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significant changes » significant challenge (Expand Search)
changes decrease » larger decrease (Expand Search), largest decrease (Expand Search), change increases (Expand Search)
small decrease » small increased (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), mean decrease (Expand Search)
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4841
DataSheet1_Effects of pharmacogenomics-guided treatment on medication adherence and the antidepressant switching rate in major depressive disorder.docx
Published 2024“…The difference was also significant after 6 months (38.06% in the PGxT group vs. 24.84% in the TAU group; p < 0.001). …”
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4842
Image_1_Widely targeted metabolomics and SPME-GC-MS analysis revealed the quality characteristics of non-volatile/volatile compounds in Zheng’an Bai tea.tif
Published 2024“…However, these changing characteristics have not yet been revealed.…”
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4843
DataSheet1_Kinetics of endothelin-1 and effect selective ETA antagonism on ETB activation: a mathematical modeling analysis.docx
Published 2024“…By varying both drug ET<sub>A</sub> selectivity (K<sub>ib</sub>/K<sub>ia</sub>) and concentration over a wide range, simulations predicted that while selective ET<sub>A</sub> antagonist (selectivity >1) always decreased [ET1-ET<sub>A</sub>], the change in [ET1-ET<sub>B</sub>] was more complex. …”
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4844
Table_4_Widely targeted metabolomics and SPME-GC-MS analysis revealed the quality characteristics of non-volatile/volatile compounds in Zheng’an Bai tea.xls
Published 2024“…However, these changing characteristics have not yet been revealed.…”
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4845
Data_Sheet_1_Effects of a 30-min rest with a nap chair on task performance, sleepiness, and neurophysiological measures in men with suspected brain fatigue: a randomized controlled...
Published 2024“…The Karolinska Sleepiness score significantly decreased after the nap-chair rest, and the between-treatment difference in the decrease was highly significant (P = 0.0004). …”
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4846
Table 1_Modulation of the gut-bone axis: Lacticaseibacillus paracasei LC86 improves bone health via anti-inflammatory metabolic pathways in zebrafish models of osteoporosis and car...
Published 2025“…Gut microbiota analysis demonstrated an increase in beneficial bacteria and a decrease in pathogenic genera.</p>Conclusions<p>LC86 significantly improved bone health, cartilage structure, and gut microbiota composition in a Dexamethasone-induced zebrafish model, supporting its potential as a therapeutic strategy for osteoporosis and cartilage injury via modulation of the gut-bone axis.…”
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4847
Table 1_Tregs levels and phenotype modifications during Amyotrophic Lateral Sclerosis course.docx
Published 2025“…</p>Results<p>Our study showed that Treg levels did not change significantly on average during the observation period in our ALS cohort. …”
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4848
Frequency of short–term outcomes of IVH.
Published 2025“…<div><p>Background</p><p>Intraventricular hemorrhage (IVH) stands as the predominant cause of brain injury with the incidence increasing with the decrease in birth weight and gestational age. In developed countries, a reduction in IVH incidence by implementing small baby neuroprotective protocols has been reported. …”
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4849
Burden trends and risk factors for prostate cancer from 1990 to 2021: a systematic analysis of the Global Burden of Disease Study 2021
Published 2025“…</p> <p>Average annual percent change for age-standardized rate trend was calculated by Joinpoint. …”
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4850
Data Sheet 1_Case series: Effects of a ketogenic diet on cardiometabolic health in seven outpatients with bipolar disorder.pdf
Published 2025“…While some studies have shown no significant change in cholesterol levels, and some have shown improvements, still others have highlighted the potential of KDs to induce or exacerbate hyperlipidemia.…”
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4851
Untargeted Urinary Proteomics Uncovers Nephroprotective and Systemic Adaptations after Obesity Surgery-Induced Weight Loss
Published 2025“…Untargeted high-resolution LC-MS with label-free quantification was used to assess urinary proteome changes. Among the 2347 identified proteins, 1016 depicted a significantly different abundance postsurgery (<i>p</i> < 0.05). …”
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4852
Hemodynamic mechanisms underlying orthostatic hypotension in stroke survivors: a cross-sectional study
Published 2025“…These individuals demonstrated significantly greater orthostatic cardiac index increases (F<sub>(5,105)</sub> = 2.75, <i>p</i> = 0.023, partial η<sup>2</sup> = 0.126) and more pronounced orthostatic total peripheral resistance index decreases (F<sub>(5,105)</sub> = 4.19, <i>p</i> = 0.002, partial η<sup>2</sup> = 0.166) than those without orthostatic hypotension.…”
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4853
Supplementary Material for: Preliminary efficacy, tolerability, and safety analysis of Darolutamide for metastatic castration‑resistant prostate cancer: a single-center, open-label...
Published 2024“…The median time to PSA50 in the Darolutamide group was 1.5 months (95%CI 0.2619- 0.9545), significantly lower than that in the placebo group (3.0 months [95%CI 1.048- 3.818], p= 0.0259); The median time to PSA90 in the experimental group was 4 months (95%CI 0.3094- 1.437), 2 months shorter than that in the placebo group (6.0 months [95%CI 0.6961- 3.232]).With the median follow-up of 6 months, , the median decrease in serum PSA was -81.8% (range -60.4 to -99.9%) in the Darolutamide group and -69.4% (range -50.3 to -89.6%) in the placebo group. …”
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4854
S1_Figure.pdf
Published 2025“…We observed no age-associated changes in coupling efficiency (ADP:O) of mitochondrial reticulum preparations, but respiratory control (RCR) was decreased in older mice. …”
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4855
Data Sheet 1_Epidemiology and factors associated with the perioperative course of patients undergoing hip fracture during the initial phase of the state of emergency declared in 20...
Published 2025“…A statistically significant decrease in leukocyte and hemoglobin levels was observed after surgery. …”
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4856
Data Sheet 2_Epidemiology and factors associated with the perioperative course of patients undergoing hip fracture during the initial phase of the state of emergency declared in 20...
Published 2025“…A statistically significant decrease in leukocyte and hemoglobin levels was observed after surgery. …”
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4857
Data Sheet 3_Epidemiology and factors associated with the perioperative course of patients undergoing hip fracture during the initial phase of the state of emergency declared in 20...
Published 2025“…A statistically significant decrease in leukocyte and hemoglobin levels was observed after surgery. …”
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4858
Supplementary Material for: Effects of wearing hearing aids on gait and cognition: A pilot study
Published 2025“…Although these results should be interpreted with caution due to the non-randomized controlled trial design and small sample size, the findings suggest that improving hearing acuity among older adults may enhance their overall health status.…”
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4859
多杀性巴氏杆菌流行过程中水平基因转移对其毒力与耐药的影响-附录.xlsx
Published 2024“…Consequently, the deletion of A0R64_02365, a unique HGT-sourced gene in the hypervirulent poultry-sourced PM DY120818, triggers significant transcriptional changes in a cluster of protease genes specific to this virulence phenotype. …”
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4860
Table 1_Impact of the Yangtze River on Sediment source-to-sink processes in estuarine bays: a study of the Oujiang River Estuary, SE China.docx
Published 2025“…In conclusion, our study underscores the significant influence of sediments from the Yangtze River on the surface sediments in small mountain rivers and offshore regions near the Zhejiang coastline.…”