يعرض 17,981 - 18,000 نتائج من 21,342 نتيجة بحث عن '(( significant challenge decrease ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.58s تنقيح النتائج
  1. 17981

    Ybx1 regulation of its target mRNAs is m<sup>5</sup>C-depdendent (Related to Fig 5). حسب Jian Zhang (1682)

    منشور في 2025
    "…<p><b>(A)</b> RT-qPCR confirmed the decreased expression levels of Ybx1 target mRNAs in neural stem cells with Ybx1 knockdown using siRNA. …"
  2. 17982

    Table 1_COVID-19 pandemic increased ESKAPEEc bloodstream infections and amplified carbapenem resistance in Chinese children: a multicenter surveillance study (2016–2023).xls حسب Xiaoqiang Li (612879)

    منشور في 2025
    "…Between 2016–2019 and 2020–2023, resistance to ceftazidime and gentamicin decreased in Escherichia coli and Klebsiella pneumoniae while resistance to imipenem and meropenem increased. …"
  3. 17983

    Table2_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx حسب Yifang He (18126257)

    منشور في 2024
    "…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…"
  4. 17984

    Table13_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx حسب Yifang He (18126257)

    منشور في 2024
    "…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…"
  5. 17985

    Data Sheet 1_Perceived benefits and barriers to the use of long-acting injectable antiretroviral treatment among adolescents and young people living with HIV in Western Kenya: qual... حسب Shukri A. Hassan (14245301)

    منشور في 2025
    "…Introduction<p>Adolescents and young people living with HIV (AYPLHIV) face significant hurdles in adhering to daily oral antiretroviral therapy (ART). …"
  6. 17986

    Table 2_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.docx حسب Leqing Zhou (20981021)

    منشور في 2025
    "…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…"
  7. 17987

    Table12_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx حسب Yifang He (18126257)

    منشور في 2024
    "…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…"
  8. 17988

    Data Sheet 2_Perceived benefits and barriers to the use of long-acting injectable antiretroviral treatment among adolescents and young people living with HIV in Western Kenya: qual... حسب Shukri A. Hassan (14245301)

    منشور في 2025
    "…Introduction<p>Adolescents and young people living with HIV (AYPLHIV) face significant hurdles in adhering to daily oral antiretroviral therapy (ART). …"
  9. 17989

    Table3_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx حسب Yifang He (18126257)

    منشور في 2024
    "…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…"
  10. 17990

    Table9_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx حسب Yifang He (18126257)

    منشور في 2024
    "…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…"
  11. 17991

    Image1_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.tif حسب Yifang He (18126257)

    منشور في 2024
    "…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…"
  12. 17992

    Table7_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx حسب Yifang He (18126257)

    منشور في 2024
    "…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…"
  13. 17993

    DataSheet_1_FCGR2/3 polymorphisms are associated with susceptibility to Kawasaki disease but do not predict intravenous immunoglobulin resistance and coronary artery aneurysms.docx حسب Paula Uittenbogaard (19691794)

    منشور في 2024
    "…Treatment with intravenous immunoglobulin (IVIg) significantly decreases the risk of CAA, possibly through competitive binding to Fc-gamma receptors (FcγRs), which reduces the binding of pathological immune complexes. …"
  14. 17994
  15. 17995

    Table6_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx حسب Yifang He (18126257)

    منشور في 2024
    "…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…"
  16. 17996

    Image 3_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif حسب Leqing Zhou (20981021)

    منشور في 2025
    "…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m<sup>2</sup>, while it decreased by 11.4ml/min/1.73 m<sup>2</sup> in the RNU group (WMD, 11.81 ml/min/1.73 m<sup>2</sup>; 95%CI,9.06-14.56; P<0.0001).…"
  17. 17997
  18. 17998

    Data Sheet 1_Unilateral biportal endoscopic transforaminal lumbar interbody fusion versus minimally invasive transforaminal lumbar interbody fusion for single-level lumbar spondylo... حسب Yu Zhang (12946)

    منشور في 2025
    "…Compared with MIS-TLIF, ULIF demonstrated significantly reduced intraoperative blood loss [WMD = −35.71, 95% CI (−51.80, −19.63), p < 0.01], fewer intraoperative fluoroscopy times [WMD = −1.29, 95% CI (−2.56, −0.02), p < 0.05], lower postoperative drainage volume [WMD = −20.64, 95% CI (−37.13, −4.15), p = 0.01], shorter postoperative ambulation time [WMD = −0.30, 95% CI (−0.42, −0.17), p < 0.01], and decreased hospital stay duration [WMD = −1.50, 95% CI (−2.09, −0.90), p < 0.01]. …"
  19. 17999
  20. 18000

    Table 1_Targeting nail psoriasis: IL-17A inhibitors demonstrate site-specific superiority over IL-23 inhibitor in a 24-week dermoscopy-guided real-world cohort.docx حسب Xiamei Yan (21014921)

    منشور في 2025
    "…</p>Results<p>(1) By week 24, PASI, BSA, DLQI and NAPSI scores had significantly decreased from baseline in all groups (P<0.001). (2) By week 24: SEC, IXE, and GUS groups saw nail matrix NAPSI score improvements of 65.9%, 60.5%, and 51.5%, with 68%, 55%, and 30% achieving NAPSI 60; Nail bed NAPSI score improvements were 58.8%, 68.6%, and 65.8%, with 28%, 65%, and 40% achieving NAPSI 60; Total NAPSI score improvements were 62.7%, 64.6%, and 53.7%, with 44%, 70%, and 30% achieving NAPSI 60. (3) All patients in the SEC and IXE groups achieved PASI 75, compared to 85% in the GUS group. …"