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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant changes » significant challenge (Expand Search)
changes decrease » larger decrease (Expand Search), largest decrease (Expand Search), change increases (Expand Search)
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18381
Baseline characteristics of the study population.
Published 2025“…Widespread use of the measles vaccine has decreased measles antibody potency in the United States plasma supply. …”
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18382
Table3_Use of non-specific immunoglobulins in Catalonia in three third-level hospitals: a descriptive analysis of a hospital-prescribed medication registry.docx
Published 2024“…In the sensitivity analysis, the A-level usage rate decreased to one-third and the B-level usage rate increased by 2–3 times. …”
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18383
Supplementary file 2_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx
Published 2025“…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV<sub>1</sub>), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …”
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18384
Table 1_Global, regional, and national anemia burden among women of reproductive age (15–49 years) from 1990 to 2021: an analysis of the Global Burden of Disease Study 2021.docx
Published 2025“…Background<p>Anemia remains a significant global health challenge, disproportionately affecting women of reproductive age (WRA, 15 to 49 years) due to physiological and socioeconomic factors. …”
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18385
Table 5_Multi-omics reveals effects of diet FNDF/starch level on growth performance and rumen development of Hu sheep.xlsx
Published 2025“…The results indicated that average daily gain (ADG) and average daily feed intake (ADFI) of group B, C and D were significantly higher than group A (p < 0.05); the feed conversion ratio (FCR) of group B was significantly higher than other groups (p < 0.05) and the height of rumen papillae in group B and C was significantly higher than in group A (p < 0.05). …”
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18386
DataSheet1_Mechanism of Valeriana officinalis L. extract improving atherosclerosis by regulating PGC-1α/Sirt3/Epac1 pathway.pdf
Published 2025“…Furthermore, the drug significantly increased the mRNA and protein expression of PGC-1α and Sirt3 in aortic tissue, while decreasing the mRNA and protein expression of Epac1, Caspase-3, and Caspase-9.…”
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18387
DataSheet1_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.zip
Published 2024“…Although the population of F4/80<sup>+</sup>CD11b<sup>+</sup> intrahepatic mononuclear phagocytes remained unchanged, their infiltration and activation (CHIT1<sup>+</sup>MerTK<sup>+</sup>) significantly decreased in OATD-01-treated mice, compared with that observed in vehicle-treated mice.…”
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18388
Image 2_Multi-omics reveals effects of diet FNDF/starch level on growth performance and rumen development of Hu sheep.tif
Published 2025“…The results indicated that average daily gain (ADG) and average daily feed intake (ADFI) of group B, C and D were significantly higher than group A (p < 0.05); the feed conversion ratio (FCR) of group B was significantly higher than other groups (p < 0.05) and the height of rumen papillae in group B and C was significantly higher than in group A (p < 0.05). …”
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18389
Supplementary file 1_Bioinformatics analysis combined with experimental validation reveals the novel mechanisms of multi-targets of dapagliflozin attenuating diabetic liver injury....
Published 2025“…Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, has shown significant therapeutic benefits in clinical trials for the management of diabetes However, the specific mechanism on the treatment of diabetic liver injury with dapagliflozin is not fully understood. …”
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18390
Image 1_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.png
Published 2025“…ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”
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18391
Data Sheet 1_Sex differences in burnout and work-family conflict among Chinese emergency nurses: a cross-sectional study.docx
Published 2024“…Multiple linear regression analyses indicated that three dimensions of burnout including emotional exhaustion, depersonalization, and reduced work accomplishment significantly affected work–family role behavior conflict in both sexes. …”
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18392
Supplementary file 1_Effects of external diaphragm pacing combined with repetitive peripheral magnetic stimulation of the phrenic nerve on respiratory function in stroke patients.p...
Published 2025“…In all three groups, CMAP amplitude increased significantly, whereas PNCT decreased significantly (p < 0.05). …”
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18393
Image 6_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff
Published 2025“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. …”
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18394
Table 1_Effect of high-intensity intermittent rehabilitation training on physical function, gut microbiome and metabolite after percutaneous coronary intervention in patients with...
Published 2024“…</p>Results<p>The 6MWT showed significantly greater improvement in the HIIT group compared to the MCT group (P = 0.0024). …”
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18395
Data Sheet 2_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf
Published 2025“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. However, only age, hindlimb joint pain, and hindlimb muscle atrophy had statistically significant effects on physical activity.…”
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18396
Data Sheet 1_Preliminary evaluation of a novel serotype O foot-and-mouth disease mRNA vaccine.docx
Published 2025“…The viral load results demonstrated that the vaccine group significantly reduced viral copy numbers in serum and effectively decreased the concentration of the inflammatory cytokine IL-1β. …”
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18397
Table 1_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx
Published 2025“…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …”
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18398
Prognostic value of cardiac troponin I in acute ischemic stroke patients treated with reperfusion therapy: a multicenter retrospective cohort study
Published 2025“…Elevated cTnI was not significantly associated with sICH (OR:3.75, 95%CI 0.52–27.21, <i>p</i> = 0.19), but was independently associated with increased in-hospital mortality (OR:1.96, 95%CI 1.62–6.20, <i>p</i> = 0.025) and decreased odds of good functional outcome at 30 days (OR:0.40, 95%CI 0.19–0.84, <i>p</i> = 0.016). …”
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18399
Dataset with aluminium insert.
Published 2024“…It focuses on identifying and quantifying clinically significant materials in the presence of metal objects. …”
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18400
A review of geological characteristics and selenium enrichment in Se-bearing volcanogenic massive sulfide deposits
Published 2024“…<p>Volcanogenic massive sulphide (VMS) deposits consist of upper stratabound massive-to-semimassive sulphide lenses and discordant stringer sulphides in the footwall, hosting significant base metals like Zn, Cu, and Pb, with some enriched in precious (Ag, Au) and semi-metals (like Se and Te). …”