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significant changes » significant genes (Expand Search), significant clusters (Expand Search)
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significant changes » significant genes (Expand Search), significant clusters (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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61
The effect of acute ophiobolin A treatment on HO-mediated inflammatory processes
Published 2017“…We found that OPA caused a significant elevation in the concentrations of IL-6 and TNF-, increased MPO activity and decreased HO enzyme activity in the plasma. …”
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62
Effect of Bariatric Surgery on Serum Amyloid A Protein: a Systematic Review and Meta-analysis
Published 2023“…Conclusion: Bariatric surgery significantly improved SAA. The decrease in SAA was not related to time after surgery or changes in BMI. …”
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63
Effect of hyperlipidemia on ketoconazole-midazolam drug-drug interaction in rat
Published 2011“…With KTZ coadministered to hyperlipidemic rats, there were significant decreases in MDZ CL and VD. HL caused a decrease in unbound plasma fraction of oral KTZ but no significant difference in its pharmacokinetics. …”
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64
Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain
Published 2022“…In addition, nicotine individually decreased expression levels of all examined protein targets, significantly for CYP1B1 (p < 0.001), CYP19A1 (p = 0.010), AhRR (p = 0.042), and ARNT (p < 0.001), compared to control. …”
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65
Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
Published 2023“…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …”
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66
Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
Published 2023“…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …”
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67
Comparative skull analysis suggests species-specific captivity-related malformation in lions (Panthera leo)
Published 2014“…Lion (Panthera leo) populations have dramatically decreased worldwide with a surviving population estimated at 32,000 across the African savannah. …”
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68
Changes in expression of Kv7.5 and Kv7.2 channels in dorsal root ganglion neurons in the streptozotocin rat model of painful diabetic neuropathy
Published 2020“…We found 35 days post-STZ: (1) a significant decrease in Kv7.5-immunoreactivity in small (<30 μm) DRG neurons (both IB4 positive and IB4 negative) and medium-sized (30−40 μm) neurons, and (2) a significant increase in Kv7.2-immunoreactivity in small (<30 μm) neurons, and a non-significant increase in medium/large neurons. …”
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69
The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells.
Published 2019“…Pb treatment induced oxidative stress by a) increasing the formation of reactive oxygen species and b) decreasing GSTA1 mRNA levels. …”
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70
Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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71
Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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72
Mangifera indica L. kernel ethanol extract inhibits cell viability and proliferation with induction of cell cycle arrest and apoptosis in lung cancer cells
Published 2024“…Furthermore, the extract exhibited higher toxicity towards NCI-H292 cells, followed by A549 and normal MRC-5 cells in decreasing order of potency. …”
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73
Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …”
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74
Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …”
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75
Short-term effects of warming treatment and precipitation manipulation on the ecophysiological responses of pinus densiflora seedlings
Published 2016“…The three precipitation manipulations consisted of decreased precipitation using transparent panels (–30%; P–), increased precipitation using pumps and drip irrigation (+30%; P+), and a control (0%; P0). …”
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76
Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects
Published 2019“…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …”
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77
Associations of Recreational and Nonrecreational Physical Activity and Body Weight Change on Cardiovascular Disease Mortality During the Obesogenic Transition in the United States:...
Published 2023“…We found weak (but nonstatistically significant) evidence of mediation effects of body weight change on mortality. …”
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78
Short-Term Effects of Experimental Warming and Precipitation Manipulation on Soil Microbial Biomass C and N, Community Substrate Utilization Patterns and Community Composition
Published 2017“…Decreased and increased precipitation significantly reduced microbial biomass C by 13.5% and 24.9% and microbial biomass N by 22.9% and 17.6% in unwarmed plots, respectively (P < 0.01). …”
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79
Responses of lichen communities to 18 years of natural and experimental warming
Published 2017“…Lichen cover, species richness, effective number of species evenness were negatively correlated with plant canopy cover. There was a significant negative impact on one species and a non-significant tendency of lower abundance of the most common species in response to experimental warming. …”
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80
Bryophyte cover and richness decline after 18 years of experimental warming in alpine Sweden.
Published 2020“…Species abundance was measured in 1995, 1999, 2001 and 2013. Species composition changed significantly from original communities in the heath, but remained similar in mesic meadow. …”
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