Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... by Mohamed Yassin (4166515)

“…<p>This systematic review aims to summarise the clinical outcomes of l-glutamine, crizanlizumab, and voxelotor in the treatment of sickle cell disease (SCD) based on clinical trials and real-world data and to identify any gaps in the observations. …”

The utility of a deep learning-based approach in Her-2/neu assessment in breast cancer by Saidul Kabir (15302407)

“…<p>Introduction HER-2/neu is a protein present on the surface of specific cancer cells and has been linked to the development and progression of certain cancer types. …”

The utility of a deep learning-based approach in Her-2/neu assessment in breast cancer by Saidul, Kabir

“…IntroductionHER-2/neu is a protein present on the surface of specific cancer cells and has been linked to the development and progression of certain cancer types. …”
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Synergistic Effects of Nanomedicine Targeting TNFR2 and DNA Demethylation Inhibitor—An Opportunity for Cancer Treatment by Mohammad A. I. Al-Hatamleh (11564929)

“…<p dir="ltr">Tumor necrosis factor receptor 2 (TNFR2) is expressed on some tumor cells, such as myeloma, Hodgkin lymphoma, colon cancer and ovarian cancer, as well as immunosuppressive cells. …”

The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer by El Mais, Nour

“…Finally, we looked at the effect of HuArgI (Co)-PEG5000 on 3D motility of the ovarian cancer cell line, using a collagen based assay. …”
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MicroRNA-3148 acts as molecular switch promoting malignant transformation and adipocytic differentiation of immortalized human bone marrow stromal cells via direct targeting of the... by Radhakrishnan Vishnubalaji (3563306)

“…Concordantly, global gene expression profiling revealed significant enrichment in cholesterol biosynthesis pathway, and pathways related to enhanced cell movement and survival, whereas processes related to bone and connective tissue developments, cell death, apoptosis, and necrosis were downregulated. …”

Harnessing piperine for enhanced antimicrobial activity of carbon dot‑modified cellulose fibers by Ravindran, Sreeshna

“…The antibacterial properties of the CDs were tested on cellulose discs, demonstrating strong adherence and significant inhibition of bacterial cells. The cytotoxicity studies showed that these CDs, at concentrations up to 0.1 mg/mL, and the CD-modified fibers are benign to mammalian cells, emphasizing their safety for human use. …”
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“Effectiveness of Text Messaging Intervention on Intuitive Eating by Manana, Batoul

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Antiamoebic activity of plant‑based natural products and their conjugated silver nanoparticles against Acanthamoeba castellanii (ATCC 50492) by Anwar, Areeba

“…Interestingly, these compounds and nanoconjugates did not exhibit in vitro cytotoxic effects against human cells. Plant-based compounds and extracts could be an interesting strategy in development of alternative therapeutics against Acanthamoeba infections.…”
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Conceptual Design and Analysis of Concentrated Photovoltaic Thermal (CPVT) Solar Collectors with Different Configurations by Sharaf, Omar Z.

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Mathematical Model-Based Optimization of Continuous Flow Photobioreactor Operating at Steady State Using MATLAB Optimization Function by Ibrahim M. Abu-Reesh (4501213)

“…The obtained results are of technological significance for processes such as CO₂-fixation and biofuel production. …”

Fault Diagnosis Based Machine Learning and Fault Tolerant Control of Multicellular Converter Used in Photovoltaic Water Pumping System by B. Rouabah (17947820)

“…<p dir="ltr">Currently, providing water in developing countries, especially in dry and hot rural areas, is a significant challenge. However, creating new electric grids is often expensive. …”

Light chain amyloidosis presenting with autoimmune hepatitis-primary sclerosing cholangitis overlap syndrome by Hammad Shabir Chaudhry (20376378)

“…Her liver enzymes (Alkaline phosphatase, Alanine aminotransferase, Aspartate aminotransferase had decreased significantly.</p><h3>Conclusions</h3><p dir="ltr">AL amyloidosis can very rarely present as AIH-PSC overlap syndrome, manifesting with raised liver enzymes, biliary strictures, pruritis and positive liver antibodies. …”

Selective ROCK Inhibitor Enhances Blood Flow Recovery after Hindlimb Ischemia by Hend Salah Fayed (17732622)

Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways by William J. Young (18426897)

“…In contrast for QRS, connective tissue components and processes for cell growth and extracellular matrix interactions are significantly enriched. …”

Immunoprofile of childhood diabetes by Meritxell Espino-Guarch (15430868)

“…</p> <p>Objective: Based on next-generation tools we investigated the transcriptomics differences between Treg and Tcon cells and correlated these with the inflammatory proteins and metabolites present during the development of insulin resistance and T2D.…”

Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer by Sampath, Lakshmi

“…Results: (DTPA)n-trastuzumab-(IRDye800)m showed significantly greater binding to SKBr3 cells than to MDA-MB-231 cells. …”
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Date palm (Phoenix dactylifera L.) fruit's polyphenols as potential inhibitors for human amylin fibril formation and toxicity in type 2 diabetes by Ali Chaari (827168)

“…</p><h3>Method</h3><p dir="ltr">In this study, we used a broad biophysical approach, using cell biology techniques and bioinformatic tools, to demonstrate that various polyphenols from date palm (<i>Phoenix dactylifera</i> L.) fruit significantly inhibited hIAPP aggregation and cytotoxicity.…”

Structure-activity relationships of copper-based metal-organic Frameworks: Investigating antibacterial mechanisms against gram-positive and gram-negative bacteria by Muhammad Hubab (20639153)

“…<u>Transmission Electron Microscopy</u> (TEM) analysis verified the significant <u>biocidal</u> activity of Cu-MOFs against both the Gram-negative (<i><u>Escherichia coli</u></i>) and Gram-positive (<u>Staphylococcus aureus</u> and <i>Bacillus subtilis</i>) bacteria, by disrupting their cell membranes and inducing cell death primarily through Cu²⁺ <u>ion release</u>. …”

Structure-Activity Relationships of Copper-Based Metal-Organic Frameworks: Investigating Antibacterial Mechanisms against Gram-Positive and Gram-Negative Bacteria by Muhammad Hubab (20639153)

“…Transmission Electron Microscopy (TEM) analysis verified the significant biocidal activity of Cu-MOFs against both the Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus and Bacillus subtilis) bacteria, by disrupting their cell membranes and inducing cell death primarily through Cu²⁺ ion release. …”