بدائل البحث:
significant challenges » significant challenge (توسيع البحث), significant changes (توسيع البحث)
challenges decrease » challenges case (توسيع البحث)
changes decrease » largest decrease (توسيع البحث), change increases (توسيع البحث)
larger decrease » marked decrease (توسيع البحث)
significant challenges » significant challenge (توسيع البحث), significant changes (توسيع البحث)
challenges decrease » challenges case (توسيع البحث)
changes decrease » largest decrease (توسيع البحث), change increases (توسيع البحث)
larger decrease » marked decrease (توسيع البحث)
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6461
Table 1_Global and regional burdens of opioid use disorder from 1990 to 2021, with future forecasts to 2050: a systematic analysis for the global burden of disease study 2021.docx
منشور في 2025"…Population growth and epidemiological changes contributed significantly to the increase in the burden of OUD.…"
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6462
Table 7_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog...
منشور في 2025"…</p>Results<p>A total of 45 studies met the inclusion criteria, which evaluated microbial changes in H. pylori -infected individuals before and after eradication therapies. …"
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6463
Table 1_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog...
منشور في 2025"…</p>Results<p>A total of 45 studies met the inclusion criteria, which evaluated microbial changes in H. pylori -infected individuals before and after eradication therapies. …"
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6464
Image 2_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif
منشور في 2025"…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1<sup>−/−</sup> mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …"
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6465
Image 6_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif
منشور في 2025"…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1<sup>−/−</sup> mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …"
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6466
Image 5_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif
منشور في 2025"…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1<sup>−/−</sup> mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …"
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6467
Table 4_Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.xlsx
منشور في 2025"…The lactylation levels of Mtatp8, Atp5mg, and Atp5po proteins in the exercise group were significantly decreased, while their protein levels were significantly increased. …"
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6468
Image 3_Entropy as a marker of physiological transition during pediatric cardiopulmonary exercise testing.jpeg
منشور في 2025"…In addition to sex and age group comparisons, we examined SampEn before and after the midpoint of each participant’s CPET to assess how SampEn changes as exercise intensity increases. We corroborated previous findings that SampEn decreases in the later half of CPET for healthy pediatric participants for oxygen uptake (V̇O2), carbon dioxide output (V̇CO2), ventilation (V̇E), and heart rate (HR). …"
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6469
Image 5_Global burden of endometriosis from 1990 to 2021 and projections to 2050: a comprehensive analysis based on the global burden of disease study 2021.tif
منشور في 2025"…Future research should investigate the effects of population aging and lifestyle changes on the burden of EMT.</p>…"
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6470
Image 4_Global burden of endometriosis from 1990 to 2021 and projections to 2050: a comprehensive analysis based on the global burden of disease study 2021.tif
منشور في 2025"…Future research should investigate the effects of population aging and lifestyle changes on the burden of EMT.</p>…"
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6471
Table 2_Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.xlsx
منشور في 2025"…The lactylation levels of Mtatp8, Atp5mg, and Atp5po proteins in the exercise group were significantly decreased, while their protein levels were significantly increased. …"
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6472
Image 4_Entropy as a marker of physiological transition during pediatric cardiopulmonary exercise testing.jpeg
منشور في 2025"…In addition to sex and age group comparisons, we examined SampEn before and after the midpoint of each participant’s CPET to assess how SampEn changes as exercise intensity increases. We corroborated previous findings that SampEn decreases in the later half of CPET for healthy pediatric participants for oxygen uptake (V̇O2), carbon dioxide output (V̇CO2), ventilation (V̇E), and heart rate (HR). …"
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6473
Table8_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.xlsx
منشور في 2024"…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …"
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6474
Data Sheet 1_Identification of the malonylation modification in Staphylococcus aureus and insight into the regulators in biofilm formation.xlsx
منشور في 2025"…</p>Results<p>Quantitative profiling identified 2,833 malonylated sites across 788 proteins, with significant enrichment in biofilm-associated proteins. …"
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6475
Table 5_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog...
منشور في 2025"…</p>Results<p>A total of 45 studies met the inclusion criteria, which evaluated microbial changes in H. pylori -infected individuals before and after eradication therapies. …"
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6476
Data Sheet 1_Involvement of long non-coding RNA (lncRNA) MALAT1 in shear stress regulated adipocyte differentiation.docx
منشور في 2025"…Excessive adipocyte differentiation within the bone marrow microenvironment can lead to decreased bone mass, eventually causing osteoporosis. …"
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6477
Table 1_Analysis of the microstates of prolonged disorders of consciousness.docx
منشور في 2025"…At the same time, the brain connectivity of pDOC patients in the four MS decreased significantly compared to the HG.</p>…"
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6478
Image 4_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.tif
منشور في 2025"…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1<sup>−/−</sup> mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …"
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6479
Data Sheet 3_Identification of the malonylation modification in Staphylococcus aureus and insight into the regulators in biofilm formation.pdf
منشور في 2025"…</p>Results<p>Quantitative profiling identified 2,833 malonylated sites across 788 proteins, with significant enrichment in biofilm-associated proteins. …"
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6480
Table 3_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog...
منشور في 2025"…</p>Results<p>A total of 45 studies met the inclusion criteria, which evaluated microbial changes in H. pylori -infected individuals before and after eradication therapies. …"