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significant changes » significant challenge (Expand Search)
changes decrease » largest decrease (Expand Search), change increases (Expand Search)
linear decrease » linear increase (Expand Search)
larger decrease » marked decrease (Expand Search)
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7701
Image 2_Ferrostatin-1 improves acute sepsis-induced cardiomyopathy via inhibiting neutrophil infiltration through impaired chemokine axis.jpeg
Published 2024“…Pretreating the CLP mice with 5 mg/kg Fer-1 significantly reduced mortality. At 6h after CLP, ferroptosis key regulator Gpx4, cardiac iron and malonaldehyde (MDA) did not change, but ferroptosis marker gene expression increased. …”
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7702
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7703
Alternative therapeutic strategy for existing aortic aneurysms using mesenchymal stem cell–derived exosomes
Published 2025“…In the MSC-ex group, the expression of IL-1β, TNF-α and MCP-1 decreased, and expression of IGF-1 and TIMP-2 increased. …”
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7704
Table_1_Predicting cancer-related mycobiome aspects in gastrointestinal cancers: a systematic review.docx
Published 2024“…Observing the interindividual variability, we found that the Ascomycota/Basidiomycota (A/B) ratio from healthy to cancer state decreased in n = 2, increased in n = 1 cases, and did not change significantly in n = 2 studies. …”
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7705
Data_Sheet_1_Predicting cancer-related mycobiome aspects in gastrointestinal cancers: a systematic review.DOCX
Published 2024“…Observing the interindividual variability, we found that the Ascomycota/Basidiomycota (A/B) ratio from healthy to cancer state decreased in n = 2, increased in n = 1 cases, and did not change significantly in n = 2 studies. …”
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7706
Data Sheet 1_Seaweed (Porphyra) cultivation enhances production of autochthonous refractory dissolved organic matter in coastal ecosystems.docx
Published 2025“…Dissolved organic carbon (DOC) concentration was significantly elevated during the cultivation versus non-cultivation period, while particulate organic carbon (POC) concentration decreased, thereby resulting in a higher DOC/POC ratio in the water column. …”
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7707
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7708
Data Sheet 1_Global, regional, and national burden of ischemic heart disease attributed to non-optimal temperature, 1990–2021: an age-period-cohort analysis of the global burden of...
Published 2025“…Background<p>In recent years, non-optimal temperature has significantly impacted global health including ischemic heart disease (IHD).…”
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7709
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7710
Figure 2 from mTORC1-Driven Protein Translation Correlates with Clinical Benefit of Capivasertib within a Genetically Preselected Cohort of <i>PIK3CA</i>-Altered Tumors
Published 2025“…Nodes are overlaid from the Cytoscape visualization, with fold-change shown by color. Node size increases as the <i>P</i>-value decreases. …”
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7711
Table 2_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.csv
Published 2025“…The secular trends were characterized using the average annual percentage change (AAPC), while the impact of the COVID-19 pandemic was assessed through the estimated annual percentage change (EAPC).…”
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7712
Table 1_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.csv
Published 2025“…The secular trends were characterized using the average annual percentage change (AAPC), while the impact of the COVID-19 pandemic was assessed through the estimated annual percentage change (EAPC).…”
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7713
Image 1_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.tiff
Published 2025“…The secular trends were characterized using the average annual percentage change (AAPC), while the impact of the COVID-19 pandemic was assessed through the estimated annual percentage change (EAPC).…”
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7714
Table 3_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.csv
Published 2025“…The secular trends were characterized using the average annual percentage change (AAPC), while the impact of the COVID-19 pandemic was assessed through the estimated annual percentage change (EAPC).…”
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7715
Table 4_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.xlsx
Published 2025“…The secular trends were characterized using the average annual percentage change (AAPC), while the impact of the COVID-19 pandemic was assessed through the estimated annual percentage change (EAPC).…”
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7716
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7717
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7718
Table 1_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.docx
Published 2025“…</p>Results<p>New functional morbidity occurred in 38 children (32%) and was associated with increased plasma levels of interleukin (IL)-6, IL-18, sIL-2Ra, MCP1, IL-8 (CXCL8), sIL-1RII, IL-10, MIP1a, and IL-2r and decreased RANTES (CCL5) (p < .001) at all three timepoints. …”
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7719
Table 2_Epidemiological trends and disparities in iodine, vitamin A, and iron deficiencies among children aged 0–14 years globally, 1990–2021.docx
Published 2025“…Vitamin A deficiency incidence rate decreased by 94.9% (EAPC: −2.02), while DALY rates fell 92.8%. …”
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7720