يعرض 6,501 - 6,520 نتائج من 8,444 نتيجة بحث عن '(( significant challenges decrease ) OR ( significant ((changes decrease) OR (larger decrease)) ))', وقت الاستعلام: 0.31s تنقيح النتائج
  1. 6501

    Image 3_Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.tif حسب Jiahui Chang (15359305)

    منشور في 2025
    "…The lactylation levels of Mtatp8, Atp5mg, and Atp5po proteins in the exercise group were significantly decreased, while their protein levels were significantly increased. …"
  2. 6502

    Table 1_Multi-omics study on the effect of moderate-intensity exercise on protein lactylation in mouse muscle tissue.xlsx حسب Jiahui Chang (15359305)

    منشور في 2025
    "…The lactylation levels of Mtatp8, Atp5mg, and Atp5po proteins in the exercise group were significantly decreased, while their protein levels were significantly increased. …"
  3. 6503

    Image 3_Global burden of endometriosis from 1990 to 2021 and projections to 2050: a comprehensive analysis based on the global burden of disease study 2021.tif حسب Xiaochuan Yu (2410861)

    منشور في 2025
    "…Future research should investigate the effects of population aging and lifestyle changes on the burden of EMT.</p>…"
  4. 6504

    Table6_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.xlsx حسب Mingming Hou (11341656)

    منشور في 2024
    "…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …"
  5. 6505

    original data.xlsx حسب Peng Shen (20145351)

    منشور في 2024
    "…<b>Research Results</b>: The results showed that the levels of inflammatory factors significantly decreased in the blood purification treatment group after treatment, with a notable reduction in hospitalization and ICU stay duration compared to the conventional treatment group. …"
  6. 6506

    DataSheet1_Interannual temperature rise leads to more uniform phenological matching between invasive Stellera chamaejasme and pollinators across elevations.pdf حسب Chenxin Miao (19834812)

    منشور في 2024
    "…<p>Exploring how environmental changes induce alterations in the phenology matching between plants and pollinators is significant for predicting species’ reproductive output and population dynamics. …"
  7. 6507

    Data Sheet 1_Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.pdf حسب Maria Delgado-Ortet (8840702)

    منشور في 2025
    "…Significant differences were also found between responders and non-responders in the first-order radiomic feature Energy.…"
  8. 6508

    Image2_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.png حسب Mingming Hou (11341656)

    منشور في 2024
    "…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …"
  9. 6509

    Table 2_Carnosine as a protective metabolic mediator in inflammatory lung injury by inhibiting macrophage infiltration and M1-like polarization.xlsx حسب Lianjie Ruan (22660265)

    منشور في 2025
    "…To evaluate its therapeutic potential, we administered exogenous carnosine in both models and assessed its effects on body weight, inflammatory cytokine expression, and histopathological changes.</p>Results<p>Carnosine supplementation significantly improved body weight maintenance, reduced the expression of pro-inflammatory cytokines, and attenuated histological lung damage in both LPS- and papain-induced lung injury models. …"
  10. 6510

    Data Sheet 1_Trifolin inhibits the calcium-driven contraction pathway in vascular smooth muscle.pdf حسب Renfeng Li (126284)

    منشور في 2025
    "…<p>Trifolin, a bioactive component of the Qingda granule, has demonstrated significant antihypertensive potential; however, its precise mechanisms of action remain largely unknown. …"
  11. 6511
  12. 6512

    Table1_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.xlsx حسب Mingming Hou (11341656)

    منشور في 2024
    "…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …"
  13. 6513

    Image 1_High-dose thiamine supplementation ameliorates obesity induced by a high-fat and high-fructose diet in mice by reshaping gut microbiota.tif حسب Yu Xia (8822)

    منشور في 2025
    "…Furthermore, oral administration of high-dose thiamine also regulated HFFD-induced gut microbiota dysbiosis by reshaping its structure and composition of gut microbiota, such as increasing the relative abundance of Actinobacteria and Bifidobacterium pseudolongum, and reducing the relative abundance of Proteobacteria and Ruminococcus gnavus, accompanied by decreased level of gut-derived endotoxin. Finally, significant correlations were found between obesity-related phenotypes and gut microbiota through correlation analysis.…"
  14. 6514

    Data Sheet 1_Sleep is enhanced in aged male mice that overexpress calcium/calmodulin-dependent protein kinase IV.docx حسب Sierra P. Feeney (21466928)

    منشور في 2025
    "…<p>The dysregulation of sleep–wake patterns that occurs during aging is well documented and coincides with changes in intracellular signaling pathways that regulate sleep, such as the calcium/calmodulin-dependent protein kinase (CaMKII)/cyclic-AMP response element-binding protein (CREB) pathway. …"
  15. 6515

    Table3_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.xlsx حسب Mingming Hou (11341656)

    منشور في 2024
    "…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …"
  16. 6516

    Image 2_Global burden of endometriosis from 1990 to 2021 and projections to 2050: a comprehensive analysis based on the global burden of disease study 2021.tif حسب Xiaochuan Yu (2410861)

    منشور في 2025
    "…Future research should investigate the effects of population aging and lifestyle changes on the burden of EMT.</p>…"
  17. 6517

    Table 2_Bmi1 deficiency exacerbates hyperoxia-induced acute lung injury in mice.docx حسب Helena Hernández-Cuervo (9956465)

    منشور في 2025
    "…</p>Results<p>Mice lacking Bmi1 versus WT exposed to hyperoxia exhibited hallmarks of human acute lung injury (ALI) such as increased lung permeability, alveolar edema, hemorrhage, interstitial thickening, and infiltration of immune cells; and alterations in lung mechanics, including increased elastance and decreased lung compliance.</p>Discussion<p>Bmi1<sup>−/−</sup> mice exhibit increased mitochondrial damage, increased oxidative stress, and significant changes in protein markers related to mitophagy compared to WT mice. …"
  18. 6518

    Table 1_In vivo profiling of the PE/PPE proteins of Mycobacterium tuberculosis reveals diverse contributions to virulence.xlsx حسب Benjamin Koleske (11581641)

    منشور في 2025
    "…We found consistent, time-dependent changes in mutant abundance across our animal replicates and identified decreases in several key mutant strains known to promote bacterial growth or virulence. …"
  19. 6519

    Data Sheet 1_Mechanism of salidroside promoting testosterone secretion induced by H2O2 in TM3 Leydig cells based on metabolomics and network pharmacology.zip حسب Zixu Wang (6297470)

    منشور في 2025
    "…The study investigated the oxidative damage in TM3 cells induced by H<sub>2</sub>O<sub>2</sub> and demonstrated that salidroside significantly decreased the levels of ROS and MDA, while increasing the levels of testosterone, SOD, GSH. …"
  20. 6520

    Supplementary file 1_Monitoring the dual-season hydrological dynamics of the Pong reservoir in Himachal Pradesh, India.docx حسب Rajesh Sarda (13162317)

    منشور في 2025
    "…The 30 years were divided into three phases to assess changes in hydrological consistency and relative water depth over time. …"