Supplementary file 1_Global burden and trends of adverse effects of medical treatment, 1990–2021: an analysis from the global burden of disease study 2021.docx by Keqing Zhang (326894)

“…By 2036, it is forecast that ASIR will decrease to 72.33 (19.40–125.27) per 100,000 persons-year, and ASDR will decrease to 40.98 (21.52–60.43) per 100,000 persons-year.…”

Data_Sheet_1_Dietary patterns, genetic predisposition, and risk of cholelithiasis: a large-scale prospective cohort study.pdf by Kecheng Jin (19748674)

“…</p>Conclusion<p>Higher adherence to aMED and HEI-2015 might significantly decrease the risk of cholelithiasis, irrespective of genetic risk. …”

Table 3_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 4_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 6_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 2_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Table 5_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

The relationship between serum uric acid and gastrointestinal bleeding in peritoneal dialysis patients: a propensity score analysis by Guowen Zhao (19775328)

“…In subgroups, the interaction between higher levels of uric acid and utilizing proton pump inhibitors was significant (P for interaction = 0.034). Further research found that taking proton pump inhibitors could decrease the risk of gastrointestinal bleeding in peritoneal dialysis patients accompanied high levels of uric acid.…”

Image 1_Association between cardiometabolic Index and obstructive sleep apnea and the mediating role of smoking: a cross-sectional study.tif by Yifan Zhou (1973332)

“…Additionally, the findings from the threshold effects analysis indicate that maintaining CMI within an appropriate range can significantly decrease the likelihood of developing OSA.…”

Table 1_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Supplementary file 1_Loss of SynDIG4/PRRT1 alters distribution of AMPA receptors in Rab4- and Rab11-positive endosomes and impairs basal AMPA receptor recycling.pdf by Chun-Wei He (3909592)

“…We did not observe any change in baseline endocytosis; however, we did observe a significant decrease in recycling of GluA1-containing AMPARs in cultured hippocampal neurons from mice lacking SynDIG4. …”

Table 1_Association between cardiometabolic Index and obstructive sleep apnea and the mediating role of smoking: a cross-sectional study.docx by Yifan Zhou (1973332)

“…Additionally, the findings from the threshold effects analysis indicate that maintaining CMI within an appropriate range can significantly decrease the likelihood of developing OSA.…”

Non-consumptive effects of <i>Cyrtorhinus lividipennis</i> (Hemiptera: Miridae) on development, wing dimorphism, and reproduction in <i>Sogatella furcifera</i> (Hemiptera: Delphaci... by Meng Yang (162251)

“…Exposure to predation risk caused <i>S. furcifera</i> nymphs to delay their development, increased the proportion of long-winged adult females, and significantly reduced the number of eggs laid. Further analysis of physiological indices showed that key genes involved in wing-morph switching and ecdysone (20E) synthesis were downregulated after exposure to predation risk, accompanied by a significant decrease in the 20E titre in the 4th instar, which may represent a potential regulatory mechanism of planthoppers in response to predator stress. …”

Supplementary Material for: Alcohol use and types and ischemic stroke: a systematic review and meta-analysis by figshare admin karger (2628495)

“…Moderate alcohol use was associated with significant decrease in ischemic stroke risk (RR=0.87; 95% CI 0.83-0.92) while heavy alcohol use was associated with significant increase in ischemic stroke risk (RR=1.31; 95% CI 1.19-1.44). …”

Table 1_Potential shared gene signatures and molecular mechanisms between recurrent pregnancy loss and ovarian cancer.docx by Yan Wang (15435)

“…</p>Methods<p>The 71 differentially expressed genes associated with RPL and 1427 genes associated with OV survival were analyzed, among which 7 common genes were both important in the pathogenesis of RPL and OV. Then stepAIC analysis was performed to simplify the model and decrease the number of genes, which yielded a final set of 5 prognostic genes with coefficients to construct a prognostic risk scoring system. …”

Supplementary Material for: Effects of wearing hearing aids on gait and cognition: A pilot study by figshare admin karger (2628495)

“…Intention-to-treat analyses showed improvements in step time at both usual and maximum paces associated with HA use. …”

Data Sheet 1_Rice glycosyltransferase OsDUGT1 is involved in heat stress tolerance by glycosylating flavonoids and regulating flavonoid metabolism.doc by Guang-rui Dong (11871026)

“…Correspondingly, the loss of OsDUGT1 function caused a significant decrease in endogenous flavonoid accumulation in rice, which was demonstrated by our metabolomics analysis. …”

Data Sheet 1_A taste of one’s own medicine: Bacillus velezensis isolated from adult housefly intestines demonstrates effective fly control.pdf by Ying Li (38224)

“…Additionally, we observed a significant decrease in immune response in housefly larvae, with a reduction in phenoloxidase activity and melanization ability in treated larvae compared to controls.…”

Table 1_Analysis of the microbiota of pregnant women in relation to weight gain during pregnancy – a pilot study.docx by Katarzyna Kosinska-Kaczynska (6794522)

“…However, in both sites none difference was found to be statistically significant after p-value correction.</p>Conclusions<p>Despite small sample size, we demonstrated slight trends in microbiota composition between groups. …”

Table1_Exposure to air pollution and the risk of type II diabetes mellitus: a time-series study.docx by Zhuomin Hou (20372874)

“…</p>Methods<p>We collected data on patients with T2DM from three healthcare institutions in Xinxiang from 2016–2021. …”