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changes decrease » larger decrease (Expand Search), change increases (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
challenge » challenges (Expand Search)
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5781
Table 1_Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway.docx
Published 2024“…MiR-936 overexpression and GV102-Pim-3-shRNA significantly attenuated the activity of the ANKRD18A/Src/NRF2 pathway to decrease the expression of Ankyrin repeat domain-containing protein 18A (ANKRD18A), Src, and Nuclear factor (erythroid-derived 2)-like 2 (NRF2), especially decreasing NRF2 nuclear retention and transcriptional activity. …”
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5782
Image 3_Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway.jpeg
Published 2024“…MiR-936 overexpression and GV102-Pim-3-shRNA significantly attenuated the activity of the ANKRD18A/Src/NRF2 pathway to decrease the expression of Ankyrin repeat domain-containing protein 18A (ANKRD18A), Src, and Nuclear factor (erythroid-derived 2)-like 2 (NRF2), especially decreasing NRF2 nuclear retention and transcriptional activity. …”
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5783
Image 1_The gut microbiota in liver transplantation recipients during the perioperative and postoperative recovery period.png
Published 2025“…Metagenomic sequencing, analyzed using the LEfSe method, identified a total of 50 genera that played significant roles in this process. The changes in microbiota exhibited the same trend as the 16S rRNA results. …”
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5784
Image 2_The gut microbiota in liver transplantation recipients during the perioperative and postoperative recovery period.jpeg
Published 2025“…Metagenomic sequencing, analyzed using the LEfSe method, identified a total of 50 genera that played significant roles in this process. The changes in microbiota exhibited the same trend as the 16S rRNA results. …”
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5785
Related to Fig 3.
Published 2025“…(<b>O</b>, <b>P</b>) Cell proliferation assay confirms an increase in cell proliferation of BT-474_ZFX<sup>OE</sup> cells (mean ± SEM, <i>n</i> = 5) (O), whereas BT-474_ZFX<sup>SL</sup> cells (mean ± SEM, <i>n</i> = 3) show decreased cell proliferation (P). (<b>Q</b>) Tumor growth kinetics recorded a significantly higher growth of BT-474_ZFX<sup>OE</sup> (mean ± SEM, <i>n</i> = 5) than BT-474_VECT<sup>OE</sup> tumors. …”
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5786
Table 1_GRHL2-HER3 and E-cadherin mediate EGFR-bypass drug resistance in lung cancer cells.xlsx
Published 2025“…However, resistance to EGFR inhibitors, such as erlotinib, presents a significant challenge in treating lung cancer. In this study, we established an EGFR-independent, erlotinib-resistant (ER) phenotype in lung cancer A549 cells by exposing them to erlotinib for an extended period. …”
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5787
Data Sheet 1_GRHL2-HER3 and E-cadherin mediate EGFR-bypass drug resistance in lung cancer cells.pdf
Published 2025“…However, resistance to EGFR inhibitors, such as erlotinib, presents a significant challenge in treating lung cancer. In this study, we established an EGFR-independent, erlotinib-resistant (ER) phenotype in lung cancer A549 cells by exposing them to erlotinib for an extended period. …”
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5788
DataSheet1_The effect of 12-week high-dose Colostrum Bovinum supplementation on immunological, hematological and biochemical markers in endurance athletes: a randomized crossover p...
Published 2024“…Furthermore, after COL supplementation decrease of hematocrit at REC (p<0.05) was revealed.…”
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5789
Data_Sheet_1_Effects of household solid fuel use on sarcopenia in middle-aged and older adults: evidence from a nationwide cohort study.docx
Published 2024“…Switching to clean cooking fuels significantly reduced sarcopenia risk (HR 0.766, 95% CI 0.599–0.979). …”
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5790
Image 2_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels based o...
Published 2025“…Joinpoint regression models quantified temporal trends through Annual Percent Change (APC) and Average Annual Percent Change (AAPC).…”
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5791
Data Sheet 1_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels ba...
Published 2025“…Joinpoint regression models quantified temporal trends through Annual Percent Change (APC) and Average Annual Percent Change (AAPC).…”
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5792
Image 1_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels based o...
Published 2025“…Joinpoint regression models quantified temporal trends through Annual Percent Change (APC) and Average Annual Percent Change (AAPC).…”
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5793
Image 3_Dietary risk factors and cancer mortality burden from 1990 to 2021: a comparative study of China and global regions with varying sociodemographic development levels based o...
Published 2025“…Joinpoint regression models quantified temporal trends through Annual Percent Change (APC) and Average Annual Percent Change (AAPC).…”
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5794
Short-Ranged United-Atom Model for Efficient Simulations of Glycerol and Its Aqueous Mixtures
Published 2025“…Capturing its structural and thermodynamic properties in liquid and glass states remains challenging due to discrepancies between NMR, neutron scattering experiments, and all-atom (AA) simulations. …”
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5795
Table 1_Impact of removing laver (Porphyra) farming racks on the distribution, diversity and foraging behavior of waterbirds in coastal wetlands in eastern China.xlsx
Published 2025“…Notably, the numbers of ducks, plovers, and sandpipers increased significantly, while gull numbers decreased significantly, likely due to habitat structure loss. (3) The proportion of foraging behaviors of 4 common waterbird species increased significantly after restoration, while the percentage of resting behavior significantly decreased. (4) No significant differences in macrobenthos species richness, abundance, biomass or α-diversity indices were detected post-restoration, but the macrobenthos in laver racks area (lower tidal zone) were significantly more abundant than those in the non-racks area (middle tidal zone).…”
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5796
Data Sheet 1_The expression regulation of recA gene and bacterial class 2 integron-associated genes induced by antibiotics.xlsx
Published 2025“…Induced strains exhibited increased resistance to the drugs, with the most significant changes observed in the clinical isolates, particularly concerning CIP resistance. …”
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5797
Table 2_The expression regulation of recA gene and bacterial class 2 integron-associated genes induced by antibiotics.xlsx
Published 2025“…Induced strains exhibited increased resistance to the drugs, with the most significant changes observed in the clinical isolates, particularly concerning CIP resistance. …”
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5798
Table 1_Ultrasonographic assessment of optic nerve sheath diameter on the affected and unaffected sides as a predictor of clinical deterioration at discharge in patients with large...
Published 2025“…Longitudinal changes in bilateral ONSD showed remarkable overlap in both individual and group observations. …”
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5799
Discriminatory learning preferentially enhances reward associated input.
Published 2025“…(E) Fraction of glomeruli with significant changes post learning. Yellow: increased, dark grey: decreased, light grey: unchanged. …”
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5800
Data Sheet 1_Increased accrual of diverse patient populations in oncology phase I clinical trials at the University of Colorado Cancer Center.docx
Published 2025“…However, in the most common cancer type, colorectal cancer, higher ADI scores were associated with decreased median PFS and OS.</p>Conclusion<p>The interventions resulted in an increase in accrual of non-English speaking patients, however, there was not yet a significant change in overall race and ethnicity. …”