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significant changes » significant challenge (Expand Search)
changes decrease » larger decrease (Expand Search), change increases (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
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5581
Table1_Endovascular treatment of aortic coarctation using covered balloon-expandable stents—a systematic review and meta-analysis.pdf
Published 2024“…The estimated pooled procedural success rate was 100% [95% confidence interval (CI): 98%–100%, I2 = 0, P = 0.78]. Significant decreases in trans-coarctation PGs and SBP were observed. …”
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5582
Table 5_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx
Published 2025“…Cluster analysis revealed significant changes in gene expression patterns: DEGs associated with mitochondrial function [including oxidative phosphorylation and citrate cycle (TCA cycle) pathways] were down-regulated, while most DEGs involved in glutathione metabolism were up-regulated. …”
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5583
Data Sheet 1_Microbial dysbiosis in obstructive sleep apnea: a systematic review and meta-analysis.docx
Published 2025“…</p>Conclusion<p>Patients with OSA exhibit reduced diversity, changes in bacterial abundance, and altered structure in the microbiota, especially in the gut microbiota. …”
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5584
Image 1_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif
Published 2025“…Cluster analysis revealed significant changes in gene expression patterns: DEGs associated with mitochondrial function [including oxidative phosphorylation and citrate cycle (TCA cycle) pathways] were down-regulated, while most DEGs involved in glutathione metabolism were up-regulated. …”
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5585
Table 3_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair...
Published 2025“…<p>In both humans and mice, obesity is often associated with peripheral and central inflammation, which can lead to diabetes, dysregulation of the stress response, changes in affective behavior, and memory impairment. …”
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5586
Table 5_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair...
Published 2025“…<p>In both humans and mice, obesity is often associated with peripheral and central inflammation, which can lead to diabetes, dysregulation of the stress response, changes in affective behavior, and memory impairment. …”
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5587
Table 1_Impact of different 3D regions of interest on quantifying dynamic lumbar vertebral microstructure in ovariectomized rats—a micro-CT study.doc
Published 2025“…</p>Results<p>The results indicated that the Tb.N of baseline group rats for ROI 1 was significantly lower than that for ROI 2. The Tb.Th of rats of the Sham 12w and Sham 24w groups was significantly increased compared to that of the baseline group rats using the ROI 2 analysis. …”
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5588
SEAwise Report on improved predictive models of recruitment under different habitat scenarios and incorporating experimental results
Published 2025“…Projections show no relevant changes in herring recruitment under RCP4.5 and a decreasing trend under RCP8.5. …”
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5589
Table 1_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx
Published 2025“…</p>Result<p>There was an increase in the number of traumatic amputations globally in 2021 compared to 1990. However, the change in age-standardized rates from 1990 to 2021 declined significantly. …”
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5590
Data Sheet 1_Diversity, functionality, and stability: shaping ecosystem multifunctionality in the successional sequences of alpine meadows and alpine steppes on the Qinghai-Tibet P...
Published 2025“…We further identify the primary environmental drivers of these changes and evaluate their collective impact on ecosystem multifunctionality. …”
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5591
Table 4_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx
Published 2025“…</p>Result<p>There was an increase in the number of traumatic amputations globally in 2021 compared to 1990. However, the change in age-standardized rates from 1990 to 2021 declined significantly. …”
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5592
Table 3_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx
Published 2025“…</p>Result<p>There was an increase in the number of traumatic amputations globally in 2021 compared to 1990. However, the change in age-standardized rates from 1990 to 2021 declined significantly. …”
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5593
Table 2_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx
Published 2025“…</p>Result<p>There was an increase in the number of traumatic amputations globally in 2021 compared to 1990. However, the change in age-standardized rates from 1990 to 2021 declined significantly. …”
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5594
Table 5_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx
Published 2025“…</p>Result<p>There was an increase in the number of traumatic amputations globally in 2021 compared to 1990. However, the change in age-standardized rates from 1990 to 2021 declined significantly. …”
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5595
Global maximum GPP from 2001-2018
Published 2025“…The GPPmax significantly increased in western North America, northern Europe, and eastern China, but decreased in tropical regions. …”
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5596
Table 6_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx
Published 2025“…</p>Result<p>There was an increase in the number of traumatic amputations globally in 2021 compared to 1990. However, the change in age-standardized rates from 1990 to 2021 declined significantly. …”
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5597
Data Sheet 1_Clinical pharmacist interventions in medication review for medication optimization in older hospitalized adults with mental disorders and somatic comorbidities: eviden...
Published 2025“…The number of PIMs also significantly decreased (p < 0.001), with reductions of 29.5% (from 308 to 217) based on the Priscus List and 17.5% (from 343 to 283) according to the Beers Criteria. …”
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5598
DataSheet2_α-Mangostin Alleviated Inflammation in Rats With Adjuvant-Induced Arthritis by Disrupting Adipocytes-Mediated Metabolism-Immune Feedback.PDF
Published 2025“…Generally, MAN restored the impaired fat anabolism in AIA rats, indicated by increased fat reservoir, leptin and adiponectin secretion, and PPAR-γ and SCD-1 expression. Meanwhile, it decreased circulating IL-1β and IL-6 levels, restored serological lipid profile changes, and relieved oxidative stresses, demonstrating potent therapeutic effects on AIA. …”
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5599
DataSheet1_α-Mangostin Alleviated Inflammation in Rats With Adjuvant-Induced Arthritis by Disrupting Adipocytes-Mediated Metabolism-Immune Feedback.PDF
Published 2025“…Generally, MAN restored the impaired fat anabolism in AIA rats, indicated by increased fat reservoir, leptin and adiponectin secretion, and PPAR-γ and SCD-1 expression. Meanwhile, it decreased circulating IL-1β and IL-6 levels, restored serological lipid profile changes, and relieved oxidative stresses, demonstrating potent therapeutic effects on AIA. …”
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5600
Supplementary file 1_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burd...
Published 2025“…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …”