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changes decrease » larger decrease (Expand Search), change increases (Expand Search)
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significant changes » significant challenge (Expand Search)
changes decrease » larger decrease (Expand Search), change increases (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
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6021
Supplementary file 6_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx
Published 2025“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”
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6022
Supplementary file 2_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg
Published 2025“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”
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6023
Image_1_ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1.jpg
Published 2025“…This reduction correlated with changes in the expression of autophagic activity markers, suggesting decreased basal levels of autophagy in primary and metastatic melanomas. …”
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6024
Image_1_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg
Published 2024“…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …”
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6025
Supplementary file 5_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.docx
Published 2025“…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …”
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6026
Table 1_Co-frequency or contrary? The effects of Qiwei Baizhu Powder and its bioactive compounds on mucosa-associated microbiota of mice with antibiotic-associated diarrhea.docx
Published 2024“…The results showed that QWBZP-TG significantly altered the diversity, structure, and abundance of MAM in the AAD mice. …”
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6027
Image 1_Study on the ecosystem service flow based on the relationship of between supply and demand in Yangtze River Economic Belt.jpeg
Published 2024“…From 2015 to 2020, the number of areas with balanced supply and demand of ecosystem services in the Yangtze River Economic Belt decreases and the number of areas with unbalanced supply and demand increases, which is related to the changes in the level of economic development and land use patterns. 3). …”
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6028
<b>Increasing ECM tree dominance enhances </b><b>soil </b><b>lignin </b><b>phenols </b><b>but suppresses microbial necromass contribution to soil organic carbon in a subtropical </...
Published 2025“…Our results indicated that ECM% did not affect SOC content but significantly altered SOC composition. Specifically, a higher ECM% promoted accumulation of plant-derived C and reduced microbial-derived C. …”
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6029
Table 2_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a...
Published 2025“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”
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6030
DataSheet1_Diphenyl diselenide protects against diabetic kidney disease through modulating gut microbiota dysbiosis in streptozotocin-induced diabetic rats.docx
Published 2024“…</p>Results<p>The results showed DPDS and metformin improved the DKD in STZ rats, as evidenced by decreased blood glucose, BUN, urine volume, urine microalbumin, urinary β2 microglobulin, and improvement of renal pathological morphology. …”
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6031
Table 1_Effects of a community pharmacy-based structured medication review on drug-related problems in all-comers with polypharmacy: a randomized, controlled, double-blind, paralle...
Published 2025“…Therapy adherence- and health literacy-related DRPs decreased significantly by ~60% and ~64%, respectively. …”
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6032
Supplementary Material for: Focus on the Blind Spot of Stone Disease: Analysis of Lower Urinary Tract Stone Interventions from 2006 to 2020 using German nationwide inpatient data.
Published 2024“…Methods We analyzed data from the nationwide German hospital billing database from 2006 to 2020. The significance of changes over time was evaluated via linear regression analysis. …”
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6033
<i>map3k1</i> inhibition causes <i>ovo+</i> eye progenitors to undergo premature terminal differentiation.
Published 2025“…The number of undifferentiated <i>ovo</i><sup>+</sup> eye progenitors did not change significantly in <i>map3k1(RNAi)</i> worms at 0, 2, 5, and 8dpa. …”
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6034
DATA ALL PARTICIPANTS.xlsx
Published 2024“…The middle-aged adults had the smallest and the younger adults had the largest area under the curve. Across all ages, males completed fewer swallows, displayed greater average volumes per swallow, required significantly less time, and exhibited significantly less area under the curve when compared to females. …”
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6035
Effects of frequency difference, tactile conditions, and replicability.
Published 2025“…Participants’ perception of segregation was significantly lower in Tact B compared to Tact A. <b>C:</b> The change in proportion segregated compared to reference condition Tact Off.…”
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6036
Data Sheet 2_Assessing the impact of moxibustion on colonic mucosal integrity and gut microbiota in a rat model of cerebral ischemic stroke: insights from the “brain-gut axis” theo...
Published 2025“…The model group demonstrated decreased expression of Occludin and ZO-1 in colonic tissues (p < 0.01) and changes in gut microbiota structure. …”
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6037
Data Sheet 1_Assessing the impact of moxibustion on colonic mucosal integrity and gut microbiota in a rat model of cerebral ischemic stroke: insights from the “brain-gut axis” theo...
Published 2025“…The model group demonstrated decreased expression of Occludin and ZO-1 in colonic tissues (p < 0.01) and changes in gut microbiota structure. …”
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6038
Data Sheet 2_Long-term aerobic exercise improves learning memory capacity and effects on oxidative stress levels and Keap1/Nrf2/GPX4 pathway in the hippocampus of APP/PS1 mice.docx
Published 2024“…The level of ROS in the hippocampal region was significantly reduced by aerobic exercise (p < 0.05), with decreased Keap1 protein expression of and increased Nrf2, HO-1, GPX4 protein expression (p < 0.05).…”
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6039
Data Sheet 1_Long-term aerobic exercise improves learning memory capacity and effects on oxidative stress levels and Keap1/Nrf2/GPX4 pathway in the hippocampus of APP/PS1 mice.zip
Published 2024“…The level of ROS in the hippocampal region was significantly reduced by aerobic exercise (p < 0.05), with decreased Keap1 protein expression of and increased Nrf2, HO-1, GPX4 protein expression (p < 0.05).…”
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6040
Table 1_Microbial diversity and community assembly in heavy metal-contaminated soils: insights from selenium-impacted mining areas.xlsx
Published 2025“…Heavy metal pollution significantly impacts soil microbial communities due to its persistence and long-term residual effects. …”