يعرض 20,441 - 20,460 نتائج من 21,342 نتيجة بحث عن '(( significant challenge decrease ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.43s تنقيح النتائج
  1. 20441

    Image 1_Delineation of single-cell Altas provides new insights for development of coronary artery lesions in Kawasaki disease: bad and good signaling molecules.tif حسب Qiuping Lin (3091146)

    منشور في 2025
    "…In the monocytes of CAL patients, MCH-II is a significantly increased signal and RESISTIN is a significantly decreased signal compared to non-CAL counterpart.…"
  2. 20442

    Image_1_Effects of clear corneal incision location and morphology on corneal surgically induced astigmatism and higher-order aberrations after ICL V4c implantation.JPEG حسب Jun Wang (5906)

    منشور في 2024
    "…Anterior corneal SIA was significantly correlated to Dis-En and Dis-Ex in the superior CCI group. …"
  3. 20443

    Data Sheet 2_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for... حسب Shen Tian (4424170)

    منشور في 2025
    "…Key risk factors included behavioral and metabolic factors, among which a diet low in whole grains significantly increased CRC incidence.</p>Conclusion<p>From 1990 to 2021, the global CRC burden increased significantly, with notable variations across SDI regions. …"
  4. 20444

    Image 1_Temporal left ventricular ejection fraction variations and outcomes in wide population of cardiovascular patients with and without heart failure.tif حسب Radosław Szczerba (20837081)

    منشور في 2025
    "…In patients with HF, Kaplan–Meier survival curves showed significantly lower MACCE occurrence in HFimpEF and stable LVEF than in decreased LVEF (11.46%/year vs. 12.5%/year vs. 21.6%/year; log-rank p = 0.199 and p < 0.001) and HFimpEF constituted one of independent predictors of MACCE (HR = 0.84, 95% CI: 0.76–0.93). …"
  5. 20445

    Image 1_Effectiveness of Mindfulness and Qigong Training for Self-Healing in patients with Hwabyung and depressive disorder: a randomized controlled trial.tif حسب Seok-In Yoon (13879160)

    منشور في 2025
    "…</p>Results<p>MQT-SH significantly decreased Hwabyung, depression, anxiety, and anger while increasing subjective vitality, and the effectiveness of the intervention were maintained at a short-term follow-up of 6 weeks. …"
  6. 20446

    Table 2_Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance.docx حسب Wenjing Xue (2880686)

    منشور في 2025
    "…GO and KEGG analyses indicated that QgYp significantly affects TGF-β signaling pathway. In addition, the results of qPCR and Western blot analysis from both in vitro and in vivo experiments indicated that QgYp significantly downregulated the expression of proteins and mRNA associated with the TGF-β1/Smad2/3 pathway. …"
  7. 20447

    Data Sheet 12_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip... حسب Chutian Zhang (10732350)

    منشور في 2025
    "…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca<sup>2+</sup> fluorescence intensity and the expression of the IP<sub>3</sub>R-VDAC-MCU complex in MPP<sup>+</sup>-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"
  8. 20448

    Data Sheet 2_Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance.pdf حسب Wenjing Xue (2880686)

    منشور في 2025
    "…GO and KEGG analyses indicated that QgYp significantly affects TGF-β signaling pathway. In addition, the results of qPCR and Western blot analysis from both in vitro and in vivo experiments indicated that QgYp significantly downregulated the expression of proteins and mRNA associated with the TGF-β1/Smad2/3 pathway. …"
  9. 20449

    Supplementary Material for: Does oXiris Matter? A Comparative Outcome Study in CRRT-Treated Septic ICU Patients حسب figshare admin karger (2628495)

    منشور في 2025
    "…Inflammatory markers (CRP, PCT) remained elevated in oXiris patients through day 5, while hemodynamic stabilization (lactate decline, norepinephrine reduction) was more pronounced. Platelet counts decreased in both groups without recovery. Conclusions: Our study demonstrated that patients with sepsis treated using the oXiris filter exhibited significantly higher ICU survival rates, despite higher mechanical ventilation duration and ICU length of stay. …"
  10. 20450

    Image 4_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif حسب Toru Miwa (8528715)

