بدائل البحث:
significant challenges » significant challenge (توسيع البحث), significant changes (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
challenges case » challenges pose (توسيع البحث), challenges raised (توسيع البحث), challenges faced (توسيع البحث)
significant challenges » significant challenge (توسيع البحث), significant changes (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
challenges case » challenges pose (توسيع البحث), challenges raised (توسيع البحث), challenges faced (توسيع البحث)
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19521
Data Sheet 1_How vanadium and manganese compounds impact cardiac mitochondrial function.pdf
منشور في 2025"…</p>Results and Discussion<p>Both vanadium and manganese salts decreased rates of mitochondrial respiration in a concentration dependent manner, which was attenuated when the metals were complexed to an organic ligand. …"
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19522
Table 4_Analyze agricultural efficiency and influencing factors base on the three-stage DEA model and Malmquist index.xlsx
منشور في 2025"…TFP peaks at 1.157 (increased by 15.7%) in 2019 and declines to 0.978 (decreased by 2.2%) from 2020 to 2021 due to global economic slowdowns. …"
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19523
Data Sheet 1_An alternative structured weight management protocol to rapid weight loss in mixed martial arts: a prospective interventional study of pre-competition weight managemen...
منشور في 2025"…Starting 7 days before the weigh-in, athletes consumed 7 liters of fluids per day, with intake gradually decreasing. On the day before the weigh-in, they consumed only 0.5 liters. …"
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19524
Table 2_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa...
منشور في 2025"…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …"
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19525
Data Sheet 3_Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized cont...
منشور في 2025"…Adding TXL to WM showed a non-significant trend toward reducing myocardial infarction [RR 0.34, 95% CI (0.05, 2.12); NNT = 41] and sudden cardiac death [RR 0.34, 95% CI (0.01, 8.28); NNT = 65]. …"
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19526
Table 1_Outcomes of mini-monovision with monofocal, enhanced monofocal and extended depth-of-focus intraocular lenses.docx
منشور في 2025"…</p>Conclusion<p>While enhanced monofocal and EDOF IOLs may provide slightly better binocular intermediate visual outcomes and higher spectacle independence compared to monofocal lenses with regards to mini-monovision and intermediate vision performance, the differences are not statistically significant. All three IOL types exhibit high patient satisfaction rates when choosing a mini-monovision approach with decreased dependence on spectacles.…"
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19527
CRISPR/Cas9-mediated editing of barley lipoxygenase genes promotes grain fatty acid accumulation and storability
منشور في 2025"…Compared to the wild-type, all mutants displayed normal plant height, tiller number, and grain size, although the <i>loxC1</i> and <i>loxAloxC1</i> mutants exhibited significantly lower thousand grain weights. Notably, the total LOX activity in mature grains decreased by 36–42% in <i>loxC1</i> mutants and by 94% in <i>loxAloxC1</i> mutants, with no significant change observed in <i>loxB</i> mutants. …"
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19528
Supplementary Material for: The efficacy of hemoperfusion in severe COVID-19 patients: A systematic review and meta-analysis
منشور في 2025"…There was no statistically significant difference in mortality between the hemoperfusion and the control groups (RR 0.81 95%CI[0.71, 0.93]; p = 0.15 > 0.05; I2 = 68.2%). …"
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19529
Image 2_Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner.jpeg
منشور في 2025"…No statistically significant differences were observed in pulmonary mechanics between male mice with or without conditional loss of epithelial cell Bdnf, although treatment effects of IL-13 were noted. …"
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19530
Data Sheet 4_Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized cont...
منشور في 2025"…Adding TXL to WM showed a non-significant trend toward reducing myocardial infarction [RR 0.34, 95% CI (0.05, 2.12); NNT = 41] and sudden cardiac death [RR 0.34, 95% CI (0.01, 8.28); NNT = 65]. …"
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19531
Baseline characteristics of the study population.
منشور في 2025"…Widespread use of the measles vaccine has decreased measles antibody potency in the United States plasma supply. …"
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19532
Table3_Use of non-specific immunoglobulins in Catalonia in three third-level hospitals: a descriptive analysis of a hospital-prescribed medication registry.docx
منشور في 2024"…In the sensitivity analysis, the A-level usage rate decreased to one-third and the B-level usage rate increased by 2–3 times. …"
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19533
Supplementary file 2_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx
منشور في 2025"…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV<sub>1</sub>), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …"
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19534
Table 5_Multi-omics reveals effects of diet FNDF/starch level on growth performance and rumen development of Hu sheep.xlsx
منشور في 2025"…The results indicated that average daily gain (ADG) and average daily feed intake (ADFI) of group B, C and D were significantly higher than group A (p < 0.05); the feed conversion ratio (FCR) of group B was significantly higher than other groups (p < 0.05) and the height of rumen papillae in group B and C was significantly higher than in group A (p < 0.05). …"
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19535
DataSheet1_Mechanism of Valeriana officinalis L. extract improving atherosclerosis by regulating PGC-1α/Sirt3/Epac1 pathway.pdf
منشور في 2025"…Furthermore, the drug significantly increased the mRNA and protein expression of PGC-1α and Sirt3 in aortic tissue, while decreasing the mRNA and protein expression of Epac1, Caspase-3, and Caspase-9.…"
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19536
DataSheet1_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.zip
منشور في 2024"…Although the population of F4/80<sup>+</sup>CD11b<sup>+</sup> intrahepatic mononuclear phagocytes remained unchanged, their infiltration and activation (CHIT1<sup>+</sup>MerTK<sup>+</sup>) significantly decreased in OATD-01-treated mice, compared with that observed in vehicle-treated mice.…"
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19537
Sex-specific brain volume changes in ECM.
منشور في 2025"…The total volume of midbrain (F) significantly augments in the female brain during CM. …"
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19538
Image 2_Multi-omics reveals effects of diet FNDF/starch level on growth performance and rumen development of Hu sheep.tif
منشور في 2025"…The results indicated that average daily gain (ADG) and average daily feed intake (ADFI) of group B, C and D were significantly higher than group A (p < 0.05); the feed conversion ratio (FCR) of group B was significantly higher than other groups (p < 0.05) and the height of rumen papillae in group B and C was significantly higher than in group A (p < 0.05). …"
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19539
Supplementary file 1_Bioinformatics analysis combined with experimental validation reveals the novel mechanisms of multi-targets of dapagliflozin attenuating diabetic liver injury....
منشور في 2025"…Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, has shown significant therapeutic benefits in clinical trials for the management of diabetes However, the specific mechanism on the treatment of diabetic liver injury with dapagliflozin is not fully understood. …"
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19540
Image 1_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.png
منشور في 2025"…ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …"