Table4_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx by Yifang He (18126257)

“…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…”

Image 4_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tif by Matthew C. Austin (20633168)

“…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …”

Table1_Genetic variants of LRRC8C, OAS2, and CCL25 in the T cell exhaustion-related genes are associated with non-small cell lung cancer survival.docx by Guojun Lu (7169969)

“…Background<p>T cell exhaustion is a state in which T cells become dysfunctional and is associated with a decreased efficacy of immune checkpoint inhibitors. …”

Image2_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.tif by Yifang He (18126257)

“…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…”

Table 1_Prior Trichinella spiralis infection protects against Schistosoma mansoni induced hepatic fibrosis.docx by Asmaa M. El-kady (16502930)

“…Furthermore, pre- infection with T. spiralis markedly reduced S. mansoni- induced hepatic fibrosis, as evidenced by decreased collagen deposition, low expression of α-SMA, and significantly reduced levels of IL-17, IL-1B, IL-6, TGF-B, IL-23, and TNF-α compared to mice infected with S. mansoni only.…”

Table 1_Regulation effect of seed priming on sowing rate of direct seeding of rice under salt stress.pdf by Yicheng Zhang (790286)

“…Our results demonstrated that under T1–T3, the germination rate, α-amylase activity, and soluble sugar and protein contents were significantly increased after priming treatments. The contents of reactive oxygen species (i.e., O₂⁻ and H₂O₂) and malondialdehyde (MDA) were decreased, while the activities of enzymatic antioxidants (i.e., superoxide dismutase, peroxidase, and catalase) and the K⁺/Na⁺ ratio of rice were significantly increased after the above seed priming treatments. …”

Image 2_Kidney sparing surgery versus radical nephroureterectomy in upper tract urothelial carcinoma: a meta-analysis and systematic review.tif by Leqing Zhou (20981021)

“…In the comparison between the endoscopic management (EM) and RNU groups, EM was associated with worse overall survival outcomes (HR,1.40; 95%CI,1.08-1.82; P=0.01) based on multivariable Cox regression analysis, and the upper tract recurrence rate (OR,39.06; 95%CI, 14.55-104.85; P<0.00001) was significantly higher in the EM group. On the other hand, in patients treated with KSS, postoperative renal function as measured by eGFR increased by 0.4ml/min/1.73 m², while it decreased by 11.4ml/min/1.73 m² in the RNU group (WMD, 11.81 ml/min/1.73 m²; 95%CI,9.06-14.56; P<0.0001).…”

Image 2_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …”

Data Sheet 1_Association of MIF rs1007888 and ARAP1 rs1552224 genetic variants with the risk of gestational diabetes mellitus in a chinese population; case study and meta-analysis.... by Yuxuan Zhang (1425721)

“…ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. …”

Supplementary Material for: Head positioning for stroke blood flow augmentation assisting reperfusion therapies (HEAD-START) study by figshare admin karger (2628495)

“…Trendelenburg positioning was maintained for 24h if lesion volume significantly decreased (≥5mL) and stroke reperfusion was suboptimal or undetermined. …”

Data Sheet 4_Unilateral biportal endoscopic transforaminal lumbar interbody fusion versus minimally invasive transforaminal lumbar interbody fusion for single-level lumbar spondylo... by Yu Zhang (12946)

“…Compared with MIS-TLIF, ULIF demonstrated significantly reduced intraoperative blood loss [WMD = −35.71, 95% CI (−51.80, −19.63), p < 0.01], fewer intraoperative fluoroscopy times [WMD = −1.29, 95% CI (−2.56, −0.02), p < 0.05], lower postoperative drainage volume [WMD = −20.64, 95% CI (−37.13, −4.15), p = 0.01], shorter postoperative ambulation time [WMD = −0.30, 95% CI (−0.42, −0.17), p < 0.01], and decreased hospital stay duration [WMD = −1.50, 95% CI (−2.09, −0.90), p < 0.01]. …”

Data Sheet 1_Hypocomplementemia dynamics during tocilizumab therapy in systemic juvenile idiopathic arthritis: a retrospective longitudinal study.xlsx by Jiayun Ling (15249289)

“…Notably, C3 remained significantly correlated at week 48 (r = 0.513, P = 0.025). …”

Table 1_Optimal fertilizer rate and sowing density can improve oat quality, yield and N and P comprehensive efficiency in the Loess Plateau of China.docx by Ruochen Zhang (3434996)

“…The results of correlation analysis revealed significant positive correlations (P< 0.05) of forage yield and CP with nutrients efficiency of oat, but negative correlations with fiber content.…”

Data Sheet 3_Unilateral biportal endoscopic transforaminal lumbar interbody fusion versus minimally invasive transforaminal lumbar interbody fusion for single-level lumbar spondylo... by Yu Zhang (12946)

“…Compared with MIS-TLIF, ULIF demonstrated significantly reduced intraoperative blood loss [WMD = −35.71, 95% CI (−51.80, −19.63), p < 0.01], fewer intraoperative fluoroscopy times [WMD = −1.29, 95% CI (−2.56, −0.02), p < 0.05], lower postoperative drainage volume [WMD = −20.64, 95% CI (−37.13, −4.15), p = 0.01], shorter postoperative ambulation time [WMD = −0.30, 95% CI (−0.42, −0.17), p < 0.01], and decreased hospital stay duration [WMD = −1.50, 95% CI (−2.09, −0.90), p < 0.01]. …”

Table 1_Complex evaluation of coagulation, fibrinolysis, and inflammatory cytokines in SARS-CoV-2 infected pregnant women: a prospective, case-control study.docx by Zsuzsa Bagoly (429210)

“…Admission IL-1β, and IL-33 were significantly lower, while IL-18 was significantly higher in cases when COVID-19 became more severe, along with significantly decreased FVIII, FXIII and plasminogen. …”

Supplementary file 1_Interspecific association characteristics of Alternanthera philoxeroides-invaded communities and their latitudinal variations.docx by Hao Wu (65943)

“…The association intensity between terrestrial accompanying species significantly decreased with increasing latitude, and the association intensity between aquatic accompanying species varied weakly along the latitudinal gradient. …”

Data Sheet 4_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent g... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

Data Sheet 5_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent g... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

Data Sheet 1_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent g... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

Data Sheet 3_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent g... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”