Showing 41 - 60 results of 38,537 for search '(( significant cause basic ) OR ( significant ((side decrease) OR (we decrease)) ))', query time: 2.25s Refine Results
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    Prodrug Strategy to Address Impaired Oral Absorption of a Weakly Basic TYK2 Inhibitor Caused by a Gastric Acid-Reducing Agent by Murugaiah A M Subbaiah (20289384)

    Published 2024
    “…The pH-dependent solubility of the weakly basic TYK2 inhibitor <b>1</b> posed a risk to its advancement, given that drugs with such profiles have exhibited drug–drug interaction (DDI) with stomach acid-reducing agents in humans. …”
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    Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

    Published 2025
    “…Chemicals and chemotherapeutic agents have been experiencing problems such as side effects and drug resistance in the treatment of HCC, which cannot meet the needs of clinical treatment. …”
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    The effect of amiloride in decreasing albuminuria in patients with diabetic kidney diseases: a prospective, crossover, open-label study by Ruizhao Li (417128)

    Published 2021
    “…</p> <p>In summary, among patients with DKD, amiloride could decrease albuminuria without severe side effects, which was accompanied by the significant decline of urinary suPAR.…”
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    Inclusion of TPP side chains result in decreased melanoma cell mitochondria membrane potential, oxygen consumption, and increased DHE oxidation. by Kyle C. Kloepping (9928265)

    Published 2020
    “…Further, there is a structure-activity relationship between TPP side chain length and metabolic disruption; with inclusion of longer side chains resulting in the greatest decreases in mitochondria membrane potential and DHE oxidation.…”