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significant changes » significant challenge (Expand Search)
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3941
Table 1_Ranges, temporal trend, and determinants of novel obesity indices in middle-aged and older Chinese population: insights from a nationally representative and longitudinal st...
Published 2025“…Over the five-year period, WHtR, CVAI, and LAP increased significantly (β = 0.00489, β = 4.51607, β = 6.37441; all p < 0.001), while ABSI decreased (β = −0.00048, p < 0.001). …”
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3942
Table 4_Ranges, temporal trend, and determinants of novel obesity indices in middle-aged and older Chinese population: insights from a nationally representative and longitudinal st...
Published 2025“…Over the five-year period, WHtR, CVAI, and LAP increased significantly (β = 0.00489, β = 4.51607, β = 6.37441; all p < 0.001), while ABSI decreased (β = −0.00048, p < 0.001). …”
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3943
Table 5_Ranges, temporal trend, and determinants of novel obesity indices in middle-aged and older Chinese population: insights from a nationally representative and longitudinal st...
Published 2025“…Over the five-year period, WHtR, CVAI, and LAP increased significantly (β = 0.00489, β = 4.51607, β = 6.37441; all p < 0.001), while ABSI decreased (β = −0.00048, p < 0.001). …”
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3944
Table 2_Ranges, temporal trend, and determinants of novel obesity indices in middle-aged and older Chinese population: insights from a nationally representative and longitudinal st...
Published 2025“…Over the five-year period, WHtR, CVAI, and LAP increased significantly (β = 0.00489, β = 4.51607, β = 6.37441; all p < 0.001), while ABSI decreased (β = −0.00048, p < 0.001). …”
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3945
Data Sheet 1_Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040.docx
Published 2025“…The By 2040, the BAPC model projects significant declines in global ASMR and age-standardized DALYs rates, while ASIR is expected to decrease in females but increase in males and across both sexes.…”
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3946
Table 3_Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040.xlsx
Published 2025“…The By 2040, the BAPC model projects significant declines in global ASMR and age-standardized DALYs rates, while ASIR is expected to decrease in females but increase in males and across both sexes.…”
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3947
Table 2_Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040.docx
Published 2025“…The By 2040, the BAPC model projects significant declines in global ASMR and age-standardized DALYs rates, while ASIR is expected to decrease in females but increase in males and across both sexes.…”
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3948
Table 1_Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040.docx
Published 2025“…The By 2040, the BAPC model projects significant declines in global ASMR and age-standardized DALYs rates, while ASIR is expected to decrease in females but increase in males and across both sexes.…”
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3949
Assessing sandbar morphology in the Nakdong River Estuary using SPOT series satellite imagery
Published 2025“…Doyo Sandbar’s southern shoreline is retreating at 14.69 m/year, with a gradual decrease in speed. Significant topographical changes indicate that the interlinked barrier islands are undergoing deposition and erosion, altering the shoreline.…”
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3950
Supplementary Material for: Analysis of retinal and choroidal microvasculature in systemic sclerosis using optical coherence tomography angiography: A systematic review and meta-an...
Published 2024“…Meta-analysis findings revealed a significant decrease in vessel densities in both the superficial and deep capillary plexuses (SCP and DCP) among SSc patients compared to controls. …”
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3951
Supplemental Tables S1-S5
Published 2025“…LFD and HFD mice lost an average of 11% and 27% of their body weight, respectively. LFD mice had a 33% decrease in CCL20 in lung tissue and a 55% decrease in neutrophils in BALF. …”
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3952
Supplemental Figs. S1-S7
Published 2025“…LFD and HFD mice lost an average of 11% and 27% of their body weight, respectively. LFD mice had a 33% decrease in CCL20 in lung tissue and a 55% decrease in neutrophils in BALF. …”
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3953
Table 1_Apparent reduction in heart rate during oviposition revealed by non-invasive heart rate monitoring of gravid loggerhead turtles.xls
Published 2025“…<p>Reproductive processes place significant physiological demands on animals, often accompanied by hormonal and neural changes. …”
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3954
Data Sheet 1_Predictive value of percutaneous peripheral arterial compliance T in left ventricular diastolic function with coronary artery disease.pdf
Published 2024“…</p>Conclusions<p>When coronary artery stenosis exceeds 50%, there is a decrease in peripheral artery compliance, showing a positive correlation with changes in left ventricular diastolic function. …”
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3955
Data Sheet 2_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio...
Published 2025“…</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”
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3956
Data Sheet 1_Modulation of gut microbiota by Gardeniae Fructus oil exerts TLR4/NF-κB/NLRP3 pathway-mediated antidepressant effects based on transcriptomics and fecal transplantatio...
Published 2025“…</p>Results<p>Compared with the CON group, mice in the CUMS group showed significant depressive-like behavior, pathological damage to the hippocampus and colon tissues, significant decrease in levels of 5-HT, DA, and BDNF in the hippocampus, significant increase in levels of IL-1β, IL-6, TNF-α, DAO, and LPS in serum, significant decrease in colonic tight junction protein expression, and significant increase in protein expression of TLR4, p-NF-κB, NLRP3, ASC, and IL-1β in the hippocampus (P < 0.01); Compared with the CUMS group, the FMT group could effectively improve the above situation (P < 0.05, P < 0.01), whose therapeutic effect was second only to the OGF group (P < 0.01), while ABX + OGF group did not show obvious therapeutic effect.…”
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3957
Table 1_Real world efficacy and safety of the advanced hybrid closed-loop system MiniMed 780G (SmartGuard) in children under 7 years of age.docx
Published 2025“…In Group 2, there was a significant increase in the TIR (7%; p = 0,000) and a significant decrease in the TAR (7%; p = 0,000 for TAR1 and 6.5%; p = 0,001 for TAR2). …”
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3958
Supplementary file 2_Impact of NF-κB and reactive oxygen species on intracellular BAFF/APRIL expression in ANCA-associated vasculitis: focusing on the effect of resveratrol.docx
Published 2025“…Patients with AAV showed a significant decrease in APRIL expression without significant changes in BAFF expression in CD14+ cells treated with tempol; whereas there was a significant decrease in BAFF and APRIL expression in CD14+ cells treated with SN50. …”
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3959
Supplementary file 1_Impact of NF-κB and reactive oxygen species on intracellular BAFF/APRIL expression in ANCA-associated vasculitis: focusing on the effect of resveratrol.pptx
Published 2025“…Patients with AAV showed a significant decrease in APRIL expression without significant changes in BAFF expression in CD14+ cells treated with tempol; whereas there was a significant decrease in BAFF and APRIL expression in CD14+ cells treated with SN50. …”
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3960
Data Sheet 1_Perturbations in gut microbiota composition in patients with autoimmune neurological diseases: a systematic review and meta-analysis.pdf
Published 2025“…Regarding α-diversity, except for Chao1, which showed a consistent small decrease (SMD = −0.26, 95% CI = −0.45 to −0.07, p < 0.01), other indices demonstrated no significant changes. …”