يعرض 11,361 - 11,380 نتائج من 11,452 نتيجة بحث عن '(( significant challenges decrease ) OR ( significant ((level decrease) OR (mean decrease)) ))', وقت الاستعلام: 0.57s تنقيح النتائج
  1. 11361

    DataSheet1_α-Mangostin Alleviated Inflammation in Rats With Adjuvant-Induced Arthritis by Disrupting Adipocytes-Mediated Metabolism-Immune Feedback.PDF حسب Ying-Hao Hu (11087037)

    منشور في 2025
    "…Generally, MAN restored the impaired fat anabolism in AIA rats, indicated by increased fat reservoir, leptin and adiponectin secretion, and PPAR-γ and SCD-1 expression. Meanwhile, it decreased circulating IL-1β and IL-6 levels, restored serological lipid profile changes, and relieved oxidative stresses, demonstrating potent therapeutic effects on AIA. …"
  2. 11362

    Data Sheet 1_A novel short-course, low-intensity blood-flow-restricted exercise (BFRE) regimen to study satellite cell function in critical illness survivors with sustained muscle... حسب Sunita Mathur (759075)

    منشور في 2025
    "…In controls, satellite cell content and MuRF1 transcript expression were significantly higher (1.53 ± 0.30- and 1.34 ± 0.31-fold difference, respectively) and myostatin transcript expression was significantly lower (0.58 ± 0.31-fold difference) in BFRE-trained versus untrained VL. …"
  3. 11363

    Table1_Vermicompost application improves leaf physiological activity, 2-acetyl-1-pyrroline, and grain yield of fragrant rice through efficient nitrogen assimilation under Cd stress... حسب Anas Iqbal (9471071)

    منشور في 2024
    "…In addition, VC application significantly (p < 0.05) decreased the Cd uptake and accumulation in rice plants. …"
  4. 11364

    Matched data. حسب Feng Zhang (6548)

    منشور في 2025
    "…The observation group showed significantly lower levels of white blood cell count (WBC), neutrophil count (NEUT), lymphocyte count (LYM), red blood cell count (RBC), hemoglobin (HGB), and albumin (ALB) compared to the control group (P < 0.05). …"
  5. 11365

    Supplementary file 1_Bone marrow adipose tissue expansion and bone loss in experimental chronic kidney disease is independent of altered bone marrow stromal cell lineage determinat... حسب Worachet Promruk (22286701)

    منشور في 2025
    "…Serum biochemistries were quantified using a biochemistry analyzer and plasma hormone levels by ELISA. Bone phenotypes were evaluated by µCT. …"
  6. 11366

    Table 3_Integrated analysis of miRNAs-mRNAs in skeletal muscle development revealed that novel-miR-766 affects myoblast differentiation and myofiber-type formation in sheep.xlsx حسب Zhenzhen Gu (21488168)

    منشور في 2025
    "…In vitro assays revealed that myoblast differentiation and myotube formation were significantly inhibited by MYH3 knockdown via siMYH3 and that novel-miR-766 targets and decreases the expression of MYH3. …"
  7. 11367

    Nomogram model. حسب Feng Zhang (6548)

    منشور في 2025
    "…The observation group showed significantly lower levels of white blood cell count (WBC), neutrophil count (NEUT), lymphocyte count (LYM), red blood cell count (RBC), hemoglobin (HGB), and albumin (ALB) compared to the control group (P < 0.05). …"
  8. 11368

    Table 5_Integrated analysis of miRNAs-mRNAs in skeletal muscle development revealed that novel-miR-766 affects myoblast differentiation and myofiber-type formation in sheep.xlsx حسب Zhenzhen Gu (21488168)

    منشور في 2025
    "…In vitro assays revealed that myoblast differentiation and myotube formation were significantly inhibited by MYH3 knockdown via siMYH3 and that novel-miR-766 targets and decreases the expression of MYH3. …"
  9. 11369

    Data Sheet 1_Molecular mechanisms of deer antler in promoting osteogenic differentiation of human mesenchymal stem cells via JUN modulation.zip حسب Chengcheng Yu (6663170)

    منشور في 2025
    "…Machine learning approaches highlighted 7 critical genes, with JUN emerging as the core gene. JUN levels were significantly decreased during osteogenic differentiation, showing high diagnostic accuracy (AUCs: 0.977-1.000). …"
  10. 11370

