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challenge » challenges (Expand Search)
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6001
Image 1_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.tif
Published 2025“…N-telopeptide (NTX) showed no significant change.</p>Conclusions<p>Vitamin K2 supplementation improves key bone turnover biomarkers, particularly OC and ucOC. …”
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6002
Table 1_Global, regional, and national burden of liver cancer in adolescents and young adults from 1990 to 2021: an analysis of the global burden of disease study 2021 and forecast...
Published 2025“…East Asia bears the highest burden, with males experiencing significantly higher rates than females. The burden increases with age, peaking at 35–39 years. …”
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6003
Table 1_A daily positive work reflection intervention for psychological distress among Chinese nurses: a pilot randomized controlled trial.docx
Published 2025“…</p>Conclusions<p>Results suggest that a daily positive work reflection intervention is a feasible and promising intervention for decreasing Chinese nurses' psychological distress. The study used a convenience sample which led to a concern of external generalizability, and the study had limited evaluation of long-term change.…”
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6004
Table 1_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.docx
Published 2025“…N-telopeptide (NTX) showed no significant change.</p>Conclusions<p>Vitamin K2 supplementation improves key bone turnover biomarkers, particularly OC and ucOC. …”
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6005
Data Sheet 2_Gut microbiota metabolite acetate mediates free fatty acid receptor 2 expression to alleviate atopic dermatitis.zip
Published 2025“…Acetate supplementation in AD mice significantly ameliorated 2,4-dinitrobenzene (DNCB)-induced dermatitis, as evidenced by reduced skin lesion severity, lower dermatitis scores, and decreased epidermal thickening. …”
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6006
Data Sheet 2_Improved early postoperative cognition in elderly gastrointestinal patients: a randomized controlled trial on the role of ultrasound-guided stellate ganglion block.doc
Published 2025“…Both groups showed significant changes in IL-6, SOD and MDA levels, when compared to preoperative values. …”
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6007
Data Sheet 1_Improved early postoperative cognition in elderly gastrointestinal patients: a randomized controlled trial on the role of ultrasound-guided stellate ganglion block.doc...
Published 2025“…Both groups showed significant changes in IL-6, SOD and MDA levels, when compared to preoperative values. …”
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6008
Data Sheet 1_Gut microbiota metabolite acetate mediates free fatty acid receptor 2 expression to alleviate atopic dermatitis.zip
Published 2025“…Acetate supplementation in AD mice significantly ameliorated 2,4-dinitrobenzene (DNCB)-induced dermatitis, as evidenced by reduced skin lesion severity, lower dermatitis scores, and decreased epidermal thickening. …”
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6009
Image 4_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.tif
Published 2025“…N-telopeptide (NTX) showed no significant change.</p>Conclusions<p>Vitamin K2 supplementation improves key bone turnover biomarkers, particularly OC and ucOC. …”
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6010
Image 2_The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis.tif
Published 2025“…N-telopeptide (NTX) showed no significant change.</p>Conclusions<p>Vitamin K2 supplementation improves key bone turnover biomarkers, particularly OC and ucOC. …”
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6011
Table 1_Cytokine dynamics in the blood and cerebrospinal fluid of HIV/AIDS patients with cryptococcal meningitis receiving antifungal therapy.docx
Published 2025“…Over 28 days of antifungal treatment, significant decreases in the CSF levels of IL-2 and IL-10 and the plasma levels of IL-10 and IL-4 were observed. …”
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6012
Data Sheet 1_Comparative analysis of proteomics and transcriptomics reveals novel mechanism underlying the antibacterial activity and immune-enhancing properties of horse milk.zip
Published 2025“…Further transcriptome analysis demonstrated that PGL exerted significant transcriptional changes to bacteria. Enrichment analysis showed PGL could inhibit growth of P. aeruginosa and E. coli by repressing the biosynthesis of secondary metabolites.…”
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6013
Table 1_Long-term multicomponent exercise enhances functional mobility in early-stage Parkinson’s disease: a 48-month retrospective cohort study.docx
Published 2025“…VO<sub>2</sub>peak (−1.1 mL·kg<sup>−1</sup>·min<sup>−1</sup>; p = 0.142) and muscle mass (−0.7 kg; p = 0.068) showed no significant changes. VO<sub>2</sub>peak was the sole independent predictor of functional performance at baseline and follow-up, while muscle mass had limited explanatory value. …”
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6014
Impact of COVID-19 on early intervention referrals (Zellner et al., 2025)
Published 2025“…<p dir="ltr"><b>Purpose: </b>We sought to examine changes in national Part C early intervention (EI) service provision associated with the onset of the COVID-19 pandemic. …”
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6015
Data Sheet 1_Global, regional, and national burdens of endometriosis from 1990 to 2021: a trend analysis.docx
Published 2025“…Background<p>Endometriosis is a common, chronic, estrogen-dependent gynecological disorder that significantly affects patients’ quality of life. However, the disease burden and its trends may be undergoing significant changes, and comprehensive data on this issue are currently lacking. …”
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6016
Data Sheet 1_White matter functional networks in the developing brain.docx
Published 2024“…Additionally, 8-year-olds showed a greater distribution of brain activity energy in the high-frequency range of 0.01–0.15 Hz. Significant developmental differences in brain white matter functional networks exist between the two group, characterized by increased inter-network FC, decreased intra-network FC, and higher high-frequency energy distribution. …”
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6017
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6018
Table 6_Global burden of low back pain attributable to smoking in 204 countries and territories in 1990–2021.xlsx
Published 2025“…Finally, it is forecasted that the smoking-related LBP burden will decrease from 2022 to 2036.</p>Conclusion<p>From 1990 to 2021, the global ASDR of LBP attributable to smoking decreased, and this downward trend is expected to persist. …”
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6019
Table 4_Global burden of low back pain attributable to smoking in 204 countries and territories in 1990–2021.xlsx
Published 2025“…Finally, it is forecasted that the smoking-related LBP burden will decrease from 2022 to 2036.</p>Conclusion<p>From 1990 to 2021, the global ASDR of LBP attributable to smoking decreased, and this downward trend is expected to persist. …”
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6020
Table 5_Global burden of low back pain attributable to smoking in 204 countries and territories in 1990–2021.xlsx
Published 2025“…Finally, it is forecasted that the smoking-related LBP burden will decrease from 2022 to 2036.</p>Conclusion<p>From 1990 to 2021, the global ASDR of LBP attributable to smoking decreased, and this downward trend is expected to persist. …”