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significant changes » significant challenge (Expand Search)
changes decrease » larger decrease (Expand Search), largest decrease (Expand Search), change increases (Expand Search)
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7021
Data Sheet 3_Identification of the malonylation modification in Staphylococcus aureus and insight into the regulators in biofilm formation.pdf
Published 2025“…</p>Methods<p>In this study, we analyzed the dynamic changes of protein malonylation of Staphylococcus aureus (S. aureus) DC15 during biofilm formation based on antibody affinity enrichment combined with quantitative proteomics.…”
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7022
Data Sheet 2_Identification of the malonylation modification in Staphylococcus aureus and insight into the regulators in biofilm formation.xlsx
Published 2025“…</p>Methods<p>In this study, we analyzed the dynamic changes of protein malonylation of Staphylococcus aureus (S. aureus) DC15 during biofilm formation based on antibody affinity enrichment combined with quantitative proteomics.…”
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7023
Data Sheet 1_Comprehensive analysis on the regulatory mechanism of active ingredient accumulation during fermentation process of Massa Medicata Fermentata: microbe and metabolic pr...
Published 2025“…Background<p>Massa Medicata Fermentata (MMF) is a traditional medicinal/edible fermented product; however, comprehensive research on the fermentation process from a microscopic perspective remains limited. In this study, we aimed to investigate the dynamic changes and correlations of physicochemical properties, microbial communities, and metabolite profiles in different fermentation stages (0, 48, 72, and 96 h) of MMF.…”
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7024
Table 1_Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.xlsx
Published 2025“…</p>Methods<p>Utilizing data from the GBD Study 2021 on the incidence and disability-adjusted life-years (DALYs) of Alzheimer’s disease (AD) and other dementias, Parkinson’s disease, multiple sclerosis, and idiopathic epilepsy in women from 1990 to 2021. We estimated trends by age and socio-demographic index (SDI), globally, regionally, and nationally, using Estimated annual percentage changes (EAPC), Spearman correlation analysis and projected future trends with the Bayesian age-period-cohort (BAPC) model.…”
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7025
Data Sheet 1_Sleep is enhanced in aged male mice that overexpress calcium/calmodulin-dependent protein kinase IV.docx
Published 2025“…Using 2- to 4-month-old (young adult) and 22- to 24-month-old (aged) male and female CaMKIV-overexpressing (CaMKIV-OE) mice, we observed that overexpression of CaMKIV in the forebrain decreased wakefulness and increased the amount of non-rapid eye movement (NREM) and rapid eye movement (REM) sleep in aged male mice, but not young adult male mice, in comparison to age- and sex-matched controls. …”
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7026
Supplementary file 1_Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.docx
Published 2025“…</p>Methods<p>Utilizing data from the GBD Study 2021 on the incidence and disability-adjusted life-years (DALYs) of Alzheimer’s disease (AD) and other dementias, Parkinson’s disease, multiple sclerosis, and idiopathic epilepsy in women from 1990 to 2021. We estimated trends by age and socio-demographic index (SDI), globally, regionally, and nationally, using Estimated annual percentage changes (EAPC), Spearman correlation analysis and projected future trends with the Bayesian age-period-cohort (BAPC) model.…”
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7027
Image 1_Fraxin modulates lipid metabolism as well as gut flora to avert NAFLD.tif
Published 2025“…GO and KEGG analyses suggested that fraxin primarily treats NAFLD by modulating lipid metabolism and atherosclerosis-related signaling pathways. In vivo, fraxin significantly lowered liver index and visceral fat accumulation, reduced serum levels of “interleukin-6 (IL-6),” “aspartate aminotransferase,” “tumor necrosis factor-α (TNF-α)” and “alanine aminotransferase,” and decreased hepatic TG content. …”
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7028
Table 1_Housed feeding improves rumen health by influencing the composition of the microbiota in Honghe cattle.docx
Published 2025“…For rumen microbiota, the HES group significantly decreased alpha diversity. The core rumen bacterial communities were Bacteroidata, Firmicutes and Proteobacteria. …”
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7029
Data Sheet 1_Tuberculosis disease burden in China: a spatio-temporal clustering and prediction study.docx
Published 2025“…Tibet (124.24%) and Xinjiang (114.72%) in western China exhibited the largest percentage change in tuberculosis (TB) incidence, while Zhejiang Province (−50.45%) and Jiangsu Province (−51.33%) in eastern China showed the largest decreases. …”
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7030
Data Sheet 2_Tuberculosis disease burden in China: a spatio-temporal clustering and prediction study.docx
Published 2025“…Tibet (124.24%) and Xinjiang (114.72%) in western China exhibited the largest percentage change in tuberculosis (TB) incidence, while Zhejiang Province (−50.45%) and Jiangsu Province (−51.33%) in eastern China showed the largest decreases. …”
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7031
Data Sheet 1_Treatment with pemafibrate ameliorates fatty liver index and atherogenic lipid profiles in Japanese patients with type 2 diabetes mellitus.pdf
Published 2025“…There was no significant change in hemoglobin A1c level over time. …”
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7032
Supplementary Material for: A Randomized Controlled Crossover Trial to Determine the Effects of Three Nostril Regulated Breathing Practices on Attention and Mood
Published 2025“…A significant main effect of states was observed followed by significant post-hoc pair wise comparison in right NDR for (i) pleasant mood after SAV, CAV, AV and QS, (ii) positive mood after SAV and AV, and (iii) global vigor after SAV, CAV, AV and QS, and (iv) a decrease in negative mood after CAV and AV. …”
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7033
Association of lactate-albumin ratio with native liver survival in paediatric acute liver failure: a 10-year retrospective study
Published 2025“…</p> <p>Among 77 patients, 46.8% (36 cases) had SNL, with 14.3% (11 cases) requiring transplantation. A significant decrease in SNL was associated with higher LAR (<i>p</i> = 0.005), with a 4% decline in SNL for each 1% increase in LAR. …”
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7034
Data Sheet 1_Plausibility of super high-flux dialyzer reuse in maintenance hemodialysis.pdf
Published 2025“…</p>Conclusion<p>Super high-flux dialyzers reuse is a safe and promising method to reduce medical waste and manufacturing costs while maintaining the benefits of this novel HD technique. We also suggest appropriate cut-off points for the change in RR of the middle-molecule uremic toxin after reuse to prevent significant impairment in solute clearances.…”
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7035
Table 2_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx
Published 2025“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”
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7036
The MIC values of DDAB for the different strains.
Published 2025“…In an <i>in vivo</i> mice model, the virulence of Δ<i>sugE2</i> and Δ<i>sugE1</i>Δ<i>sugE2</i> mutant strains were enhanced and showed significantly increased bacterial loads in the liver, spleen, and cecum. …”
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7037
Table 1_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx
Published 2025“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”
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7038
Data Sheet 1_Pregnancy and contraceptive use among participants of childbearing potential in the HVTN 705 HIV vaccine trial in Southern Africa.docx
Published 2025“…Nevertheless, some pregnancies occur in almost all studies. We examined contraceptive use, pregnancy incidence, and the relationship between pregnancy and HIV seroconversion in one HIV vaccine trial.…”
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7039
Table 3_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.docx
Published 2025“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”
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7040
Image 1_Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients.jpg
Published 2025“…Finally, treatment with anti-IL-23 led to a reduction in visfatin levels in female psoriatic patients and resulted in a significant decrease in fat mass percentage in men. …”