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significant change » significant changes (Expand Search), significant challenge (Expand Search)
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58041
Data_Sheet_3_Circulating exo-miR-154-5p regulates vascular dementia through endothelial progenitor cell-mediated angiogenesis.DOCX
Published 2022“…Background<p>Vascular dementia (VaD) mainly results from cerebral vascular lesions and tissue changes, which contribute to neurodegenerative processes. …”
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58042
Data Sheet 4_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf
Published 2025“…</p>Results<p>YQHX improved cardiac function and attenuated pathological changes in vivo. It ameliorated MAMs ultrastructure and function, enhancing CypD, MCU, Sig-1R, and NOGO-B expression while reducing IP3R2, GRP75, and VDAC1. in vitro, YQHX significantly increased viability, reduced oxygen-glucose deprivation-induced mPTP opening and Ca<sup>2+</sup> levels, upregulated CypD, MCU, Sig-1R, and NOGO-B, and downregulated IP3R2, GRP75, and VDAC1. …”
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58043
Supplementary file 1_The fibrin-derived peptide FX06 protects human pulmonary endothelial cells against the COVID-19-triggered cytokine storm.docx
Published 2025“…This deleterious effect was significantly reduced by FX06. FX06 was also shown to mitigate the cytotoxic activity of allogeneic CD8<sup>+</sup> T cells, which increased upon cytokine treatment. …”
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58044
Table_5_Transcriptome analysis provides insight into the regulatory mechanisms underlying pollen germination recovery at normal high ambient temperature in wild banana (Musa itiner...
Published 2023“…The cysteine content, free fatty acid (FFA) content, H<sub>2</sub>O<sub>2</sub> content, fructose content, and sucrose content of pollen were increased at treatment of 28°C, while D-Golactose content was decreased. …”
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58045
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58046
Table_4_Transcriptome analysis provides insight into the regulatory mechanisms underlying pollen germination recovery at normal high ambient temperature in wild banana (Musa itiner...
Published 2023“…The cysteine content, free fatty acid (FFA) content, H<sub>2</sub>O<sub>2</sub> content, fructose content, and sucrose content of pollen were increased at treatment of 28°C, while D-Golactose content was decreased. …”
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58047
Supplementary file 2_The fibrin-derived peptide FX06 protects human pulmonary endothelial cells against the COVID-19-triggered cytokine storm.pptx
Published 2025“…This deleterious effect was significantly reduced by FX06. FX06 was also shown to mitigate the cytotoxic activity of allogeneic CD8<sup>+</sup> T cells, which increased upon cytokine treatment. …”
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58048
Table_1_Screening of co-pathogenic genes of non-alcoholic fatty liver disease and hepatocellular carcinoma.docx
Published 2022“…However, its carcinogenic mechanism is still unclear, looking for both diseases’ transcriptome levels, the same changes as we are looking for NAFLD may provide a potential mechanism of action of HCC. …”
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58049
Image 1_Evaluation of the relationship between cytochrome P450 (CYP) 1A2 gene copy number variation and CYP1A2 protein content and enzyme activity in canine liver.jpeg
Published 2025“…Additionally, a genetic polymorphism (stop codon) has been identified which results in the expression of an inactive protein, this has been investigated and changes in the pharmacokinetics of some clinically used drugs have been described. …”
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58050
Data_Sheet_4_Circulating exo-miR-154-5p regulates vascular dementia through endothelial progenitor cell-mediated angiogenesis.XLSX
Published 2022“…Background<p>Vascular dementia (VaD) mainly results from cerebral vascular lesions and tissue changes, which contribute to neurodegenerative processes. …”
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58051
Data Sheet 2_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip
Published 2025“…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”
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58052
Analysis of <i>n</i>(<sup>87</sup>Sr)/<i>n</i>(<sup>86</sup>Sr), <i>δ</i><sup>88</sup>Sr/<sup>86</sup>Sr<sub>SRM987</sub> and elemental pattern to characterise groundwater and rech...
Published 2019“…The <i>n</i>(<sup>87</sup>Sr)/<i>n</i>(<sup>86</sup>Sr) ratio and elemental pattern changed with aquifer depth as a result of progressing bedrock leaching and dissolution with increasing groundwater residence time. …”
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58053
Table_8_Transcriptome analysis provides insight into the regulatory mechanisms underlying pollen germination recovery at normal high ambient temperature in wild banana (Musa itiner...
Published 2023“…The cysteine content, free fatty acid (FFA) content, H<sub>2</sub>O<sub>2</sub> content, fructose content, and sucrose content of pollen were increased at treatment of 28°C, while D-Golactose content was decreased. …”
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58054
Table 1_Evaluation of the relationship between cytochrome P450 (CYP) 1A2 gene copy number variation and CYP1A2 protein content and enzyme activity in canine liver.docx
Published 2025“…Additionally, a genetic polymorphism (stop codon) has been identified which results in the expression of an inactive protein, this has been investigated and changes in the pharmacokinetics of some clinically used drugs have been described. …”
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58055
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58056
Data Sheet 3_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf
Published 2025“…</p>Results<p>YQHX improved cardiac function and attenuated pathological changes in vivo. It ameliorated MAMs ultrastructure and function, enhancing CypD, MCU, Sig-1R, and NOGO-B expression while reducing IP3R2, GRP75, and VDAC1. in vitro, YQHX significantly increased viability, reduced oxygen-glucose deprivation-induced mPTP opening and Ca<sup>2+</sup> levels, upregulated CypD, MCU, Sig-1R, and NOGO-B, and downregulated IP3R2, GRP75, and VDAC1. …”
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58057
CD11b<sup>+</sup> CD11c<sup>high</sup> cell activation during <i>L</i>. <i>infantum</i> infection is enhanced in TLR4-deficient mice.
Published 2020“…(F) Heat map representing the relative fold changes in the expression levels of TLR-induced genes normalized to that of β-actin; the genes are clustered by distance (hclust, gplot from R package). …”
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58058
DataSheet2_GPX4 Plays a Crucial Role in Fuzheng Kang’ai Decoction-Induced Non-Small Cell Lung Cancer Cell Ferroptosis.docx
Published 2022“…Moreover, characteristic morphological changes of NSCLC cell ferroptosis was observed under transmission electron microscopy. …”
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58059
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58060
Image 8_The fibrin-derived peptide FX06 protects human pulmonary endothelial cells against the COVID-19-triggered cytokine storm.jpeg
Published 2025“…This deleterious effect was significantly reduced by FX06. FX06 was also shown to mitigate the cytotoxic activity of allogeneic CD8<sup>+</sup> T cells, which increased upon cytokine treatment. …”