يعرض 41 - 60 نتائج من 5,003 نتيجة بحث عن '(( significant cause basic ) OR ( significant ((side decrease) OR (teer decrease)) ))', وقت الاستعلام: 0.37s تنقيح النتائج
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    Prodrug Strategy to Address Impaired Oral Absorption of a Weakly Basic TYK2 Inhibitor Caused by a Gastric Acid-Reducing Agent حسب Murugaiah A M Subbaiah (20289384)

    منشور في 2024
    "…The pH-dependent solubility of the weakly basic TYK2 inhibitor <b>1</b> posed a risk to its advancement, given that drugs with such profiles have exhibited drug–drug interaction (DDI) with stomach acid-reducing agents in humans. …"
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    Inotodiol decreases clone formation in HCC cells. حسب Yushuang Xing (20636685)

    منشور في 2025
    "…Chemicals and chemotherapeutic agents have been experiencing problems such as side effects and drug resistance in the treatment of HCC, which cannot meet the needs of clinical treatment. …"
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    Inclusion of TPP side chains result in decreased melanoma cell mitochondria membrane potential, oxygen consumption, and increased DHE oxidation. حسب Kyle C. Kloepping (9928265)

    منشور في 2020
    "…Further, there is a structure-activity relationship between TPP side chain length and metabolic disruption; with inclusion of longer side chains resulting in the greatest decreases in mitochondria membrane potential and DHE oxidation.…"
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