    Table 6_Integrated analysis of miRNAs-mRNAs in skeletal muscle development revealed that novel-miR-766 affects myoblast differentiation and myofiber-type formation in sheep.xlsx حسب Zhenzhen Gu (21488168)

    منشور في 2025
    "…In vitro assays revealed that myoblast differentiation and myotube formation were significantly inhibited by MYH3 knockdown via siMYH3 and that novel-miR-766 targets and decreases the expression of MYH3. …"
  11. 11371

    Supplementary Material for: DOT1L regulates cellular senescence during the progression from acute kidney injury to chronic kidney disease via the micro-222-5p/WNT9B signaling pathw... حسب figshare admin karger (2628495)

    منشور في 2025
    "…In the doxorubicin -induced HK-2 cell model, DOT1L inhibition markedly decreased cellular senescence and lowered mRNA and protein levels of senescence markers, while alleviating cell cycle arrest. …"
  12. 11372

    Autophagy induced by mechanical stress sensitizes cells to ferroptosis by NCOA4-FTH1 axis حسب Chenyu Luo (12443535)

    منشور في 2025
    "…In this study, we reveal that heightened mechanical tension sensitizes cells to ferroptosis, whereas decreased mechanics confers resistance. Mechanistically, reduced mechanical tension reduces intracellular free iron levels by enhancing FTH1 protein expression. …"
  13. 11373

    Table 1_Molecular mechanisms of deer antler in promoting osteogenic differentiation of human mesenchymal stem cells via JUN modulation.docx حسب Chengcheng Yu (6663170)

    منشور في 2025
    "…Machine learning approaches highlighted 7 critical genes, with JUN emerging as the core gene. JUN levels were significantly decreased during osteogenic differentiation, showing high diagnostic accuracy (AUCs: 0.977-1.000). …"
  14. 11374

    Data Sheet 2_Soy-based purified ingredient diet affects mouse gut permeability and the microbiome in fragile X mice.pdf حسب Cara J. Westmark (9302270)

    منشور في 2025
    "…Gut permeability was quantified by FITC-dextran levels in blood plasma. The cecal microbiome was identified by 16S rRNA sequencing. …"
  15. 11375

    Flowchart of Study Design and Analysis. حسب Feng Zhang (6548)

    منشور في 2025
    "…The observation group showed significantly lower levels of white blood cell count (WBC), neutrophil count (NEUT), lymphocyte count (LYM), red blood cell count (RBC), hemoglobin (HGB), and albumin (ALB) compared to the control group (P < 0.05). …"
  16. 11376

    Table 7_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx حسب Zhijian Zha (19451405)

    منشور في 2025
    "…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …"
  17. 11377

    Table 2_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.xlsx حسب Jing Wang (6206297)

    منشور في 2025
    "…Furthermore, ACTR6 overexpression showed a strong connection with immune cell infiltration levels and clinical and pathological factors linked to a poor prognosis. …"
  18. 11378

    Table 1_SRC is a potential target of Arctigenin in treating triple-negative breast cancer: based on machine learning algorithms, molecular modeling and in Vitro test.xlsx حسب Yuezhou Huang (9998177)

    منشور في 2025
    "…Western blotting indicated that AG significantly reduced the levels of Bcl-2, caspase-3, and caspase-9, as well as decreased SRC, p-PI3K-p85, p-AKT1, p-MEK1/2, and p-ERK1/2 expression in TNBC cells in a concentration dependent manner.…"
  19. 11379

    Multivariate Binary Logistic Regression Analysis. حسب Feng Zhang (6548)

    منشور في 2025
    "…The observation group showed significantly lower levels of white blood cell count (WBC), neutrophil count (NEUT), lymphocyte count (LYM), red blood cell count (RBC), hemoglobin (HGB), and albumin (ALB) compared to the control group (P < 0.05). …"
  20. 11380

    Table 1_Global, regional, and national esophageal cancer deaths and DALYs attributable to diet low in vegetables and fruits, 1990–2019: analysis for the global burden of disease st... حسب Bing Cui (179696)

    منشور في 2025
    "…The disease burden attributable to insufficient fruit intake (51,210 deaths, 12,497,75 DALYs) was significantly higher than that from inadequate vegetable intake (17,176 deaths, 4,203,09 DALYs). …"