Search alternatives:
significant cause » significant change (Expand Search), significant changes (Expand Search), significant gap (Expand Search)
linear decrease » linear increase (Expand Search)
larger decrease » marked decrease (Expand Search)
significant cause » significant change (Expand Search), significant changes (Expand Search), significant gap (Expand Search)
linear decrease » linear increase (Expand Search)
larger decrease » marked decrease (Expand Search)
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Prodrug Strategy to Address Impaired Oral Absorption of a Weakly Basic TYK2 Inhibitor Caused by a Gastric Acid-Reducing Agent
Published 2024“…The pH-dependent solubility of the weakly basic TYK2 inhibitor <b>1</b> posed a risk to its advancement, given that drugs with such profiles have exhibited drug–drug interaction (DDI) with stomach acid-reducing agents in humans. …”
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Scheme of g-λ model with larger values λ.
Published 2024“…The findings suggest that when λ is respectively equal to 4.19, 8.57, 10, and 12.15, the peak particle velocity (PPV) of the transmitted waves is significantly close to the incident wave amplitude. Furthermore, when λ is fixed, the energy transmission coefficient increases with the incident wave amplitude but decreases with the incident wave frequency. …”
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