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18061
Table 1_Regulation of DNA methylation in lesional tissue of children with atopic dermatitis.docx
Published 2025“…</p>Results<p>The mRNA expression levels of DNMT3A genes were significantly increased, while the mRNA expression levels of DNMT3B, TET1, and TET2 genes were statistically significantly reduced in the lesional tissue of patients compared to the control group. …”
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18062
High-throughput single-cell analysis reveals Omp38-specific monoclonal antibodies that protect against <i>Acinetobacter baumannii</i> infection
Published 2024“…Intravenous administration of the Omp38-specific mAbs significantly improved the survival rate and reduced the bacterial load in a mouse model of lethal <i>A. baumannii</i> infection. …”
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18063
Table 1_Immunomodulatory peptide–drug conjugate MEL-dKLA suppresses progression of prostate cancer by eliminating M2-like tumor-associated macrophages.docx
Published 2025“…In vivo, MEL-dKLA treatment significantly reduced tumor growth, decreased the number of CD163<sup>+</sup> M2 macrophages, and increased CD8<sup>+</sup> T cell infiltration in tumor tissues. …”
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18064
Table 2_Immunomodulatory peptide–drug conjugate MEL-dKLA suppresses progression of prostate cancer by eliminating M2-like tumor-associated macrophages.docx
Published 2025“…In vivo, MEL-dKLA treatment significantly reduced tumor growth, decreased the number of CD163<sup>+</sup> M2 macrophages, and increased CD8<sup>+</sup> T cell infiltration in tumor tissues. …”
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18065
Further characterization of N19 and calcium dependence.
Published 2025“…<p>(<b>A</b>) N19 decreases MR1 presentation of Mtb when added at the same time as infection. 25µM N19 was added to BEAS-2Bs the same time as Mtb (MOI 8). …”
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18066
Table 1_Therapeutic effects of composite probiotics derived from fermented camel milk on metabolic dysregulation and intestinal barrier integrity in type 2 diabetes rats.docx
Published 2025“…The OGTT AUC decreased by 40.1% (p < 0.001), and HbA1c levels fell by 22.9% (p < 0.01). …”
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18067
Short-term antiretroviral therapy may not correct the dysregulations of plasma virome and cytokines induced by HIV-1 infection
Published 2025“…Notably, most dysregulated cytokines were not fully restored by ART, with extremely abnormal levels of IL-10, GM-CSF, VEGF, and eotaxin, and a significantly increased level of plasma I-FABP. …”
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18068
Data Sheet 1_Effects of different fermentation temperatures on microbiomes of cigar tobacco leaves.pdf
Published 2025“…</p>Results<p>The bacterial biomass increased initially and peaked at 8.4 × 10<sup>9</sup> copies/g at 35°C, then decreased as the temperature rose. The fungal biomass exhibited a downward trend with increasing temperature, reaching a maximum of 3.9 × 10<sup>6</sup> copies/g at 30°C. …”
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18069
Supplementary Material for: Protein inhibitor of activated STAT 2 (PIAS2) protects against podocyte injury in diabetic nephropathy via inhibiting JAK2/STAT3 pathway
Published 2025“…Overexpression of PIAS2 significantly reversed high glucose-induced human podocytes injury, evidenced by increased cell viability, reduced cell apoptosis, decreased expression of pro-apoptotic proteins Bax and cleaved-Caspase3, increased expression of the anti-apoptotic protein Bcl-2, and reduced secretion of pro-inflammatory cytokines IL-1β, IL-6, and TNF-α. …”
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18070
Table1_Carex parva and Carex scabrirostris adopt diverse response strategies to adapt to low-light conditions.docx
Published 2024“…Introduction<p>In recent years, the visible light intensity of lawns has significantly decreased due to obstructions caused by urban shading objects. …”
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18071
Table 1_Exploring the role of LOX family in glioma progression and immune modulation.docx
Published 2025“…Background<p>Glioma is a major cause of mortality among central nervous system tumors, with a generally poor prognosis. …”
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18072
Image 1_Exploring the role of LOX family in glioma progression and immune modulation.jpeg
Published 2025“…Background<p>Glioma is a major cause of mortality among central nervous system tumors, with a generally poor prognosis. …”
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18073
Molecular characterization of zinc metalloproteinase Nas-14 from Trichinella spiralis and its participation in intestinal invasion
Published 2025“…In addition, the direct incubation of rTsNas14 with claduin-1 showed that rTsNas14 could significantly degrade claudin-1. In vivo studies have demonstrated that inhibition of TsNas14 expression significantly impairs the infectivity of T. spiralis in mice, resulting in a decreased AW and muscle larval burden. …”
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18074
Supplementary Material for: Efficacy of Spray Cryotherapy on Airway Secretions in Canine Models of Chronic Bronchitis and Mechanism Insights
Published 2025“…Conclusion The SO2 inhalation protocol effectively establishes a CB model in dogs. SCT effectively treats CB by reducing mucin levels and may lower MUC5AC expression by decreasing acetylcholine and CHRM3.…”
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18075
Data Sheet 1_Inhibition of biofilm formation and preformed biofilm in Acinetobacter baumannii by resveratrol, chlorhexidine and benzalkonium: modulation of efflux pump activity.zip
Published 2024“…The combination of RV with CHX and BZK additively decreased minimal biofilm eradicating concentrations in A. baumannii strains.…”
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18076
Data Sheet 1_Pinostilbene inhibits lung epithelial-mesenchymal transition and delays pulmonary fibrosis by modulating the PI3K/Akt pathway.docx
Published 2025“…Cellular experiments using A549 and Beas2B cells showed that PIN significantly reduced TGF-β1-induced mesenchymal marker expression while increasing epithelial marker expression. …”
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18077
Table 1_Litter quality outweighs climate in driving grassland root decomposition.docx
Published 2025“…With respect to biotic factors, grazing (+7.51%) significantly increased decomposition, whereas vegetated soil (−27.84%), increased plant species richness (−4.99%), increased root litter richness (−5.93%), home-field decomposition (−4.34%), and soil biota exclusion (−10.40%) decreased it.…”
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18078
Table 1_Refrigerator ownership and the nutrition-health trade-off: evidence from Chinese households.docx
Published 2025“…The ratios of energy derives from fat and protein rose by 0.104 and 0.018 percentage points, respectively, while the carbohydrate energy ratio decreases by 0.12 percentage points, indicating a shift towards a higher energy-dense diet. …”
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18079
Supplementary file 1_Association between olfactory dysfunction and gustatory dysfunction: evidence from the National Health and Nutrition Examination Survey.docx
Published 2025“…Similarly, the questionnaire data revealed that OD significantly increased the odds of GD. However, hyposmia OD decreased the odds of hypogeusia GD using the tongue-tip taste measurement.…”
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18080
Table 1_Mangiferin mitigates neurological deficits and ferroptosis via NRF2/ARE pathway activation in cerebral ischemia-reperfusion rats.xlsx
Published 2025“…Ferroptosis in stroke rats was significantly inhibited by MGF. MGF significantly increased the expression of NRF2, FTL, SLC7A11 and GPX4. …”