Showing 2,641 - 2,660 results of 2,801 for search '(( significant challenges decrease ) OR ( significant ((side decrease) OR (step decrease)) ))', query time: 0.60s Refine Results
  1. 2641

    Video 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

    Published 2025
    “…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …”
  2. 2642

    Image1_Oleic acid attenuates asthma pathogenesis via Th1/Th2 immune cell modulation, TLR3/4-NF-κB-related inflammation suppression, and intrinsic apoptotic pathway induction.tif by Soon-Young Lee (4721136)

    Published 2024
    “…The incidence is expected to increase as the average life expectancy increases, highlighting asthma as a significant health challenge in an aging society. The etiology of asthma is linked to an imbalance of Th1 and Th2 cells, respiratory inflammation, and pulmonary cell proliferation. …”
  3. 2643

    Video 5_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

    Published 2025
    “…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …”
  4. 2644

    Data Sheet 1_Association of oxidative balance score with all-cause and cardiovascular mortality among patients with cardio-renal-metabolic disease.docx by Yucui Lin (21598376)

    Published 2025
    “…Moreover, Higher OBS quartiles were linked to a decreased risk of cardiovascular mortality, while no significant reduction was observed in the lower quartiles [model 3: Q2, Q3, Q4: aHR (95CI%) = 0.96(0.77–1.19), 0.78 (0.63–0.97), 0.70 (0.53–0.93), respectively; P for trend = 0.003]. …”
  5. 2645

    Video 1_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

    Published 2025
    “…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …”
  6. 2646

    Image 2_Analysis and contrast of psoriasis disease burden trends in China and globally from 1990 to 2021.tif by Keyi Yu (8958845)

    Published 2025
    “…</p>Conclusion<p>Psoriasis poses a substantial public health challenge in China due to the country’s large and increasingly aging populace. …”
  7. 2647

    Data Sheet 1_The multivalent passive immune-protective vaccines of egg yolk immunoglobulin Y derived from live or inactivated Pseudomonas anguilliseptica against aquaculture pathog... by Pan Cui (5726669)

    Published 2025
    “…Furthermore, the structures of the kidney, spleen, and intestinal tissues were intact, and the expression of p53 and γH2A.X decreased in the kidney.</p>Conclusion<p>L-PA-IgY and I-PA-IgY can resist multiple bacterial infections and have immunoprotective effects with no significant differences. …”
  8. 2648

    Video 6_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

    Published 2025
    “…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …”
  9. 2649

    Data Sheet 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx by Lina Ouologuem (22489549)

    Published 2025
    “…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …”
  10. 2650

    Video 4_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

    Published 2025
    “…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …”
  11. 2651

    Data Sheet 1_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx by Lina Ouologuem (22489549)

    Published 2025
    “…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …”
  12. 2652

    Data Sheet 1_IDO1-AhR axis increases T regulatory cells in Plasmodium vivax malaria infection.pdf by Rafaella Oliveira dos Santos (21710366)

    Published 2025
    “…Introduction<p>Malaria remains a significant public health challenge in Brazil, where Plasmodium vivax (P. vivax) is the predominant species. …”
  13. 2653

    Video 3_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

    Published 2025
    “…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …”
  14. 2654

    Video 7_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 by Lina Ouologuem (22489549)

    Published 2025
    “…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …”
  15. 2655

    DataSheet1_Effects of mesenchymal stromal cells and human recombinant Nerve Growth Factor delivered by bioengineered human corneal lenticule on an innovative model of diabetic reti... by Letizia Pelusi (9606879)

    Published 2024
    “…In the last years, mesenchymal stromal cells (MSCs) and neurotrophins like Nerve Growth Factor (NGF), have garnered significant attention as innovative therapeutic approaches targeting DR-associated neurodegeneration. …”
  16. 2656

    Image 1_Regulation effect of seed priming on sowing rate of direct seeding of rice under salt stress.pdf by Yicheng Zhang (790286)

    Published 2025
    “…However, the global intensification of soil salinization presents a significant challenge to food security. Increasing sowing rates is a common practice to enhance germination under salt stress, although it leads to higher seed costs. …”
  17. 2657

    Table 1_CD9 regulates proliferation, invasion, migration and radioresistance of esophageal squamous cell carcinoma by activating AKT/GSK3β signaling pathway.docx by Liubing Hou (10888140)

    Published 2025
    “…Background<p>Radioresistance poses a major therapeutic challenge in ESCC, significantly impacting patient prognosis. …”
  18. 2658

    Table 1_Regulation effect of seed priming on sowing rate of direct seeding of rice under salt stress.pdf by Yicheng Zhang (790286)

    Published 2025
    “…However, the global intensification of soil salinization presents a significant challenge to food security. Increasing sowing rates is a common practice to enhance germination under salt stress, although it leads to higher seed costs. …”
  19. 2659

    Data Sheet 1_The efficacy and safety of panax quinquefolius saponin for heart failure: a systematic review and meta-analysis.pdf by Jing Wang (6206297)

    Published 2025
    “…Background<p>Heart failure (HF) is a global health concern, affecting millions of individuals worldwide and leading to significant morbidity and mortality. Despite advances in conventional therapeutic strategies, the prognosis for HF patients remains challenging, and there is a constant search for novel therapeutic options. …”
  20. 2660

    Heart looping variations in <i>Notch3</i> and <i>Nodal</i> compound mutants. by Tobias Holm Bønnelykke (20968460)

    Published 2025
    “…(<b>F</b>) Brightfield images of wild type (f1), control <i>Notch3</i> heterozygote (f2) compared to homozygote <i>Nodal</i> mutants with decreased <i>Notch3</i> (f3) at E9.5, in a ventral view. …”