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challenges decrease » challenges case (Expand Search)
significant challenges » significant challenge (Expand Search), significant changes (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
challenges decrease » challenges case (Expand Search)
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18301
Image 1_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png
Published 2025“…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …”
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18302
Image 5_Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia.png
Published 2025“…Functionally, iron overload decreased the phagocytic function of LAMs against leukemia cells and inhibited LAM-induced T cell activation by acquiring a tolerogenic phenotype with aberrant immune checkpoints. …”
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18303
Data Sheet 1_Therapeutic potential of Glycyrrhiza polysaccharides in pseudorabies virus infection: immune modulation, antioxidant activity, and gut microbiota restoration.pdf
Published 2025“…</p>Results<p>GP administration significantly alleviated PRV-induced symptoms, reduced mortality and disease activity index, and improved food intake. …”
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18304
<b>Combination of isobavachalcone and amphotericin B has antifungal effect against </b><b>Cryptococcus neoformans</b><b>and protects host tissue damage by inhibiting ferroptosis</b...
Published 2025“…The results demonstrated that IBC (4 μg/mL) significantly reduced the minimum inhibitory concentration (MIC) of AmB from 1 μg/mL to 0.25 μg/mL, indicating a fourfold increase in potency. …”
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18305
Table 1_Metabolic changes after growth hormone treatment in children with growth hormone deficiency and small for gestational age: LG observational study.docx
Published 2025“…ALT levels significantly decreased in all follow-up years in the GHD group. …”
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18306
Data Sheet 1_Succinic acid improves crop chemical components by regulating soil chemical properties, microbes and metabolites.docx
Published 2025“…The relative abundance of Proteobacteria in the bacterial community was significantly decreased, while that of Chloroflexi was significantly increased. …”
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18307
<b>Supplementary Fig. 1</b>
Published 2025“…Erlotinib treatment significantly decreased phospho-ERK levels at both concentrations (figure 1, left). …”
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18308
<b>Supplementary Figure 1</b>
Published 2024“…Erlotinib treatment significantly decreased phospho-ERK levels at both concentrations (figure 1, left). …”
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18309
DataSheet1_Dectin-1 participates in the immune-inflammatory response to mouse Aspergillus fumigatus keratitis by modulating macrophage polarization.doc
Published 2024“…The number of macrophages in the corneal stroma of mice in the curdlan pretreatment group increased significantly compared with the PBS group, while in the laminaran pretreatment group this number decreased significantly. 5. …”
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18310
Data_Sheet_1_RETRACTED: The Variation of Nasal Microbiota Caused by Low Levels of Gaseous Ammonia Exposure in Growing Pigs.pdf
Published 2025“…Four microbial genera (Pseudomonas, Lactobacillus, Prevotella, and Bacteroides) were significantly decreased at 25 ppm, while only two genera (Moraxella and Streptococcus) were increased at 25 ppm. …”
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18311
Validation of FGF9 expression in external database and NRK-52E cells.
Published 2025“…<p>(A) The expression of FGF9 in the GSE30122 database was significantly decreased. (B) The expression of FGF9 in the GSE96804 database was significantly decreased. …”
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18312
Table 1_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.docx
Published 2025“…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”
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18313
Image 3_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.jpeg
Published 2025“…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”
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18314
Image 1_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.jpeg
Published 2025“…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”
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18315
Image 2_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.jpeg
Published 2025“…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”
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18316
Image 4_VdAHA1 positively regulate pathogenicity in Verticillium dahliae.jpeg
Published 2025“…The VdAHA1 knockout mutants showed increased drug sensitivity to ergosterol synthesis pathway, significantly inhibiting ergosterol biosynthesis. The VdAHA1 knockout mutant strain also showed decreased melanin in microsclerotia by reduced expression of microsclerotia and melanin related genes Vaflm, Vayg1, and VdSCD. …”
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18317
Expression changes of metalloproteinase (MMP)-9 and tissue inhibitor of matrix metalloproteinase (TIMP)-1 in immunofluorescence (IF) staining.
Published 2024“…IF staining showed that MMP-9 expression was significantly increased in the model group. After treatment with QLQX or empagliflozin, the expression of MMP-9 significantly decreased. …”
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18318
Data Sheet 1_Differential regulation of soil microecology in crop rotation systems of maize, seed pumpkin, and processing tomato.docx
Published 2025“…Notably, the SLa treatment significantly decreased soil total potassium content by 13.6%. …”
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18319
Differences between reproductive and constructive uses during school lockdown and after the pandemic.
Published 2024“…<p>The figure shows that while learning activities significantly decreased after the pandemic, constructive learning activities remained virtually the same in both periods.…”
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18320
Analysis of errors of the AI model on accuracy and decision times for different tasks during the retrospective reader study. (a)
Published 2025“…When the AI model is correct, the explanation decreases decision time significantly, while it does not increase the decision time for incorrect decisions.…”