACSS2 inhibition significantly reduced the expression of pro-inflammatory cytokines such as Interleukin 8 (IL-8), IL-1β, and TNF-α, and attenuated activation of NF-κB and MAPK signaling pathways, as evidenced by decreased phosphorylation of p65 and ERK/MEK. …”
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STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration by Ayat S. Hammad (9592374)

“…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …”