Showing 19,401 - 19,420 results of 21,342 for search '(( significant challenges decrease ) OR ( significant decrease decrease ))', query time: 0.55s Refine Results
  1. 19401

    Image_3_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG by Bin Zhang (64682)

    Published 2025
    “…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …”
  2. 19402

    Supplementary Material for: Seizure Burden Before and After Lidocaine as Add-on Therapy in (a)EEG-Confirmed Neonatal Seizures by figshare admin karger (2628495)

    Published 2025
    “…After LDC administration, median TSB decreased significantly from 31 (interquartile range, IQR 16–68) to 0 minutes (IQR 0–0, p<0.01), and MSB from 10 (IQR 6–41) to 0 min/hour (IQR 0–0, p<0.01). …”
  3. 19403

    Image 1_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.ti... by Junhyeok Choi (14078586)

    Published 2025
    “…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …”
  4. 19404

    Table 1_Effect of membrane rigidification on the BrAFP1 expression and cold-tolerance in Brassica rapa.docx by Xiaoyun Dong (9706099)

    Published 2025
    “…The expression levels of cold-responsive genes, including cyclic nucleotide-gated channel 1 (CNGC1), open stomata 1 (OST1), and inducer of CBF expression 1 (ICE1), as well as membrane fluidity-related genes, such as acyl-lipid desaturase 2 (ADS2), fatty acid desaturase 2 (FAD2), and sensitive to freezing 2 (SFR2), were significantly increased following DMSO pretreatment, while BA treatment significantly inhibited the expression of these genes. …”
  5. 19405

    Image 5_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.ti... by Junhyeok Choi (14078586)

    Published 2025
    “…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …”
  6. 19406

    Data Sheet 1_Lactobacillus paragasseri HM018 derived from breast milk ameliorates hyperlipidemia in high-cholesterol rats by modulating bile acid metabolism.docx by Chunyu Yao (13559263)

    Published 2025
    “…</p>Results and discussion<p>We established three dosage groups (2.5 × 10<sup>8</sup>, 5 × 10<sup>8</sup>, and 1.5 × 10<sup>9</sup> CFU/rat), demonstrating that HM018 significantly reduced high-fat diet-induced serum total cholesterol, triglycerides, and low-density lipoprotein cholesterol levels, while ameliorating gut microbiota dysbiosis and decreasing the Firmicutes/Bacteroidetes ratio. …”
  7. 19407

    The regulation of AsfR on tmRNA expression mediates bacterial motility and virulence in <i>aeromonas veronii</i> by Huimin Chang (12537320)

    Published 2025
    “…Consistently, the transcription level of tmRNA was significantly decreased in Δ<i>asfR</i> compared with WT of <i>A. veronii</i> by quantitative real-time PCR (RT-qPCR) analyses. …”
  8. 19408

    Data Sheet 1_Daily online adaptation enhances target coverage in prostate cancer radiotherapy: a retrospective analysis.pdf by Hanna Malygina (22545980)

    Published 2025
    “…Interquartile ranges decreased across all metrics.</p>Conclusions<p>Adaptation significantly improved target dose metrics compared to non-adapted plans, without compromising organs-at-risk sparing. …”
  9. 19409

    Modulating Aesthetic Furniture Preferences through Music: A Multimodal Neurophysiological Study Using Neural Ordinary Differential Equations Networks by Jiufang Lv (20807355)

    Published 2025
    “…</p><p dir="ltr">The findings revealed that musical intervention significantly modulated neural activity in specific frequency bands: prediction error for tactile density in the Alpha band decreased by 26.9%, while prediction accuracy for exquisiteness in the Beta band improved significantly. …”
  10. 19410

    DATA.xlsx by Zhichun Yang (21466757)

    Published 2025
    “…We found that total ecosystem <sup>15</sup>N recovery was significantly higher under UAN than CAN during early stages (7-120 days), although this difference diminished by 365 days. …”
  11. 19411

    Supporting information Abou-Kandil et al. by Olaf Kniemeyer (8561361)

    Published 2024
    “…Deletion of <i>rtaA</i> did not significantly change the ergosterol content of <i>A. fumigatus</i>, but decreased fluorescence intensity of the sterol-binding stain filipin. …”
  12. 19412

    Data Sheet 1_Diversity, functionality, and stability: shaping ecosystem multifunctionality in the successional sequences of alpine meadows and alpine steppes on the Qinghai-Tibet P... by Xin Jin (108988)

    Published 2025
    “…Surprisingly, community stability also significantly influences ecosystem multifunctionality—a factor rarely highlighted in previous studies. …”
  13. 19413

    Table 3_Outcomes after liposuction-based treatment of lymphedema: a systematic review and meta-analysis.docx by Junzhe Chen (5729912)

    Published 2025
    “…Combined approaches achieved slightly lower reductions (87.31%), but significantly decreased compression dependence, improved lymphatic function, and enhanced QOL. …”
  14. 19414

    Table 1_RfaH contributes to maximal colonization and full virulence of hypervirulent Klebsiella pneumoniae.docx by Yichuan Qiu (13302081)

    Published 2024
    “…We found that the ΔrfaH mutant led to a significantly decreased mortality of K. pneumoniae in a mouse intraperitoneal infection model. …”
  15. 19415

    Image 2_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.ti... by Junhyeok Choi (14078586)

    Published 2025
    “…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …”
  16. 19416

    Table 2_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.do... by Junhyeok Choi (14078586)

    Published 2025
    “…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …”
  17. 19417

    Supplementary Material for: Early initiation of icodextrin reduces peritoneal dialysis-associated peritonitis risk: a retrospective cohort study by Mitsuno R. (20394647)

    Published 2024
    “…The early use of ICO remained significantly associated with decreased incidence of both peritonitis and TI (hazards ratio [HR], 0.19; 95% confidence interval [CI], 0.06–0.69 and HR, 0.10; 95% CI, 0.01–0.78, respectively) using Cox regression analysis adjusted for potential confounders. …”
  18. 19418

    Table1_Astragaloside IV Alleviates Tacrolimus-Induced Chronic Nephrotoxicity via p62-Keap1-Nrf2 Pathway.DOCX by Ping Gao (172038)

    Published 2025
    “…Our results demonstrated that AS-IV significantly improved renal function and alleviated tubulointerstitial fibrosis compared with the model group. …”
  19. 19419

    Table1_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.docx by Eryun Zhang (20172057)

    Published 2024
    “…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …”
  20. 19420

    Table1_Astragaloside IV Alleviates Tacrolimus-Induced Chronic Nephrotoxicity via p62-Keap1-Nrf2 Pathway.DOCX by Ping Gao (172038)

    Published 2025
    “…Our results demonstrated that AS-IV significantly improved renal function and alleviated tubulointerstitial fibrosis compared with the model group. …”