Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation by Mai S., El-Shoukrofy

“…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound 2a. …”
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Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies by Umar Nawaz Kayani (17131781)

“…<p dir="ltr">Maintaining a stable exchange rate is a challenging task for the world, especially for developing economies. …”

The promise of tirzepatide: A narrative review of metabolic benefits by Sara Sokary (17337724)

“…<p>Obesity and type 2 diabetes mellites (T2DM) are intertwined epidemics that continue to pose significant challenges to global public health. We aim to review the available evidence on the metabolic effects of tirzepatide, focusing on weight loss and maintenance of lost weight, body composition alterations, appetite regulation, glycemic control, and lipid profile modulation. …”

The Impact of Different Urban Configurations on Outdoor Thermal Comfort: A Case Study of the Military Camps in Abu Dhabi, UAE by Ahmed, Amal Mohamed

“…One of the major challenges facing the urban planning sector is the rapid pace of growth of the world‘s urban populations. …”
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Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort by Mohamed Adil Shah Khoodoruth (14589828)

“…<p dir="ltr">Schizophrenia presents significant diagnostic and treatment challenges, particularly in distinguishing between treatment-resistant (TRS) and non-treatment-resistant schizophrenia (NTRS). …”

A component analysis of positive behaviour support plans by Grey, Ian

“…Results There was a significant reduction in the frequency, management difficulty, and episodic severity of challenging behaviour over the duration of the study. …”
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Analysis of The Lebanese Driver's Behavior at The Onset of Yellow Lights at Signalized Intersections by Chahine, Ricardo

“…Intersections are critical points within the highway system at which the risk of crashes increases. This study seeks to better understand the behavior of the Lebanese driver at an intersection by examining the relationship between his/her decisions and psychological attributes. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma by Abou-Ghazal, Mohamed

“…Upon rechallenge, in the animal group that had received WP1066 via o.g., the median survival was 18 days (95% CI: 17, NA), which was significantly different compared to naïve animals challenged at the same time that had a median survival of 11 days (95% CI; 10, NA) (p<0.001); however, there were only 10% long-term survivors suggesting that treatment alone did not generate significant long-term protective immunity. …”
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Unsustainability in emergent systems by Haddad, Marc

“…These challenges are already significant enough to seriously hamper the network's ability to deliver an acceptable level of service within reasonable norms for environmental, health and safety impacts, especially in and around the country's major urban centers. …”
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Road deaths and injuries in India: Action required on the five pillars of road safety by Gopalakrishna Gururaj (19807233)

“…The economic losses from road crashes are estimated to be 3% of GDP and are increasing from year to year (2). …”

A Qualitative Investigation of University Students’ Experience of the Beirut Port Explosion by Issa, Elio

“…We hypothesized that these compounded challenges would have significant psychological implications on emerging adults, including university students, already vulnerable to life’s transitions involving self-discovery and independence. …”
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TCAD Simulation and Analysis of Selective Buried Oxide MOSFET Dynamic Power by Mahmoud, Rana

“…Although the silicon-on-insulator (SOI) MOSFET was introduced to resolve these limitations, other challenges were introduced including the kink effect in the current-voltage characteristics. …”
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Efficient multi-objective neural architecture search framework via policy gradient algorithm by Bo Lyu (16522643)

“…While the multi-objective NAS research addresses these challenges, the individual training required for each candidate architecture demands significant computational resources. …”

Phase II National Study: Job Satisfaction and Workplace Environment Among Community Pharmacists in Lebanon: Pre and Post Economic Crisis by Salaheddin, Amira Talaat

“…In Lebanon, pharmacists face unique challenges stemming from an ongoing economic crisis, the COVID-19 pandemic, and a shifting healthcare landscape. …”
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Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta... by Mohammed M. Al-Humaiqani (18325554)

“…<p dir="ltr">The frequency and severity of climate change are projected to increase, leading to more disasters, increased built environment system (BES) vulnerability, and decreased coping capacity. Achieving resilience objectives in the built environment is challenging and requires the collaboration of all relevant sectors and professionals. …”

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death by Tohme, Sara

“…Acute Myeloid Leukemia (AML) poses significant challenges due to its unfavorable prognosis and limited treatment options, particularly in elderly patients. …”
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Exploring Unique Physiological and Genetic Features of Desert-dwelling Legumes by Madhurima Chatterjee (5331215)

“…Unfortunately, despite having significant beneficial and commercial properties, research initiatives associated with desert legumes are somewhat neglected. …”

Nurse-Led System-wide Unit-based Hospital Acquired Pressure Injury (HAPI) Reduction Project by Mariam Al-Mutawa (18505317)

“…Medical devices contribute to approximately 50% of these total HAPI. HAPI is a significant patient safety issue in hospitalized patients and can lead to increased healthcare costs and a decreased quality of life for patients . …”

Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation by Mai S. El-Shoukrofy (19646815)

“…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound <b>2a</b>. …”

Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems by Local Burden of Disease HIV Collaborators (13279180)

“…This paucity is partially due to incomplete vital registration (VR) systems and statistical challenges related to estimating mortality rates in areas with low numbers of HIV deaths. …”