Showing 6,201 - 6,220 results of 8,227 for search '(( significant challenge decrease ) OR ( significant ((changes decrease) OR (largest decrease)) ))', query time: 0.44s Refine Results
  1. 6201

    Image 1_Multi-omics analysis reveals indicator features of microbe-host interactions during Candida albicans colonization and subsequent infection.tif by Huan Zhang (220065)

    Published 2024
    “…</p>Importance<p>Candida albicans invasive infections pose a significant challenge to contemporary medicine, with mortality rates from such fungal infections remaining high despite antifungal treatment. …”
  2. 6202

    Baseline firing rate: locomotion speed control and the effect of behavioral context on negative preferring neurons. by Yun Wen Chu (20968520)

    Published 2025
    “…(<b>E</b>) Bar graph of the percent of neurons that significantly increase, decrease, or do not change during the Miss or Away condition. …”
  3. 6203

    Data Sheet 6_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip by Haiyan Liao (6100043)

    Published 2025
    “…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”
  4. 6204

    Data Sheet 1_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.docx by Haiyan Liao (6100043)

    Published 2025
    “…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”
  5. 6205

    Data Sheet 7_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip by Haiyan Liao (6100043)

    Published 2025
    “…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”
  6. 6206

    Data Sheet 3_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip by Haiyan Liao (6100043)

    Published 2025
    “…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”
  7. 6207

    Table 1_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.xlsx by Haiyan Liao (6100043)

    Published 2025
    “…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”
  8. 6208

    Data Sheet 2_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip by Haiyan Liao (6100043)

    Published 2025
    “…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”
  9. 6209

    Image 1_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.tif by Haiyan Liao (6100043)

    Published 2025
    “…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”
  10. 6210

    Data Sheet 4_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip by Haiyan Liao (6100043)

    Published 2025
    “…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”
  11. 6211

    Data Sheet 5_Mechanistic study of the hsa_circ_0074158 binding EIF4A3 impairing sepsis-induced endothelial barrier.zip by Haiyan Liao (6100043)

    Published 2025
    “…</p>Results<p>In both LPS-treated human umbilical vein endothelial cells (HUVECs) and cecal ligation and puncture (CLP) murine models, the overexpression of hsa_circ_0074158 (the mouse homolog of hsa_circ_0074158 is named circ_Ctnna1) significantly decreased CTNNA1 mRNA stability and increased endothelial hyperpermeability, while its knockdown restored barrier integrity. …”
  12. 6212

    <b>Optimizing Viable Bacteria Detection in Ballast Tank Sediments: Addressing PCR Inhibitors and Relic DNA</b> by 1 Anonymous (21812990)

    Published 2025
    “…This study tackles two key challenges in viable microorganism monitoring in ballast tank sediments: interference from PCR inhibitors and the persistence of relic DNA. …”
  13. 6213

    Data Sheet 1_Dietary supplementation with hydroxy-methionine manganese improves meat quality, antioxidant capacity, and lipid metabolism in Cherry Valley ducks (Anas platyrhynchos... by Yang Liu (4829)

    Published 2025
    “…Serum high-density lipoprotein cholesterol levels increased significantly in the MnHMet groups compared to the 0 mg/kg group and showed a quadratic change to increasing MnHMet levels (P < 0.05). …”
  14. 6214

    Table 2_Integrated metabolomics and gut microbiota analysis to explore the potential mechanism of levo-tetrahydropalmatine against ketamine addiction.xlsx by Yan Du (229593)

    Published 2025
    “…Introduction<p>Metabolic and gut microbiota (GM) disturbance play a significant role in the complex pathogenesis of substance dependence. …”
  15. 6215

    Image 2_Endocrine-disrupting effects of environmental BPS and PFOS on human brain organoid development.tiff by Andrea Di Credico (13137135)

    Published 2025
    “…PFOS exposure coincided with decreased transthyretin expression, suggesting a potential influence on thyroid hormone availability.…”
  16. 6216

    Data Sheet 1_Frustration and its impact on search and rescue canines.pdf by Sally Dickinson (254872)

    Published 2025
    “…Our results revealed significant decreases in heart rate variability following frustration and increased latency in the search task, suggesting that frustration had a more pronounced impact on the dogs' physiological state and performance compared to exercise. …”
  17. 6217

    Data Sheet 1_Response mechanisms of Polygonatum kingianum to temperature stress: implications for cultivation practices.pdf by Huali Qian (11711225)

    Published 2025
    “…In response to oxidative damage, the activities of superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT), as well as the levels of non-enzymatic antioxidants (ascorbate/ASA and glutathione/GSH), were significantly upregulated. Transcriptome analysis further revealed that these physiological changes are regulated by multiple stress-related pathways, mainly including phenylpropanoid biosynthesis, glycolysis/gluconeogenesis, starch and sucrose metabolism, and plant hormone signaling. …”
  18. 6218

    Table 1_Integrated metabolomics and gut microbiota analysis to explore the potential mechanism of levo-tetrahydropalmatine against ketamine addiction.xlsx by Yan Du (229593)

    Published 2025
    “…Introduction<p>Metabolic and gut microbiota (GM) disturbance play a significant role in the complex pathogenesis of substance dependence. …”
  19. 6219

    Image 1_Endocrine-disrupting effects of environmental BPS and PFOS on human brain organoid development.tiff by Andrea Di Credico (13137135)

    Published 2025
    “…PFOS exposure coincided with decreased transthyretin expression, suggesting a potential influence on thyroid hormone availability.…”
  20. 6220

    Table 6_UV-C and hydration state drive pulsed light-induced proteome damage in Bacillus pumilus spores.xlsx by Imed Dorbani (21031028)

    Published 2025
    “…</p>Results<p>PL treatment induced a significantly greater proteomic alteration compared to UV-C, particularly in spores suspended in water, where the number of proteins with decreased abundance was ~6-fold higher than in spores sprayed on a polystyrene surface. …”