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يعرض 1 - 20 نتائج من 1,055 نتيجة بحث عن '(( significant challenges based ) OR ( significant ((small decrease) OR (a decrease)) ))', وقت الاستعلام: 0.13s تنقيح النتائج
  1. 1

    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells حسب Nihal AlMuraikhi (6002234)

    منشور في 2019
    "…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
  2. 2

    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

    منشور في 2024
    "…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …"
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    Exploring the Significance of Publication-Age-Based Parameters for Evaluating Researcher Impact حسب Ghulam Mustafa (458105)

    منشور في 2023
    "…In addition, these indices are often evaluated using dissimilar datasets, making it challenging to accurately compare their contributions and significance. …"
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    Feeder protection challenges with high penetration of inverter based distributed generation حسب Margossian, Haraj

    منشور في 2013
    "…The increasing proportion of inverter based distributed generation (DG) in the power system may limit the short circuit power available at distribution substations and consequently cause significant troubles for the protection of distribution feeders where DG are connected. …"
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  8. 8

    Significance of Avicennia Marina in the Arabian Gulf Environment: A Review حسب Kaiprath Puthiyapurayil Haseeba (21392966)

    منشور في 2025
    "…This review addresses the current knowledge gap by providing an overview of Avicennia marina distribution in the Gulf, exploring the significance of its ecosystem services, analyzing the impacts of stressors, and examining conservation and restoration efforts, with attention to nature-based and biotechnological approaches for promoting mangrove growth and conservation in the Gulf.…"
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    Microalgal-based desalination brine remediation: Achievements, challenges, and future research trends حسب Isra E. Gilani (17019066)

    منشور في 2024
    "…In addition, desalination plants consume significant amounts of energy, which contribute to carbon emissions and global warming. …"
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    The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... حسب Wesal Habbab (17346961)

    منشور في 2019
    "…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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    A comprehensive review on harvesting of microalgae using Polyacrylamide-Based Flocculants: Potentials and challenges حسب Shifa M.R. Shaikh (17128882)

    منشور في 2021
    "…Existing pilot-scale and large-scale polyacrylamide-based flocculation studies were explored. The review further identifies the research gaps, key challenges and future prospects for optimizing microalgae flocculation studies.…"
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    Hemodynamics of small aneurysm pairs at the internal carotid artery حسب Jou, Liang-Der

    منشور في 2012
    "…The maximum wall shear stress increases for serial aneurysms, but decreases for parallel aneurysms. Interaction between parallel aneurysms is not significant; however, the proximal aneurysm in serial aneurysms may be subject to a greater rupture risk.…"
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    article
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    QFD-based optimization model for mitigating sustainable supply chain management adoption challenges for Bangladeshi RMG industries حسب Md Al Amin (17808299)

    منشور في 2024
    "…While previous studies often relied on single techniques, this research proposes a novel AHP integrated QFD-based MILP optimization model. This innovative approach empowers Bangladeshi RMG industries to make data-driven decisions for prioritizing <u>sustainability</u> challenges and selecting cost-effective mitigation strategies to promote the integration of sustainability initiatives within the sector. …"
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

    منشور في 2022
    "…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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    Deep random vector functional link transformer network with multiple output layers for significant wave height forecasting حسب Aryan Bhambu (18767731)

    منشور في 2025
    "…<p>Accurate control of wave energy devices relies heavily on precise forecasts of wave heights, yet the dynamic and fluctuating nature of historical wave data presents significant challenges to achieving this precision. …"