يعرض 2,221 - 2,240 نتائج من 2,385 نتيجة بحث عن '(( significant challenges decrease ) OR ( significant ((step decrease) OR (nn decrease)) ))', وقت الاستعلام: 0.55s تنقيح النتائج
  1. 2221

    Data Sheet 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.xlsx حسب Yu Chen (29959)

    منشور في 2025
    "…Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…"
  2. 2222

    Table 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.docx حسب Yu Chen (29959)

    منشور في 2025
    "…Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…"
  3. 2223

    Image 2_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.pdf حسب Xu Zheng (296676)

    منشور في 2025
    "…</p>Conclusion<p>The disease burden of hip dislocation remains a significant public health challenge. Data-driven analysis is pivotal for guiding clinical practice, shaping public health policies, and ensuring optimal allocation of healthcare resources. …"
  4. 2224

    Preeclamptic plasma disrupts endothelial function and promotes inflammation in endothelial cells: beneficial effects of glibenclamide and MCC950 in this scenario حسب Karoliny Nune Santos (21752603)

    منشور في 2025
    "…<p>Preeclampsia (PE) is characterized by systemic endothelial dysfunction and remains a significant clinical challenge. Activation of NLRP3 inflammasome, reactive oxygen species (ROS) production, and pyroptosis and autophagy are important mechanisms in this condition. …"
  5. 2225

    Image 1_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.tif حسب Xu Zheng (296676)

    منشور في 2025
    "…</p>Conclusion<p>The disease burden of hip dislocation remains a significant public health challenge. Data-driven analysis is pivotal for guiding clinical practice, shaping public health policies, and ensuring optimal allocation of healthcare resources. …"
  6. 2226

    Table 2_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.docx حسب Xu Zheng (296676)

    منشور في 2025
    "…</p>Conclusion<p>The disease burden of hip dislocation remains a significant public health challenge. Data-driven analysis is pivotal for guiding clinical practice, shaping public health policies, and ensuring optimal allocation of healthcare resources. …"
  7. 2227

    Table 1_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.docx حسب Xu Zheng (296676)

    منشور في 2025
    "…</p>Conclusion<p>The disease burden of hip dislocation remains a significant public health challenge. Data-driven analysis is pivotal for guiding clinical practice, shaping public health policies, and ensuring optimal allocation of healthcare resources. …"
  8. 2228

    AjMLKL is involved in 10<sup>8</sup> CFU/mL AJ01 induced lytic coelomocyte death independent on its phosphorylation. حسب Kaiyu Chen (11691918)

    منشور في 2025
    "…Treatment of sea cucumber coelomocytes with 100 μM GW806724X for 3 h and then challenged by 10<sup>8</sup> CFU/mL AJ01. Coelomocyte viability was significantly increased (L), and coelomocytes plasma membrane disruption (M) and the percentage of Annexin V+/PI+ coelomocytes significantly decreased (N). …"
  9. 2229

    Image 1_Analysis and contrast of psoriasis disease burden trends in China and globally from 1990 to 2021.tiff حسب Keyi Yu (8958845)

    منشور في 2025
    "…</p>Conclusion<p>Psoriasis poses a substantial public health challenge in China due to the country’s large and increasingly aging populace. …"
  10. 2230

    Video 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 حسب Lina Ouologuem (22489549)

    منشور في 2025
    "…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …"
  11. 2231

    Image1_Oleic acid attenuates asthma pathogenesis via Th1/Th2 immune cell modulation, TLR3/4-NF-κB-related inflammation suppression, and intrinsic apoptotic pathway induction.tif حسب Soon-Young Lee (4721136)

    منشور في 2024
    "…The incidence is expected to increase as the average life expectancy increases, highlighting asthma as a significant health challenge in an aging society. The etiology of asthma is linked to an imbalance of Th1 and Th2 cells, respiratory inflammation, and pulmonary cell proliferation. …"
  12. 2232

    Video 5_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 حسب Lina Ouologuem (22489549)

    منشور في 2025
    "…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …"
  13. 2233

    Data Sheet 1_Association of oxidative balance score with all-cause and cardiovascular mortality among patients with cardio-renal-metabolic disease.docx حسب Yucui Lin (21598376)

    منشور في 2025
    "…Moreover, Higher OBS quartiles were linked to a decreased risk of cardiovascular mortality, while no significant reduction was observed in the lower quartiles [model 3: Q2, Q3, Q4: aHR (95CI%) = 0.96(0.77–1.19), 0.78 (0.63–0.97), 0.70 (0.53–0.93), respectively; P for trend = 0.003]. …"
  14. 2234

    Video 1_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 حسب Lina Ouologuem (22489549)

    منشور في 2025
    "…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …"
  15. 2235

    Image 2_Analysis and contrast of psoriasis disease burden trends in China and globally from 1990 to 2021.tif حسب Keyi Yu (8958845)

    منشور في 2025
    "…</p>Conclusion<p>Psoriasis poses a substantial public health challenge in China due to the country’s large and increasingly aging populace. …"
  16. 2236

    Data Sheet 1_The multivalent passive immune-protective vaccines of egg yolk immunoglobulin Y derived from live or inactivated Pseudomonas anguilliseptica against aquaculture pathog... حسب Pan Cui (5726669)

    منشور في 2025
    "…Furthermore, the structures of the kidney, spleen, and intestinal tissues were intact, and the expression of p53 and γH2A.X decreased in the kidney.</p>Conclusion<p>L-PA-IgY and I-PA-IgY can resist multiple bacterial infections and have immunoprotective effects with no significant differences. …"
  17. 2237

    Video 6_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 حسب Lina Ouologuem (22489549)

    منشور في 2025
    "…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …"
  18. 2238

    Data Sheet 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx حسب Lina Ouologuem (22489549)

    منشور في 2025
    "…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …"
  19. 2239

    Video 4_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4 حسب Lina Ouologuem (22489549)

    منشور في 2025
    "…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …"
  20. 2240

    Data Sheet 1_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.docx حسب Lina Ouologuem (22489549)

    منشور في 2025
    "…Introduction<p>Hepatocellular carcinoma (HCC) remains a major global health challenge, characterised by limited therapeutic options and high mortality rates. …"