Description of PTPRG genetic variants identified in a cohort of Chronic Myeloid Leukemia patients and their ability to influence response to Tyrosine kinase Inhibitors by Mohamed A. Ismail (418629)

“…Among them, five variants were identified in 15 resistant cases. Of these, one novel exon variant (c.1602_1603insC), c.841-29C>T (rs199917960) and c.1378-224A>G (rs2063204) were found to be significantly different between the resistant cases compared to responders. …”

Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity by Mohamed Abu-Farha (18535590)

“…In functional assays, our data indicated that ectopic expression of HDAC4 significantly impaired TNF-α-dependent activation of NF-κB, establishing thus a link between HDAC4 and regulation of the immune system. …”

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd... by Katherine R Paulson (8674293)

Dual-stage segmentation and classification framework for skin lesion analysis using deep neural network by Khadija Manzoor (22565369)

“…Early and accurate detection of such conditions is critical to prevent progression, especially in cases of malignant skin lesions. This study aims to develop a dual-stage deep learning framework for the segmentation and classification of skin lesions, addressing challenges such as imbalanced data, lesion variability, and low contrast.…”

Enhancing Curcumin’s therapeutic potential in cancer treatment through ultrasound mediated liposomal delivery by Radha, Remya

“…Improving the efficacy of chemotherapy remains a key challenge in cancer treatment, considering the low bioavailability, high cytotoxicity, and undesirable side effects of some clinical drugs. …”
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AI-Based Multiclass Grading of Hepatic Steatosis From B-Mode Ultrasound: Generalization Across Modalities and Clinical Comparison With Radiologists by Fahad Muflih Alshagathrh (18427950)

“…<p dir="ltr">Non-alcoholic fatty liver disease (NAFLD) is a growing public health challenge, underscoring the need for scalable, non-invasive tools to grade hepatic steatosis. …”