Table6_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... حسب Huijing Ren (19986303)

"…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …"

Image 3_Loss of calcium/calmodulin-dependent protein kinase kinase 2, transferrin, and transferrin receptor proteins in the temporal cortex of Alzheimer’s patients postmortem is as... حسب Mohammad Golam Sabbir (15874493)

"…</p>Results<p>CAMKK2, TF, and TFRC levels were significantly decreased in AD patients’ temporal cortices compared to CN individuals, independent of age or postmortem interval-related changes. …"

DataSheet1_Updated evidence of the Naoshuantong capsule against ischemic stroke: a systematic review and meta-analysis of randomized controlled trials.docx حسب Cuilin Que (19743256)

"…Background<p>Stroke is a serious health issue that can result in death or disability, leading to a significant economic strain on society and families. …"

Data Sheet 1_Visual attention during non-immersive virtual reality balance training in older adults with mild to moderate cognitive impairment: an eye-tracking study.pdf حسب Marcos Maldonado-Díaz (11221102)

"…Further studies with larger samples are needed to confirm these preliminary findings.…"

Image 1_Safety profile and efficacy of secukinumab in the treatment of autoimmune myasthenia gravis: a single-center retrospective study.jpeg حسب Shuangmei Zhang (1807303)

"…Limitations include small sample size and retrospective design, warranting validation in larger randomized trials.</p>…"

Data and code from: Limited responses of lizard assemblages to experimental fire regimes in an Australian tropical savanna حسب angga rachmansah (22007819)

"…The abundance of only one of the five most common species was significantly related to fire frequency. Species richness decreased with increased fire frequency and showed a humped relationship with woody cover. …"

Data Sheet 1_Safety profile and efficacy of secukinumab in the treatment of autoimmune myasthenia gravis: a single-center retrospective study.pdf حسب Shuangmei Zhang (1807303)

"…Limitations include small sample size and retrospective design, warranting validation in larger randomized trials.</p>…"

Table 1_Global, regional, and national esophageal cancer deaths and DALYs attributable to diet low in vegetables and fruits, 1990–2019: analysis for the global burden of disease st... حسب Bing Cui (179696)

"…Decomposition analysis quantified the contributions of aging, population dynamics, and epidemiological changes to deaths and disability-adjusted life years (DALYs). …"

Protocol for our RNA-seq. حسب Sabih Rashid (5618807)

"…B) Volcano plots depicting the spread of gene expression changes between <i>aak(0); hzl-1 and aak(0)</i> dauer and post-dauer (PD) animals. …"

Table 1_Global, regional, and national burden of myocarditis and its attributable risk factors in 204 countries and territories from 1990 to 2021: updated systematic analysis.docx حسب Jiajia Ren (11151738)

"…Concurrently, the age-standardized prevalence rate (ASPR) per 100,000 people also saw a slight increase (no statistical significance) from 6.35 (5.37 to 7.36) to 6.41 (5.48 to 7.44). …"

Image1_Efficacy and Safety of a Polysaccharide-Based Natural Substance Complex in the Treatment of Obesity and Other Metabolic Syndrome Components: A Systematic Review.TIF حسب Giuseppina Guarino (6795282)

"…At present, the only approved treatments for MetS are dietary changes and physical activity, which are associated with a high rate of non-compliance. …"

Image 1_Fraxin modulates lipid metabolism as well as gut flora to avert NAFLD.tif حسب Yang Jing (2231179)

"…GO and KEGG analyses suggested that fraxin primarily treats NAFLD by modulating lipid metabolism and atherosclerosis-related signaling pathways. In vivo, fraxin significantly lowered liver index and visceral fat accumulation, reduced serum levels of “interleukin-6 (IL-6),” “aspartate aminotransferase,” “tumor necrosis factor-α (TNF-α)” and “alanine aminotransferase,” and decreased hepatic TG content. …"

Data Sheet 1_Influence of age-adjusted shock index trajectories on 30-day mortality for critical patients with septic shock.zip حسب Suru Yue (12194255)

"…The latent category trajectory model (LCTM) classified ASI changes within 24 h of intensive care unit (ICU) admission. …"

Table 1_LncRNA NEAT1 promotes epithelial–mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis.docx حسب Shuman Li (652613)

"…</p>Results<p>In comparison to controls, NEAT1 expression was significantly elevated in the epithelial tissues of CRSwNP. …"

Table 2_LncRNA NEAT1 promotes epithelial–mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis.docx حسب Shuman Li (652613)

"…</p>Results<p>In comparison to controls, NEAT1 expression was significantly elevated in the epithelial tissues of CRSwNP. …"

Image1_Characterization of GABAergic marker expression in prefrontal cortex in dexamethasone induced depression/anxiety model.jpeg حسب Ling Hu (374570)

"…Background<p>The pivotal responsibility of GABAergic interneurons is inhibitory neurotransmission; in this way, their significance lies in regulating the maintenance of excitation/inhibition (E/I) balance in cortical circuits. …"

Figure 6 from Distant Metastases of Breast Cancer Resemble Primary Tumors in Cancer Cell Composition but Differ in Immune Cell Phenotypes حسب Laura Kuett (20493991)

"…<b>F</b> and <b>G,</b> Immune cell phenotypic cluster enrichment in each clinical breast cancer subtype (<b>F</b>) or metastasis-defined patient group (<b>G</b>) at metastatic sites compared with average metastasis composition by differential abundance testing. Circles display significantly enriched (red) or decreased (blue; FDR < 0.05; multiple testing correction with the Benjamin–Hochberg method) results, with size indicating the log-transformed fold change.  …"

Supplementary file 1_Effect of Bifidobacterium longum subsp. infantis YLGB-1496 on common diseases in pediatrics: a randomized, blinded, placebo-controlled trial.docx حسب Xi Zhang (83736)

"…</p>Conclusion<p>Daily administration of YLGB-1496 at a dosage of 1.5 × 10¹⁰ CFU for 3 months significantly reduced the episodes of cough, fever, dry stool (defined as Bristol stool scale type 1–3), and eczematous changes of the skin. …"

Image 2_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff حسب Juliana R. Zampieri (22261441)

"…While p35 was important for antigen processing by M0 and M2, M1 were able to maintain capacity to process antigen albeit with a reduction due to decreased stability of peptide: MHC II complex.</p>Conclusion<p>While loss of p35 resulted in minor changes in phenotype, there were decreases in ARG-1 production and STAT3 phosphorylation, increased metabolism, and dramatically reduced antigen processing by M0, M1 or M2. …"

Data Sheet 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.docx حسب Lillia A. Baird (10575941)

"…Peripheral NK and CD8+ T cells were decreased dose-dependently. Interestingly, spinal cord infiltrating NK cells increased with low-dose tofacitinib, though no other changes in neuroinflammation were observed. …"