يعرض 6,221 - 6,240 نتائج من 6,756 نتيجة بحث عن '(( significant changes decrease ) OR ( significant ((changes decrease) OR (largest decrease)) ))', وقت الاستعلام: 0.47s تنقيح النتائج
  1. 6221

    Table 5_Probiotic Bacillus pumilus LV149 enhances gut repair, modulates microbiota, and alters transcriptome in DSS-induced colitis mice.xlsx حسب Xinyu Sun (426009)

    منشور في 2025
    "…Notably, only the LV149-H significantly decreased the expression of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6, while both doses increased the expression of the anti-inflammatory cytokine IL-10 in a dose-dependent in colonic tissue. …"
  2. 6222

    Table 1_To MRAs treatment or not? evidence from a meta-analysis of randomized controlled trials of different MRAs on cardiovascular health in heart failure.docx حسب Jinyu He (19774641)

    منشور في 2025
    "…Moreover, MRAs significantly improved LVEF (WMD = 1.384, 95% CI: 0.208–2.559, p = 0.021; I<sup>2</sup> = 59.9%). …"
  3. 6223

    Table 2_Probiotic Bacillus pumilus LV149 enhances gut repair, modulates microbiota, and alters transcriptome in DSS-induced colitis mice.xlsx حسب Xinyu Sun (426009)

    منشور في 2025
    "…Notably, only the LV149-H significantly decreased the expression of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6, while both doses increased the expression of the anti-inflammatory cytokine IL-10 in a dose-dependent in colonic tissue. …"
  4. 6224

    Table 3_Probiotic Bacillus pumilus LV149 enhances gut repair, modulates microbiota, and alters transcriptome in DSS-induced colitis mice.xlsx حسب Xinyu Sun (426009)

    منشور في 2025
    "…Notably, only the LV149-H significantly decreased the expression of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6, while both doses increased the expression of the anti-inflammatory cytokine IL-10 in a dose-dependent in colonic tissue. …"
  5. 6225

    Table 1_Comparative proteomic analysis of the telogen-to-anagen transition in cashmere goat secondary hair follicles.pdf حسب Xiaoyu Han (550622)

    منشور في 2025
    "…This study explores the phenotypic changes and differential protein expression profiles involved in the telogen-to-anagen transition of SHFs. …"
  6. 6226

    Table 3_To MRAs treatment or not? evidence from a meta-analysis of randomized controlled trials of different MRAs on cardiovascular health in heart failure.docx حسب Jinyu He (19774641)

    منشور في 2025
    "…Moreover, MRAs significantly improved LVEF (WMD = 1.384, 95% CI: 0.208–2.559, p = 0.021; I<sup>2</sup> = 59.9%). …"
  7. 6227

    Image 2_Probiotic Bacillus pumilus LV149 enhances gut repair, modulates microbiota, and alters transcriptome in DSS-induced colitis mice.tif حسب Xinyu Sun (426009)

    منشور في 2025
    "…Notably, only the LV149-H significantly decreased the expression of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6, while both doses increased the expression of the anti-inflammatory cytokine IL-10 in a dose-dependent in colonic tissue. …"
  8. 6228

    Table 1_Probiotic Bacillus pumilus LV149 enhances gut repair, modulates microbiota, and alters transcriptome in DSS-induced colitis mice.xlsx حسب Xinyu Sun (426009)

    منشور في 2025
    "…Notably, only the LV149-H significantly decreased the expression of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6, while both doses increased the expression of the anti-inflammatory cytokine IL-10 in a dose-dependent in colonic tissue. …"
  9. 6229

    Table 1_Weizmannia coagulans BC99 regulates oxidative stress and serum metabolic pathways to improve allergic rhinitis: a randomized, double-blind, placebo-controlled trial.docx حسب Xuan Li (137217)

    منشور في 2025
    "…Furthermore, BC99 supplementation significantly decreased serum IgA, complement C3, EOS, and MDA levels (p < 0.05) while enhancing antioxidant capacity (increased GSH, stabilized SOD). …"
  10. 6230

    Image 4_Probiotic Bacillus pumilus LV149 enhances gut repair, modulates microbiota, and alters transcriptome in DSS-induced colitis mice.tif حسب Xinyu Sun (426009)

    منشور في 2025
    "…Notably, only the LV149-H significantly decreased the expression of pro-inflammatory cytokines TNF-α, IL-1β, and IL-6, while both doses increased the expression of the anti-inflammatory cytokine IL-10 in a dose-dependent in colonic tissue. …"
  11. 6231

    Data Sheet 1_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip حسب Hai-Qing Tan (22173514)

    منشور في 2025
    "…Temporal trends were evaluated via the estimated annual percentage change (EAPC) and average annual percentage change (AAPC). …"
  12. 6232

    Data Sheet 3_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip حسب Hai-Qing Tan (22173514)

    منشور في 2025
    "…Temporal trends were evaluated via the estimated annual percentage change (EAPC) and average annual percentage change (AAPC). …"
  13. 6233

    Supplementary file 1_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.docx حسب Hai-Qing Tan (22173514)

    منشور في 2025
    "…Temporal trends were evaluated via the estimated annual percentage change (EAPC) and average annual percentage change (AAPC). …"
  14. 6234

    Data Sheet 4_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip حسب Hai-Qing Tan (22173514)

    منشور في 2025
    "…Temporal trends were evaluated via the estimated annual percentage change (EAPC) and average annual percentage change (AAPC). …"
  15. 6235

    Image2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... حسب Huijing Ren (19986303)

    منشور في 2024
    "…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …"
  16. 6236

    DataSheet1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer... حسب Huijing Ren (19986303)

    منشور في 2024
    "…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …"
  17. 6237

    Image1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... حسب Huijing Ren (19986303)

    منشور في 2024
    "…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. Further in vivo and in vitro experiments confirmed that varying doses of CPGB formula effectively ameliorated STZ-induced cognitive deficits, as shown by NOR, MWM, and EMP tests, as well as pathological changes in hippocampal tissues and a 3-dimensional brain neurovascular unit (3D-NVU) model, including decreased deposition of Aβ protein and formation of plaques. …"
  18. 6238

    Table 1_Xinfeng Capsule inhibits oxidative stress via regulating the PPARγ/ Hmgcs2 signaling pathway in lung tissue of adjuvant arthritis rats.docx حسب Ping-Heng Zhang (21785162)

    منشور في 2025
    "…Furthermore, XFC-containing serum suppressed TGF-β1–induced proliferation of lung fibroblasts, promoted PPARγ expression, and significantly decreased the levels of interleukin-6, tumor necrosis factor-α, reactive oxygen species, nicotinamide adenine dinucleotide phosphate oxidase 4, HMGCS2, collagen type I α 1, collagen type III α 1, and α-smooth muscle actin (P < 0.01). …"
  19. 6239

    DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx حسب Gerui Li (15648920)

    منشور في 2024
    "…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …"
  20. 6240

    Data Sheet 1_Suppressed intestinal secondary bile acids in moxifloxacin-induced hyperglycemia: studies in normal and diabetic GK rats.docx حسب Yewen Sun (8334138)

    منشور في 2025
    "…Gut microbiota associated with SBAs metabolism were significantly reduced, leading to decreased intestinal deoxycholic acid (DCA) and lithocholic acid (LCA). …"