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    Prodrug Strategy to Address Impaired Oral Absorption of a Weakly Basic TYK2 Inhibitor Caused by a Gastric Acid-Reducing Agent by Murugaiah A M Subbaiah (20289384)

    Published 2024
    “…The pH-dependent solubility of the weakly basic TYK2 inhibitor <b>1</b> posed a risk to its advancement, given that drugs with such profiles have exhibited drug–drug interaction (DDI) with stomach acid-reducing agents in humans. …”
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