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significant changes » significant challenge (Expand Search)
changes decrease » larger decrease (Expand Search), largest decrease (Expand Search), change increases (Expand Search)
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10981
Image 1_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”
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10982
Data Sheet 1_α-Mangostin prevents diabetic cardiomyopathy by inhibiting oxidative damage and lipotoxicity through the AKT–FOXO1–CD36 pathway.pdf
Published 2025“…Oxidative stress and lipid metabolism disorder-induced myocardial cell damage are part of the pathogenesis of DCM. In this study, we investigated the effects of alpha-mangostin (A-MG), a natural antioxidant extracted from mangosteen peel, on in vitro and in vivo DCM models.…”
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10983
Image 2_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”
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10984
Image 5_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”
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10985
P4HA3 deficiency increased sensitization to immune checkpoint inhibitors and P4HA3 could predict the clinical therapeutic effect of PD-1 inhibitor (Camrelizumab).
Published 2024“…P4HA3 and Ki-67 were decreased in the knockdown groups by siRNA compared to the NC group. …”
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10986
Image 3_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”
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10987
Image 4_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff
Published 2025“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”
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10988
A Proposal for Implementation of Multi-Factor Authentication (MFA) System for Enhanced Security By Stephen Mikah Makoshi
Published 2025“…<b>Reduced Reliance on Passwords</b>: Decreased risk of security incidents related to passwords.…”
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10989
Genomic DNA yield and integrity obtained from MDR-TB and DS-TB isolate cultures.
Published 2025“…A) DNA yields extracted from MGIT tubes over time; there was no change in MDR-TB DNA yield, but the DS-TB isolate yield decreased. …”
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10990
Fig 10 -
Published 2024“…The concentrations of P-HNL Dimer decreased significantly (p<0.00001, Wilcoxon´s test) at day 3 in contrast to the concentrations of P-PCT which remained unchanged during the follow-up period.…”
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10991
Table 1_Trends in cervical cancer incidence and mortality in the United States, 1975–2018: a population-based study.docx
Published 2025“…</p>Conclusion<p>For cervical cancer cases diagnosed in the United States from 1975 to 2018, the overall incidence and mortality rates decreased significantly. However, there was an increase in the incidence and mortality of advanced-stage squamous cell carcinoma. …”
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10992
Image 1_The gut microbiome: a vital link to hyperuricemia, gout and acute flares?.pdf
Published 2025“…The abundances of Bacteroides and Lachnospira genera decreased in the acute gout stage.</p>Conclusion<p>Our study revealed that community richness and diversity change during the process of gout or HUA, especially during acute gout flares. …”
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10993
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10994
Deactivation mechanism of catalyst in long-period experiment of 1,1,2-TCE dehydrochlorination
Published 2024“…The results indicated that the catalyst life had been significantly improved. In the early stage of the reaction, the activity of the catalyst decreased rapidly. …”
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10995
Advanced experimental investigation of explosive characteristics in premixed syngas/air mixtures using a narrow gap disk burner
Published 2025“…The results show that the folding of the flame front is enhanced as the Φ decreases. However, the change in fold degree is negligible when the Φ decreases from 1.6 to 1.2. …”
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10996
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10997
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10998
Data Sheet 1_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.docx
Published 2025“…The serum metabolic profile of IAV patients was significantly changed, and the purine metabolism was destroyed. …”
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10999
Image 2_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg
Published 2025“…The serum metabolic profile of IAV patients was significantly changed, and the purine metabolism was destroyed. …”
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11000
Image 5_Characterization of serum metabolome and respiratory microbiota in children with influenza A virus infection.jpeg
Published 2025“…The serum metabolic profile of IAV patients was significantly changed, and the purine metabolism was destroyed. …”