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significant changes » significant challenge (توسيع البحث)
changes decrease » larger decrease (توسيع البحث), largest decrease (توسيع البحث), change increases (توسيع البحث)
greater decrease » greatest decrease (توسيع البحث), greater increase (توسيع البحث), greater disease (توسيع البحث)
small decrease » small increased (توسيع البحث)
significant changes » significant challenge (توسيع البحث)
changes decrease » larger decrease (توسيع البحث), largest decrease (توسيع البحث), change increases (توسيع البحث)
greater decrease » greatest decrease (توسيع البحث), greater increase (توسيع البحث), greater disease (توسيع البحث)
small decrease » small increased (توسيع البحث)
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7001
Table 1_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair...
منشور في 2025"…<p>In both humans and mice, obesity is often associated with peripheral and central inflammation, which can lead to diabetes, dysregulation of the stress response, changes in affective behavior, and memory impairment. …"
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7002
Data Sheet 1_Targeting the leptin receptor promotes MDA-MB-231 cells’ metabolic reprogramming and malignancy: the role of extracellular vesicles derived from obese adipose tissue.d...
منشور في 2025"…Additionally, OB EVs caused metabolic changes, including reduced lactate levels and decreased pyruvate kinase (PK) activity, while increasing glucose-6-phosphate dehydrogenase (G6PDH) activity, suggesting metabolic reprogramming that supports tumor cell survival and proliferation. …"
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7003
Data Sheet 1_Dynamic stability of gut microbiota in elite volleyball athletes: microbial adaptations during training, competition and recovery.pdf
منشور في 2025"…The Firmicutes/Bacteroidetes ratio fluctuated in response to training intensity and competition 6:1 during T0 and T1, decreasing to 3:1 during T2 and returning to 5:1 during T3. …"
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7004
Image 2_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer...
منشور في 2025"…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …"
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7005
Table 3_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx
منشور في 2025"…Cluster analysis revealed significant changes in gene expression patterns: DEGs associated with mitochondrial function [including oxidative phosphorylation and citrate cycle (TCA cycle) pathways] were down-regulated, while most DEGs involved in glutathione metabolism were up-regulated. …"
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7006
Image 1_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer...
منشور في 2025"…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …"
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7007
Yeast strains used in this study.
منشور في 2025"…While H2A.Z has often been implicated in transcription regulation, <i>htz1</i>Δ mutants exhibit minimal changes in gene expression compared to wild-type. …"
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7008
Data Sheet 1_Liuweizhiji Gegen-Sangshen beverage protects against alcoholic liver disease in mice through the gut microbiota mediated SCFAs/GPR43/GLP-1 pathway.docx
منشور في 2024"…LGS significantly improved liver steatosis, enhanced activities of alcohol metabolizing enzymes (ALDH and ADH), and reduced the CYP2E1 activity. …"
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7009
Image 1_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair...
منشور في 2025"…<p>In both humans and mice, obesity is often associated with peripheral and central inflammation, which can lead to diabetes, dysregulation of the stress response, changes in affective behavior, and memory impairment. …"
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7010
Table 2_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.docx
منشور في 2025"…Cluster analysis revealed significant changes in gene expression patterns: DEGs associated with mitochondrial function [including oxidative phosphorylation and citrate cycle (TCA cycle) pathways] were down-regulated, while most DEGs involved in glutathione metabolism were up-regulated. …"
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7011
Image 3_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer...
منشور في 2025"…</p>Results<p>At this concentration, BHB significantly and concentration-dependently decreased the following: 1) inflammatory cytokine expression (IL-6, TNF-α, and IL-1β), 2) inflammatory morphological changes, and 3) activation of p-ERK and p-p38MAPK, which are key pathways involved in microglial inflammation. …"
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7012
Supplementary file 1_Effects of different urban vegetation cover and green space types on soil greenhouse gas emissions and carbon sequestration.docx
منشور في 2025"…The annual increase of SOC in residential and streets was notably lower than that in parks green spaces, by 9.59% and 15.20%, respectively, indicating significant differences. This suggests that soil carbon sequestration capacity is highly responsive to changes in vegetation coverage and green space types, with WSOC, NH<sub>4</sub><sup>+</sup>-N, and pH identified as the primary factors influencing the greenhouse gas flux in the three soils. …"
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7013
CLAD_sequence_files
منشور في 2025"…Association with CLAD severity was driven by changes in phosphoethanolamine and phosphocholine lipids that increased and decreased, respectively, and metabolites from the bacterial pathogen <i>Pseudomonas aeruginosa</i>. …"
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7014
Table 7_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx
منشور في 2025"…Cluster analysis revealed significant changes in gene expression patterns: DEGs associated with mitochondrial function [including oxidative phosphorylation and citrate cycle (TCA cycle) pathways] were down-regulated, while most DEGs involved in glutathione metabolism were up-regulated. …"
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7015
Datasheet1_Endovascular treatment of aortic coarctation using covered balloon-expandable stents—a systematic review and meta-analysis.pdf
منشور في 2024"…The estimated pooled procedural success rate was 100% [95% confidence interval (CI): 98%–100%, I2 = 0, P = 0.78]. Significant decreases in trans-coarctation PGs and SBP were observed. …"
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7016
Table 1_Global, regional, and national disease burden and economic costs of cervical cancer (1991–2021): a multidimensional data synthesis analysis.docx
منشور في 2025"…Despite the 2018 elimination initiative, overall incidence and mortality trends showed minimal change. Age-specific incidence notably decreased in individuals over 70, with slower mortality declines in higher age groups. …"
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7017
Table 4_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair...
منشور في 2025"…<p>In both humans and mice, obesity is often associated with peripheral and central inflammation, which can lead to diabetes, dysregulation of the stress response, changes in affective behavior, and memory impairment. …"
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7018
Data Sheet 1_Evolving trends and burden of idiopathic epilepsy among children (0–14 years), 1990–2021: a systematic analysis for the Global Burden of Disease study 2021.zip
منشور في 2025"…Joinpoint regression analyses assessed changes over time, calculating average annual percentage change (AAPC) statistics. …"
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7019
Supplementary file 1_Global burden of HIV, syphilis, and HBV infection among women of childbearing age and children under five: based on the Global Burden of Diseases Study 2021.do...
منشور في 2025"…Both the ASPR of HBV infection among WCBA and the ASIR among children under five declined significantly from 1990 to 2021, with average annual percentage changes of −1.25% and −4.14%, respectively. …"
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7020
Data Sheet 1_Artificial clicks (Porpoise ALert) affect acoustic monitoring of harbour porpoises and their echolocation behaviour.pdf
منشور في 2025"…The results revealed a reduction in the number of porpoise clicks during PAL operation, and changes in echolocation patterns characterised by increased minimum Inter-click-intervals (ICI), suggesting a shift from foraging or communication to orientation activity, and decreased maximum ICI, indicating enhanced long-range orientation. …"