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141
Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy
منشور في 2020"…Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …"
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masterThesis -
142
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
منشور في 2022"…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …"
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143
EEG-Based Semantic Vigilance Level Classification Using Directed Connectivity Patterns and Graph Theory Analysis
منشور في 2020"…The strength and directionality of information flow in the connectivity network by RWTE/PDC and the GTA measures significantly decrease with vigilance decrement, p<0.05. …"
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article -
144
Turkronicles: diachronic resources for the fast evolving Turkish language
منشور في 2025"…Regarding writing conventions, we found a noticeable decrease in the use of circumflex. …"
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145
Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
منشور في 2022"…These knockout zebrafish displayed significant morphological heart alterations related to a significant decrease in ventricular and atrial diameters at systolic and diastolic states at the larval stages. …"
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146
Endocrine contribution to the sexual dysfunction in patients with advanced chronic kidney disease and the role of hyperprolactinemia
منشور في 2021"…Patients treated with cabergoline (<i>n</i> = 26) showed a significant increase in LH levels (<i>p</i> = .003) and a significant decrease in prolactin levels (<i>p</i> = .003). …"
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147
Dissecting the signaling pathways regulating the vascular endothelial growth factor (VEGF) in brain tumor cells. (c2017)
منشور في 2017"…However, when both RhoA and RhoC were knocked down, VEGF expression decreased after EGF stimulation. Moreover, when the astrocytoma cells were subjected to hypoxia at different times, we detected a significant increase in pERK. …"
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masterThesis -
148
Towards secure private and trustworthy human-centric embedded machine learning: An emotion-aware facial recognition case study
منشور في 2023"…We find that input quantization partially degrades the efficacy of adversarial and backdoor attacks at the cost of a slight decrease in accuracy over clean inputs. …"
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149
Geopolitical instability and environmental sustainability
منشور في 2025"…Geopolitical instability significantly impacts environmental sustainability, yet its role remains underexplored. …"
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article -
150
STARD 13 in prostate cancer. (c2018)
منشور في 2018"…Knocking down StarD13 by siRNA led to an increase in cell proliferation and adhesion yet a decrease in cell motility and cell speed in prostate cancer. …"
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masterThesis -
151
Reduction of laboratory utilization in the intensive care unit
منشور في 2016"…We only allowed the G3+I-STAT (arterial blood gas only) cartridges in the MICU in hopes of decreasing duplicative laboratory test results. …"
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article -
152
Rescue cerclage
منشور في 2006"…CONCLUSION: In contrast to previously reported series, our results show that rescue cerclage can result in significant pregnancy prolongation. Outcomes are not as grim as prior literature suggests, and we strongly support the consideration of rescue cerclage for these patients.…"
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article -
153
Privacy-Preserving Fog Aggregation of Smart Grid Data Using Dynamic Differentially-Private Data Perturbation
منشور في 2022"…However, billing accuracy can be degraded by using such additive noise techniques. We propose a differentially-private model that perturbs data by adding noise obtained from a virtual chargeable battery, while maintaining billing accuracy. …"
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154
Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of RhoGTPases in cleft/lip palate development
منشور في 2021"…Our results showed that there is no difference in viability of the VWS patient cells compared to healthy control cells. However, a significant decrease in the migratory and adhesion ability of the VWS patient cells was detected compared to the control, which could account for the phenotype. …"
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masterThesis -
155
Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
منشور في 2017"…We assess the effects of stretch rate on the mechanical properties of Prolene® (Ethicon, Gynecare, Somerville, NJ, USA), a knitted polypropylene mesh. …"
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conferenceObject -
156
Walking around the preferred speed: examination of metabolic, perceptual, spatiotemporal and stability parameters
منشور في 2024"…While metabolic, perceptual and spatiotemporal values were sensitive to the smallest change in speed (i.e., 0.5 km·h<sup>−1)</sup>, a significant increase in the rate of carbohydrate oxidation and decrease in % fat oxidation were only observed at speeds above PWS. …"
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157
Studies on anti-colon cancer potential of nanoformulations of curcumin and succinylated curcumin in mannosylated chitosan
منشور في 2023"…A significant induction of early and late apoptosis in the CUR-NPs and CUR.SA-NPs treated CRC cell lines compared to untreated cells was observed. …"
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article -
158
Deep Learning in LncRNAome: Contribution, Challenges, and Perspectives
منشور في 2020"…The abundance of lncRNAs and their diverse roles across cell types have opened numerous avenues for the research community regarding lncRNAome. …"
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159
The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach
منشور في 2020"…This study aimed to identify upregulated genes and significant pathways involved in CLBC. The SUM159 cell line is derived from human CLBC tissue; the GSE50697 dataset contains three replicates of SUM159 cells treated with pBabe puro miR-203 and three replicates of control SUM159 cells (pBabe puro). …"
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article -
160
Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent
منشور في 2019"…[HuArgI (Co)-PEG5000]-induced arginine deprivation led to extensive and prolonged activation of autophagy, which proved to be deleterious to cell survival since its inhibition led to a significant decrease in cytotoxicity. This indicates that the activation of autophagy following arginine-deprivation, rather than being protective, mediates cell cytotoxicity leading to death by autophagy.…"
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article