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significant changes » significant challenge (Expand Search)
changes decrease » larger decrease (Expand Search), change increases (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
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5921
Table 1_Gandouling ameliorates Wilson’s disease-associated liver fibrosis in mice with associated faecal microbiome and metabolome remodeling.xlsx
Published 2025“…Introduction<p>Individuals with Wilson's disease (WD) exhibit liver fibrosis, a basic pathological change that was recently demonstrated to be dynamic and reversible. …”
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5922
Data Sheet 1_Membrane filtration reduces nutrient availability and invasion potential in drinking water systems, without affecting mature biofilms.docx
Published 2025“…Despite these differences in the bulk water, the mature biofilm community (~2 years old) remained stable, underscoring it resilience to changes in nutrient conditions. An invasion assay demonstrated that decay rates of unwanted microorganisms increased with decreasing organic carbon content. …”
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5923
Ameliorative impact of Juniperus Macrocarpa extract on methotrexate-induced hepatic damage in rats
Published 2025“…Juniperus macrocarpa also significantly boosted levels of the antioxidant enzymes, including SOD and GPX. …”
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5924
Glucose-6-phosphatase catalytic subunit 3 enhances host resistance to porcine epidemic diarrhea virus through regulating glycolysis/gluconeogenesis
Published 2025“…Notably, glucose-6-phosphatase catalytic subunit 3 (<i>G6PC3</i>) expression was significantly higher in Chinese Min piglets than in Yorkshire piglets. …”
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5925
Data Sheet 1_Study on the structure-performance relationship between binder types and aluminum-based lithium adsorbent.pdf
Published 2025“…It is noted that the structures of PVDF-LDH and PVC-LDH changed during temperature changes, resulting in decreased adsorption and desorption performance. …”
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5926
Data Sheet 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf
Published 2025“…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …”
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5927
Table 1_Therapeutic potential and mechanistic insights of silibinin targeting cancer-associated fibroblasts in colorectal cancer.xlsx
Published 2025“…Consistently, in vitro experiments demonstrated that SB significantly decreased both protein and mRNA levels of α-SMA and POSTN in fibroblasts (colonic myofibroblast CCD-18Co cell lines.) co-cultured with CRC cell lines (human colorectal adenocarcinoma SW480 and RKO cell lines). …”
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5928
Supplementary file 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf
Published 2025“…In the sarcopenia group, both GPRC5D-AS1 and SLC7A11 expression levels decreased significantly, along with SLC7A11 protein translation. …”
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5929
DataSheet_1_RETRACTED: Macrophages depletion alleviates lung injury by modulating AKT3/GXP4 following ventilator associated pneumonia.docx
Published 2024“…Depletion of macrophages protected against lung epithelial cells and significantly decreased MMP9, MMP19, FTH, and FTL expression levels and increased GPX4 expression levels, while partially reversing the changes in macrophage. …”
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5930
Table 1_Spontaneous neural activity alterations in medication-naïve primary blepharospasm: a resting-state functional magnetic resonance imaging study.docx
Published 2025“…</p>Results<p>Compared to healthy controls, medication-naïve patients with BSP exhibited significantly increased ALFF in the bilateral putamen and left premotor cortex and decreased ALFF in the bilateral thalamus (p < 0.05, threshold-free cluster enhancement with family-wise error correction for multiple comparisons). …”
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5931
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5932
Table 1_GLP1 receptor agonists and SGLT2 inhibitors for the prevention or delay of type 2 diabetes mellitus onset: a systematic review and meta-analysis.docx
Published 2025“…Finally, no significant change in fasting insulin levels was noticed with an overall SMD of -1.74 (95% CI: [-6.84, 3.37]), which was also not statistically significant (p-value: 0.55). …”
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5933
Presentation 1_Transcriptome signature in the blood of neuromyelitis optica spectrum disorder under steroid tapering.pptx
Published 2025“…Background<p>The advent of biologics has significantly transformed treatment strategies for neuromyelitis optica spectrum disorder (NMOSD). …”
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5934
Supplementary Material for: Pre- and post-operative Exercise and Nutrition Therapy in Patients with Esophageal Cancer Undergoing Esophagectomy: A Prospective Interventional Study
Published 2025“…Introduction: This study aimed to evaluate safety and feasibility of perioperative exercise and nutrition therapy, and to explore changes in skeletal muscle mass (SMM) in patients with esophageal cancer. …”
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5935
DataSheet1_Effects of Abelmoschus manihot (L.) and its combination with irbesartan in the treatment of diabetic nephropathy via the gut–kidney axis.PDF
Published 2024“…</p>Results<p>After treatment with HKC, EB, and their combination for 4 weeks, the urinary albumin-to-creatinine ratios decreased significantly in the db/db mice with DN. …”
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5936
Table 1_Characteristics of the vaginal microbiota and vaginal metabolites in women with cervical dysplasia.docx
Published 2024“…Correlation analysis revealed positive associations between CC group-decreased Lactobacillus abundance and CC group-decreased metabolites. …”
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5937
Table 1_Effect of a mindfulness-based cognitive behavior therapy intervention on occupational burnout among school teachers.docx
Published 2025“…</p>Results<p>The mean level of EE decreased during the post-test for both treatment (mean change -0.93, 95% CI: -2.56 to 0.70) and control (-1.71, 95% CI: -3.24 to -0.18) arms. …”
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5938
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5939
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5940
Table 1_Metabolome and transcriptome analysis reveal the pigments biosynthesis pathways in different color fruit peels of Clausena lansium L. Skeels.docx
Published 2025“…Despite the significant increase of FLS expression in PP, the contents of kaempferol, quercetin, and myricetin significantly decreased, suggesting that the increase of FLS expression did not lead to an increase in flavonol biosynthesis.…”