يعرض 7,361 - 7,380 نتائج من 7,576 نتيجة بحث عن '(( significant challenges decrease ) OR ( significant ((we decrease) OR (step decrease)) ))', وقت الاستعلام: 0.61s تنقيح النتائج
  1. 7361

    Data Sheet 1_Changes in sST2 and NT-proBNP levels predict early cardiac arrhythmia in breast cancer patients treated with anthracycline-containing chemotherapies.pdf حسب Cuncun Chen (11842427)

    منشور في 2024
    "…</p>Results<p>sST2 levels increased significantly from baseline to C1 (P < 0.01). NT-proBNP levels decreased from baseline to C1 and C5 (P < 0.01). …"
  2. 7362

    Table 7_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx حسب Zhijian Zha (19451405)

    منشور في 2025
    "…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …"
  3. 7363

    Table 1_Efficacy and safety of sofosbuvir plus daclatasvir in hemodialysis patients with genotype 1b or 2a hepatitis C virus infection: a single-arm, prospective real-world study.x... حسب Kaili Wang (2246485)

    منشور في 2025
    "…One participant was lost to follow-up. APRI scores significantly decreased from baseline (0.56) to week 24 (0.20, p < 0.001). …"
  4. 7364

    Image 4_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff حسب Priscila Silva (556743)

    منشور في 2025
    "…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …"
  5. 7365

    Table 1_Global, regional, and national esophageal cancer deaths and DALYs attributable to diet low in vegetables and fruits, 1990–2019: analysis for the global burden of disease st... حسب Bing Cui (179696)

    منشور في 2025
    "…</p>Methods<p>Using the Global Burden of Disease Study 2019 (GBD 2019) database, we conducted descriptive analyses stratified by age, sex, Socio-demographic Index (SDI), and regional levels. …"
  6. 7366

    Table 2_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx حسب Zhijian Zha (19451405)

    منشور في 2025
    "…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …"
  7. 7367

    Supplementary file 1_Quantitative microbial taxonomy across particle size, depth, and oxygen concentration.zip حسب Paulina Huanca-Valenzuela (21414911)

    منشور في 2025
    "…The microbial community varied statistically significantly as a function of particle size and depth. …"
  8. 7368

    Table 3_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx حسب Zhijian Zha (19451405)

    منشور في 2025
    "…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …"
  9. 7369

    Table 1_Global, regional, and national burden of myocarditis and its attributable risk factors in 204 countries and territories from 1990 to 2021: updated systematic analysis.docx حسب Jiajia Ren (11151738)

    منشور في 2025
    "…Concurrently, the age-standardized prevalence rate (ASPR) per 100,000 people also saw a slight increase (no statistical significance) from 6.35 (5.37 to 7.36) to 6.41 (5.48 to 7.44). …"
  10. 7370

    Image 2_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff حسب Priscila Silva (556743)

    منشور في 2025
    "…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …"
  11. 7371

    P23 <i>Rik</i><sup><i>null</i></sup> vs. WT DEGs. حسب Erdyni N. Tsitsikov (20384719)

    منشور في 2024
    "…<div><p>Here, we describe a spontaneous mouse mutant with a deletion in a predicted gene <i>2310061I04Rik</i> (<i>Rik</i>) of unknown function located on chromosome 17. …"
  12. 7372

    Image 2_Plant-based diets and total and cause-specific mortality: a meta-analysis of prospective studies.tif حسب Qiwang Mo (9091292)

    منشور في 2025
    "…Participants in the highest quintile of both the PDI and hPDI had a significantly decreased risk of all-cause mortality (pooled HR<sub>PDI</sub> = 0.85; 95% CI: 0.80–0.90; pooled HR<sub>hPDI</sub> = 0.86; 95% CI: 0.81–0.92) compared to participants in the lowest quintile. …"
  13. 7373

    Table 1_Oral bacterial community dynamics during induction of gingival inflammation.xlsx حسب Bart J. F. Keijser (16884185)

    منشور في 2025
    "…</p>Results<p>The study revealed pronounced microbial changes, particularly in supragingival plaque, where Leptotrichia and Prevotella increased while Streptococcus decreased. Alpha diversity significantly increased in supragingival plaque, tongue, and saliva during gingivitis induction, highlighting shifts in microbial complexity. …"
  14. 7374

    Table 1_Effects of folic acid with vitamin B12/vitamin B6 intervention on serum homocysteine metabolism and complications in patients with type 2 diabetes: a systematic review and... حسب Yaqi Yin (7280069)

    منشور في 2025
    "…Supplementation with folic acid plus vitamin B12 (SMD = −2.77, 95% CI [−3.23, −2.30], P < 0.0001) significantly reduced serum homocysteine levels and decreased the incidence of total complications (RR = 0.30, 95% CI [0.24, 0.38], P < 0.0001). …"
  15. 7375

    Image 3_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif حسب Rong Su (2210740)

    منشور في 2025
    "…However, the risk associated with RNA methylation-related miRNAs (RMRMs) in the HCC immune microenvironment remains largely unknown. Here, we predicted the correlation between RMRM risk and immune cell infiltration in HCC using machine learning. …"
  16. 7376

    DataSheet1_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf حسب Jianan Zhang (786459)

    منشور في 2025
    "…Up-regulation of DYNLT3 expression significantly inhibited tumor growth in a nude mouse model, while downregulation of DYNLT3 showed the opposite results. …"
  17. 7377

    Image 2_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif حسب Rong Su (2210740)

    منشور في 2025
    "…However, the risk associated with RNA methylation-related miRNAs (RMRMs) in the HCC immune microenvironment remains largely unknown. Here, we predicted the correlation between RMRM risk and immune cell infiltration in HCC using machine learning. …"
  18. 7378

    Image 1_Plant-based diets and total and cause-specific mortality: a meta-analysis of prospective studies.tif حسب Qiwang Mo (9091292)

    منشور في 2025
    "…Participants in the highest quintile of both the PDI and hPDI had a significantly decreased risk of all-cause mortality (pooled HR<sub>PDI</sub> = 0.85; 95% CI: 0.80–0.90; pooled HR<sub>hPDI</sub> = 0.86; 95% CI: 0.81–0.92) compared to participants in the lowest quintile. …"
  19. 7379

    Image 1_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tif حسب Priscila Silva (556743)

    منشور في 2025
    "…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …"
  20. 7380

    Table 1_Ayahuasca partially preserves striatal integrity in juvenile non-human primates exposed to chronic stress: evidence from stereological evaluation.docx حسب Wigínio Gabriel de Lira-Bandeira (20749421)

    منشور في 2025
    "…Depression, a complex psychiatric disorder, affects millions of people around the world and leads to an increased risk of suicide, decreased quality of life, and functional impairment. …"