    منشور في 2025
    "…Auditory brainstem response (ABR) thresholds were significantly elevated, and distortion-product otoacoustic emissions (DPOAE) indicated outer hair cell dysfunction. …"
  11. 20451

    Data Sheet 4_Causality of genetically determined serum metabolites on lower back pain or/and sciatica: a comprehensive Mendelian randomized study.pdf حسب Yi-Ming Ren (555968)

    منشور في 2024
    "…Among them, 8 serum metabolites decreased risk of sciatica or/and lower back pain significantly (P < 0.05), and 14 serum metabolites increased risk of sciatica or/and lower back pain significantly (P < 0.05). …"
  12. 20452

    Table 1_Relationship between high-density lipoprotein cholesterol levels and nutritional risk screening-assessment-intervention: a multicenter cross-sectional study.pdf حسب Qian Li (114642)

    منشور في 2025
    "…Additionally, patients with nausea and vomiting, pancreatic insufficiency, severe infection, fever, and hypoalbuminemia decreased HDL-C levels by 0.156 mmol/L, 1.465 mmol/L, 0.403 mmol/L, 0.301 mmol/L, and 0.250 mmol/L, respectively. …"
  13. 20453

    Data Sheet 1_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.pdf حسب Chutian Zhang (10732350)

    منشور في 2025
    "…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca<sup>2+</sup> fluorescence intensity and the expression of the IP<sub>3</sub>R-VDAC-MCU complex in MPP<sup>+</sup>-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"
  14. 20454

    Data Sheet 1_Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis.xlsx حسب Xiaodong Wang (66801)

    منشور في 2024
    "…The experimental results showed that β-sitosterol could significantly inhibit the excessive proliferation of MH7A cells (p< 0.05). …"
  15. 20455

    Table 3_Interactions between the intestinal microbiome and host genes in regulating vibriosis resistance in Cynoglossus semilaevis.xlsx حسب Weiwei Zheng (140828)

    منشور في 2025
    "…</p>Results<p>Obvious histopathological differences were observed between the resistant and susceptible groups in terms of inflammatory cells infiltration, and tissue dissociation of mucosal layer. 16S rRNA sequencing analysis indicated that Vibrio increased but Stenotrophomonas, Chryseobacterium, Delftia, and Salinivibrio decreased in the susceptible group. Compared to the control group, 1,986 differentially expressed genes (DEGs) were detected in the susceptible group, significantly more than the 310 DEGs found in the resistant group. …"
  16. 20456

    Table_1_Effects of clear corneal incision location and morphology on corneal surgically induced astigmatism and higher-order aberrations after ICL V4c implantation.DOCX حسب Jun Wang (5906)

    منشور في 2024
    "…Anterior corneal SIA was significantly correlated to Dis-En and Dis-Ex in the superior CCI group. …"
  17. 20457

    Table_2_Effects of clear corneal incision location and morphology on corneal surgically induced astigmatism and higher-order aberrations after ICL V4c implantation.DOCX حسب Jun Wang (5906)

    منشور في 2024
    "…Anterior corneal SIA was significantly correlated to Dis-En and Dis-Ex in the superior CCI group. …"
  18. 20458

    Image 2_Modulation of the hepatic RANK-RANKL-OPG axis by combined C5 and CD14 inhibition in a long-term polytrauma model.jpeg حسب Yang Li (7082)

    منشور في 2024
    "…Compared to the Nail group, AST serum concentrations were significantly decreased in the Nail+Therapy group after 72 h (p<0.05). …"
  19. 20459

    Image 1_Modulation of the hepatic RANK-RANKL-OPG axis by combined C5 and CD14 inhibition in a long-term polytrauma model.jpeg حسب Yang Li (7082)

    منشور في 2024
    "…Compared to the Nail group, AST serum concentrations were significantly decreased in the Nail+Therapy group after 72 h (p<0.05). …"
  20. 20460

    Table 1_Effects of perinatal nutrition supplementation and early weaning on serum biochemistry, metabolomics, and reproduction in yaks.docx حسب Kaiyuan Shang (20453966)

    منشور في 2024
    "…Lipid transportation molecules apolipoprotein B100 and very low-density lipoprotein of SF and SW yaks were significantly increased along with the decreased lipid mobilization products non-esterified fatty acid and β-hydroxybutyric acid when compared to GF yaks at −15 and 30 d. …"