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441
Epigenetic analysis of Paget’s disease of bone identifies differentially methylated loci that predict disease status
منشور في 2021"…<p dir="ltr">Paget’s disease of bone (PDB) is characterized by focal increases in disorganized bone remodeling. This study aims to characterize PDB-associated changes in DNA methylation profiles in patients’ blood. …"
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442
SARS‐CoV‐2 omicron variant may present with severe sickle cell painful crisis: A report of two cases
منشور في 2023"…Currently, the virus had shown significant changes and mutations that resulted in the emergence of different strains. …"
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443
Osteoporosis: An under-recognized public health problem
منشور في 2016"…<p dir="ltr">Over 200 million people suffer from osteoporosis worldwide, which occurs when bone tissues become structurally deteriorated and bone mass becomes fragile, resulting in an increased risk of fracture. This review aims to describe the underlying risk factors and provide guidance on changes in lifestyle for those at risk of developing osteoporosis. …"
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444
Supporting secure dynamic alert zones using searchable encryption and graph embedding
منشور في 2023"…Furthermore, we investigate the more challenging case of dynamic alert zones, where the area of interest changes over time. Our extensive experimental evaluation shows that our solutions can significantly improve computational overhead compared to existing baselines.…"
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445
Beyond genetics: Exploring the role of epigenetic alterations in breast cancer
منشور في 2024"…Its rising incidence is attributed to factors such as delayed diagnosis, the complexity of its subtypes, and increasing drug resistance, all contributing to less-than-ideal patient outcomes. …"
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446
Assessment of Inventory and Transportation Collaboration in a Logistics Marketplace
منشور في 2020احصل على النص الكامل
doctoralThesis -
447
Coevolving residues distant from the ligand binding site are involved in GAF domain function
منشور في 2025"…Mutational incorporation into a Bioluminescence Resonance Energy Transfer (BRET)-based biosensors, which detects ligand-induced conformational changes, showed altered GAF domain conformation and increased EC50 for cGMP-induced conformational changes. …"
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448
Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy
منشور في 2021"…The complex and dynamic interactions of the secreted cytokines, chemokines, growth factors, and their receptors mediate chronic inflammation and immunosuppressive TME favoring tumor progression, metastasis, and decreased response to therapy. The molecular changes in the TME are used as biological markers for diagnosis, prognosis, and response to treatment in patients. …"
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449
Functional Connectivity Analysis under Vigilance Decrement and Enhanced Mental States
منشور في 2020احصل على النص الكامل
doctoralThesis -
450
Enhancing the quality of lentil proteins via combination with whey proteins based on a dual process: a novel strategy through the incorporation of complexation and fermentation
منشور في 2024"…The FTIR spectrophotometer scans indicated significant (<i>P</i> < 0.05) changes to the secondary protein structure components (random coil and α-helix). …"
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451
Interactions of black carrot concentrate powder as a natural coloring agent with gelatine and sucrose in model gummy samples
منشور في 2025"…With growing consumer concerns about the sustainability and safety of synthetic food colorings, the food industry is increasingly turning to natural colorants derived from plants. …"
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452
Pathways to learning: exploring the impact of augmented reality on vocabulary development in children with autism spectrum disorder
منشور في 2025"…Results revealed substantial individual variability, with some participants exhibiting significant improvements in vocabulary learning performance during the intervention and maintenance phases, as evidenced by increased correct responses and high PEM values. …"
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453
Seizure-like behavior and hyperactivity in <i>napb</i> knockout zebrafish as a model for autism and epilepsy
منشور في 2025"…We observed that napb crispants (CR) show shorter motor neuron axons length together with altered locomotion behavior, including significant increases in larvae total distance traveled, swimming velocity, and rotation frequency, indicating that these behavioral changes effectively mimic the human epileptic phenotype. …"
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454
COVID-19 biomarkers for severity mapped to polycystic ovary syndrome
منشور في 2020"…These protein panels target biological processes involved in vessel damage, platelet degranulation, the coagulation cascade and the acute phase response [1], with greater protein changes dependent on the COVID-19 severity. However, it is observed that in metabolic conditions such as polycystic ovary syndrome expressed proteins differ compared to control women [2] and PCOS patients have increased platelet aggregation and decreased plasma fibrinolytic activity, resulting in a prothrombotic propensity [3, 4], with elevated coagulation markers [5]. …"
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455
Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
منشور في 2021"…</p><h3>Results</h3><p dir="ltr">All countries displayed over a 40-fold difference in HIV mortality between municipalities with the highest and lowest age-standardized HIV mortality rate in the last year of study for men, and over a 20-fold difference for women. Despite decreases in national HIV mortality in all countries—apart from Ecuador—across the period of study, we found broad variation in relative changes in HIV mortality at the municipality level and increasing relative inequality over time in all countries. …"
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456
The landscape of PreK-12 engineering online resources for teachers
منشور في 2015"…Introducing engineering at the Prekindergarten through 12th grade (PreK-12) education level requires significant changes in teacher preparation and support. …"
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article -
457
Modification and Glycation Microalgae Proteins by Non-Thermal Assisted Process
منشور في 2024"…However, it is crucial that these processes result in only the targeted changes in protein structures with minimal heat and chemical usage. …"
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458
A review of Soil and Water Assessment Tool (SWAT) studies of Mediterranean catchments: Applications, feasibility, and future directions
منشور في 2023"…A total of 260 articles have been identified since the earliest documented use of the model in a Mediterranean catchment back in 2002; of which 62% were carried out in Greece, Italy, or Spain. SWAT applications increased significantly in recent years since 86% of the reviewed papers were published in the past decade. …"
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459
The effect of doping MoSe<sub>2</sub> by clusters of noble metals on its adsorption for NH<sub>3</sub>
منشور في 2022"…When compared to the pristine structure, the doped MoSe<sub>2</sub> structures reveal significant changes in electronic characteristics that are reflected on the DOS and band structures. …"
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460