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larger decrease » marked decrease (Expand Search)
challenge » challenges (Expand Search)
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6421
Image 2_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc...
Published 2025“…Background<p>Renal fibrosis, characterized by the abnormal accumulation of extracellular matrix in renal tissue and progressive loss of kidney function, is posing a significant challenge in clinical treatment. While several therapeutic options exist, effective treatments remain limited. …”
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6422
Table 2_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.docx
Published 2025“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”
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6423
Table 1_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx
Published 2025“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”
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6424
Table 1_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc...
Published 2025“…Background<p>Renal fibrosis, characterized by the abnormal accumulation of extracellular matrix in renal tissue and progressive loss of kidney function, is posing a significant challenge in clinical treatment. While several therapeutic options exist, effective treatments remain limited. …”
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6425
Table 3_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx
Published 2025“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”
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6426
DataSheet1_Exploring the naturally acquired response to Pvs47 gametocyte antigen.docx
Published 2024“…<p>Malaria represents a challenging global public health task, with Plasmodium vivax being the predominant parasite in Brazil and the most widely distributed species throughout the world. …”
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6427
Ambulatory modeling of vocal hyperfunction (Parra et al., 2025)
Published 2025“…A categorical approach assessed the relationship between different values of DPI and changes in estimated physiological parameters.</p><p dir="ltr"><b>Results: </b>Results showed significant differences between the PVH and control groups in key parameters, including statistical moments of H1–H2, SPL, PS, and muscle activity of lateral cricoarytenoid (LCA) and cricothyroid (CT) muscles. …”
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6428
<b>Antiretroviral therapy </b><b>does not correct the dysregulations of plasma virome and cytokines induced by HIV-1</b>
Published 2024“…Increased abundance and prevalence of HPgV-1 were further confirmed by RT-qPCR assay in a larger cohort of 114. Notably, most cytokines dysregulated were not fully restored by ART, with abnormal levels of IL-10, GM-CSF, VEGF, and eotaxin, and a significantly increased level of plasma I-FABP. …”
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6429
<b>Antiretroviral therapy</b><b> does not correct the dysregulations of plasma virome and cytokines induced by HIV-1</b>
Published 2024“…Increased abundance and prevalence of HPgV-1 were further confirmed by RT-qPCR assay in a larger cohort of 114. Notably, most cytokines dysregulated were not fully restored by ART, with abnormal levels of IL-10, GM-CSF, VEGF, and eotaxin, and a significantly increased level of plasma I-FABP. …”
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6430
Video 1_Nanotopographic control of actin waves and growth cone navigation in developing neurons.avi
Published 2025“…We find that actin-wave speeds do not change significantly in the first 2 weeks of neurite development on flat substrates, but decrease over the same period in neurites on nanoridges. …”
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6431
Data Sheet 1_Nanotopographic control of actin waves and growth cone navigation in developing neurons.pdf
Published 2025“…We find that actin-wave speeds do not change significantly in the first 2 weeks of neurite development on flat substrates, but decrease over the same period in neurites on nanoridges. …”
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6432
Video 2_Nanotopographic control of actin waves and growth cone navigation in developing neurons.avi
Published 2025“…We find that actin-wave speeds do not change significantly in the first 2 weeks of neurite development on flat substrates, but decrease over the same period in neurites on nanoridges. …”
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6433
Table 1_Nanotopographic control of actin waves and growth cone navigation in developing neurons.xlsx
Published 2025“…We find that actin-wave speeds do not change significantly in the first 2 weeks of neurite development on flat substrates, but decrease over the same period in neurites on nanoridges. …”
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6434
Data Sheet 5_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv
Published 2025“…High SDI regions saw significant declines in DALY rates (−4.75% annually), while Low SDI regions experienced negligible change (0.01%). …”
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6435
Data Sheet 1_Effects of methylphenidate on children with attention deficit hyperactivity disorder: a study using clinical and multimodal approaches including go/no-go task and func...
Published 2025“…Concurrently, they showed significantly increased accuracy on both go and no-go trials, along with significantly decreased reaction times on go trials. …”
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6436
Table 1_Association of oxidative balance score with metabolic syndrome and its components in middle-aged and older individuals in the United States.docx
Published 2025“…Background<p>The prevalence of metabolic syndrome (MetS) among middle-aged and older individuals in the U.S. is rising, posing significant mortality risks. Diet is a key factor in MetS development, yet few studies have examined the combined effects of dietary and lifestyle factors on MetS in this group. …”
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6437
Data Sheet 4_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv
Published 2025“…High SDI regions saw significant declines in DALY rates (−4.75% annually), while Low SDI regions experienced negligible change (0.01%). …”
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6438
Data Sheet 2_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv
Published 2025“…High SDI regions saw significant declines in DALY rates (−4.75% annually), while Low SDI regions experienced negligible change (0.01%). …”
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6439
Data Sheet 3_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv
Published 2025“…High SDI regions saw significant declines in DALY rates (−4.75% annually), while Low SDI regions experienced negligible change (0.01%). …”
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6440
Data Sheet 7_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv
Published 2025“…High SDI regions saw significant declines in DALY rates (−4.75% annually), while Low SDI regions experienced negligible change (0.01%). …”