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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significant changes » significant challenge (Expand Search)
changes decrease » larger decrease (Expand Search), largest decrease (Expand Search), change increases (Expand Search)
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18461
Data Sheet 1_Prognostic model construction and immune microenvironment analysis of pyroptosis-related genes in hepatocellular carcinoma based on single-cell RNA sequencing.zip
Published 2025“…Although pyroptosis plays a critical role in tumor-immune interactions, its prognostic significance in HCC at single-cell resolution has not been systematically investigated.…”
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18462
Image 5_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa...
Published 2025“…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”
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18463
Table 8_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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18464
Data Sheet 1_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.pdf...
Published 2025“…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. …”
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18465
3D Nanoscale Structures of Hydrated Polyamide Desalination Membranes Revealed by Cryogenic Transmission Electron Microscopy Tomography
Published 2025“…Our findings reveal significant morphological differences between hydrated and dry membranes, resulting in variations in key structural parameters that impact performance. …”
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18466
Data Sheet 1_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through a...
Published 2025“…Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”
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18467
Image 1_L1, a 3,3′-diindolylmethane-derivative, induced ER stress-mediated apoptosis and suppressed growth through the FLI1/AKT pathway in erythroleukemia HEL cells.tif
Published 2025“…Moreover,the inhibition rate was decreased in the HSPA1A knockdown HEL cells, suggesting that L1-induced apoptosis was related to HSP70 activity. …”
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18468
Table 1_Biological characterization of novel Escherichia coli O157:H7 phages and their bacteriostatic effects in milk and pork.xlsx
Published 2025“…<p>Foodborne bacteria, particularly Escherichia coli (E. coli) O157:H7, are significant contributors to foodborne illnesses, with antibiotic overuse exacerbating the issue through the emergence of multidrug-resistant strains. …”
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18469
Data Sheet 1_Biological characterization of novel Escherichia coli O157:H7 phages and their bacteriostatic effects in milk and pork.pdf
Published 2025“…<p>Foodborne bacteria, particularly Escherichia coli (E. coli) O157:H7, are significant contributors to foodborne illnesses, with antibiotic overuse exacerbating the issue through the emergence of multidrug-resistant strains. …”
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18470
Image 2_L1, a 3,3′-diindolylmethane-derivative, induced ER stress-mediated apoptosis and suppressed growth through the FLI1/AKT pathway in erythroleukemia HEL cells.tif
Published 2025“…Moreover,the inhibition rate was decreased in the HSPA1A knockdown HEL cells, suggesting that L1-induced apoptosis was related to HSP70 activity. …”
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18471
Table 2_Biological characterization of novel Escherichia coli O157:H7 phages and their bacteriostatic effects in milk and pork.xlsx
Published 2025“…<p>Foodborne bacteria, particularly Escherichia coli (E. coli) O157:H7, are significant contributors to foodborne illnesses, with antibiotic overuse exacerbating the issue through the emergence of multidrug-resistant strains. …”
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18472
Fig 10 -
Published 2024“…The concentrations of P-HNL Dimer decreased significantly (p<0.00001, Wilcoxon´s test) at day 3 in contrast to the concentrations of P-PCT which remained unchanged during the follow-up period.…”
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18473
Figure 3 from A Cost-Effective Two-Step Approach for Multi-Cancer Early Detection in High-Risk Populations
Published 2025“…In the case–control cohort, the two-step MCED approach significantly improved specificity from 91.0% to 99.3%, whereas sensitivity decreased from 49.9% to 39.9%. …”
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18474
Expression of <i>SHH</i> in the FEZ after RCAS-virus infection to induce overexpression and knockdown of <i>PBX1</i> and <i>PBX3.</i>
Published 2025“…Statistical significance was determined at P-value < 0.05; *, P < 0.05; **, P < 0.01; ****, P < 0.0001; ns, not significant.…”
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18475
Data Sheet 1_Administration of anticoagulation strategies for portal vein thrombosis in cirrhosis: network meta-analysis.docx
Published 2025“…Warfarin and TIPS were recommended for reducing the frequency of bleeding events, while LMWH plus warfarin and DOACs proved to be most effective in decreasing the rate of major bleeding events. Warfarin, heparin plus DOACs plus warfarin, and DOACs demonstrated the most significant reduction in mortality rates, highlighting its potential as an effective intervention. …”
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18476
Table_1_Psychological wellbeing among carers of children and adolescents with physical disabilities in North-Eastern Tanzania—a cross-sectional survey study.docx
Published 2024“…Notably, poor psychological wellbeing was significantly associated with symptoms of anxiety and depression. …”
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18477
Evolutionary tree analysis of ZmSTOMAGEN.
Published 2025“…Compared to the wild-type plants (HiII-A × HiII-B), the <i>zmstomagen1/2</i> mutant exhibited significant alterations in phytohormone homeostasis. …”
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18478
Table_1_Effect of progesterone concentration on hCG trigger day on clinical outcomes after high-quality single blastocyst transfer in GnRH antagonist cycles.docx
Published 2024“…And the pregnancy rate decreased by 25% (95% CI: 0.51, 1.09) for frozen cycles, although there was no statistically significant (p = 0.1273). …”
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18479
Data Sheet 1_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.pdf
Published 2025“…Healthy control also showed globally increased [<sup>18</sup>F]SMBT-1 uptake. There was no significant correlation between the degree of [<sup>18</sup>F]FDOPA uptake and [<sup>18</sup>F]SMBT-1 uptake in any brain region.…”
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18480
Table 1_Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients.doc
Published 2025“…We identified two epitopes associated with decreased CD8 T-cell reactivity post-Omicron variant emergence. …”