يعرض 5,281 - 5,300 نتائج من 6,756 نتيجة بحث عن '(( significant changes decrease ) OR ( significant ((changes decrease) OR (largest decrease)) ))', وقت الاستعلام: 0.52s تنقيح النتائج
  1. 5281

    Table 1_Xianyu capsule ameliorates neuroinflammatory and glycerophospholipid metabolism in lithium-pilocarpine-induced acute epilepsy.docx حسب Dongsheng Yu (521989)

    منشور في 2025
    "…</p>Results<p>XYC administration ameliorated the pathological changes and neurons apoptosis of brain hippocampus CA1 region, with reduced MDA and increased SOD and CAT levels in hippocampus, and decreased inflammation cytokine in serum. 16S rDNA sequencing revealed distinct gut microbial restructuring in XYC-treated epileptic models, characterized by phylum-level alterations in lipid-associated taxa (Tenericutes, Patescibacteria, Epsilonbacteraeota, Proteobacteria) and genus-level modulations (Lactobacillus, Ramboutsia, Staphylococcus). …"
  2. 5282

    Table 1_Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19.docx حسب Giuseppe G. F. Leite (18186056)

    منشور في 2024
    "…<p>The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). …"
  3. 5283

    Data Sheet 6_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... حسب Ying-han Deng (21604157)

    منشور في 2025
    "…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…"
  4. 5284

    Image 3_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif حسب Inssaf Berkiks (15350248)

    منشور في 2025
    "…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …"
  5. 5285

    <b>Differential Effects of Retinol-Binding Protein 3 and Anti-VEGF Antibodies on Retinal Dysfunctions in Diabetic Retinopathy</b> حسب Qin Li (36669)

    منشور في 2025
    "…<p dir="ltr">Anti-vascular endothelial growth factor (anti-VEGF) therapies are effective treatment of severe diabetic retinopathy (DR) and macular edema, but a significant subset of people showed inadequate response to anti-VEGF intervention. …"
  6. 5286

    Data_Sheet_1_Effects of stand age and soil microbial communities on soil respiration throughout the growth cycle of poplar plantations in northeastern China.pdf حسب Xiangrong Liu (380124)

    منشور في 2024
    "…Bacterial and fungal communities differed significantly in abundance, composition, and function, with the Litter C/N ratio being a key variable affected by microbial community changes.…"
  7. 5287

    Supplementary file 1_Assessment of suitability evaluation for Ficus altissima blume ancient trees in different climatic environments in Guangxi, China.docx حسب Hongliang Gu (21671054)

    منشور في 2025
    "…Introduction<p>The Guangxi Zhuang Autonomous Region of China is home to numerous Ficus altissima Blume (F. altissima) ancient trees over 300 years old, which hold significant cultural, ecological, and scientific research value. …"
  8. 5288

    Table 3_Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19.xlsx حسب Giuseppe G. F. Leite (18186056)

    منشور في 2024
    "…<p>The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). …"
  9. 5289

    Image 5_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tiff حسب Inssaf Berkiks (15350248)

    منشور في 2025
    "…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …"
  10. 5290

    Image 1_Exercise intolerance in patients with chronic coronary syndrome: insights from exercise stress echocardiography.tiff حسب Wei-wei Zhu (20349897)

    منشور في 2024
    "…</p>Conclusion<p>Hemodynamic changes during exercise in CCS patients were effectively evaluated using ESE. …"
  11. 5291

    Data Sheet 8_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... حسب Ying-han Deng (21604157)

    منشور في 2025
    "…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…"
  12. 5292

    Table 2_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx حسب Zhenyu Zhao (737165)

    منشور في 2025
    "…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"
  13. 5293

    Image 2_Exercise intolerance in patients with chronic coronary syndrome: insights from exercise stress echocardiography.tiff حسب Wei-wei Zhu (20349897)

    منشور في 2024
    "…</p>Conclusion<p>Hemodynamic changes during exercise in CCS patients were effectively evaluated using ESE. …"
  14. 5294

    Assessment of soil erosion risks and prioritizing nature-based conservation practices using RUSLE, geospatial techniques and household surveys in central Ethiopia حسب Gamachu Yadata Nugusa (22683061)

    منشور في 2025
    "…<p>Land use and land cover changes (LULCC) have aggravated catchment degradation, threatening socio-ecohydrological services (SEHSs). …"
  15. 5295

    Alterations in gut microbiota and plasma metabolites in patients with generalized anxiety disorder: a multi-omics study حسب Yi Li (1144)

    منشور في 2025
    "…Notably, microbiome–metabolome combined analysis revealed a significant correlation between intestinal flora disorders and changes in the plasma metabolic profile. …"
  16. 5296

    Table 3_Integrative physiological, biochemical, and metabolomic analyses reveal complex drought and zinc stress tolerance in a novel Miscanthus hybrid.xlsx حسب Monirul Islam (283000)

    منشور في 2025
    "…Fatty acid derivatives, nitrogen-containing compounds, hormone/signal-related compounds (jasmonate), and secondary metabolites (phenylpropanoids, N-containing compounds, and terpenes) showed significant (p < 0.05) abundance changes in response to D, Zn, and its combination D + Zn stress. …"
  17. 5297

    Data Sheet 2_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... حسب Ying-han Deng (21604157)

    منشور في 2025
    "…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…"
  18. 5298

    Image 1_Biometric parameters and choroidal microstructure in Chinese children with unilateral anisometropia.pdf حسب Jing Wen (25059)

    منشور في 2025
    "…The CVI decreases as hyperopia progresses to emmetropia and then to myopia, indicating that choroidal vascularity changes during refractive development.…"
  19. 5299

    Data Sheet 1_Temperature influences mood: evidence from 11 years of Baidu index data in Chinese provincial capitals.csv حسب Mengjiao Yin (10995604)

    منشور في 2025
    "…Introduction<p>This study explores the dynamic relationship between temperature changes and public negative emotions—specifically depression, anxiety, and loneliness. …"
  20. 5300

    Table 3_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.xlsx حسب Zhenyu Zhao (737165)

    منشور في 2025
    "…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…"