Image_3_Validation and analysis of expression, prognosis and immune infiltration of WNT gene family in non-small cell lung cancer.jpeg by Jianglin Wang (1569508)

“…Compared with that of normal tissues, WNT2/2B/3A/4/7A/9A/9B/11 expressions decreased, while WNT3/5B/6/7B/8B/10A/10B/16 expressions increased in lung adenocarcinoma (LUAD); WNT2/3A/7A/11 expressions were lessened, while WNT2B/3/5A/5B/6/7B/10A/10B/16 expressions were enhanced in squamous cell lung cancer (LUSC). …”

Image_1_TGF-β2 Induces Gli1 in a Smad3-Dependent Manner Against Cerebral Ischemia/Reperfusion Injury After Isoflurane Post-conditioning in Rats.TIF by Li Peng (83452)

“…When TGF-β2 inhibitor, pirfenidone, or Smad3 inhibitor, SIS3 HCl, were administered, the expression levels of p-Smad3 and Gli1 were reduced, and surviving pyramidal neurons decreased. By contrast, the expression levels of TGF-β2 and p-Smad3 did not change significantly after pre-injection of Smo inhibitor cyclopamine, but reduced the expression levels of Shh, Ptch, and Gli1. …”

Table_5_Transcriptome analysis provides insight into the regulatory mechanisms underlying pollen germination recovery at normal high ambient temperature in wild banana (Musa itiner... by Chunyu Zhang (118320)

“…The cysteine content, free fatty acid (FFA) content, H₂O₂ content, fructose content, and sucrose content of pollen were increased at treatment of 28°C, while D-Golactose content was decreased. …”

Image2_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif by Zi Yang (276531)

“…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

Table_4_Transcriptome analysis provides insight into the regulatory mechanisms underlying pollen germination recovery at normal high ambient temperature in wild banana (Musa itiner... by Chunyu Zhang (118320)

“…The cysteine content, free fatty acid (FFA) content, H₂O₂ content, fructose content, and sucrose content of pollen were increased at treatment of 28°C, while D-Golactose content was decreased. …”

Table_4_TGF-β2 Induces Gli1 in a Smad3-Dependent Manner Against Cerebral Ischemia/Reperfusion Injury After Isoflurane Post-conditioning in Rats.XLS by Li Peng (83452)

“…When TGF-β2 inhibitor, pirfenidone, or Smad3 inhibitor, SIS3 HCl, were administered, the expression levels of p-Smad3 and Gli1 were reduced, and surviving pyramidal neurons decreased. By contrast, the expression levels of TGF-β2 and p-Smad3 did not change significantly after pre-injection of Smo inhibitor cyclopamine, but reduced the expression levels of Shh, Ptch, and Gli1. …”

Image_12_TGF-β2 Induces Gli1 in a Smad3-Dependent Manner Against Cerebral Ischemia/Reperfusion Injury After Isoflurane Post-conditioning in Rats.TIF by Li Peng (83452)

“…When TGF-β2 inhibitor, pirfenidone, or Smad3 inhibitor, SIS3 HCl, were administered, the expression levels of p-Smad3 and Gli1 were reduced, and surviving pyramidal neurons decreased. By contrast, the expression levels of TGF-β2 and p-Smad3 did not change significantly after pre-injection of Smo inhibitor cyclopamine, but reduced the expression levels of Shh, Ptch, and Gli1. …”

DataSheet_1_Lnc-AIFM2-1 promotes HBV immune escape by acting as a ceRNA for miR-330-3p to regulate CD244 expression.docx by Chengxia Xie (14589125)

“…The results showed that the expression of CD244 on the surface of CD8⁺ T cells was significantly increased in CHB patients and in the co-culture system of T cells and HBV-infected HepAD38 cells, which was accompanied by the reduction of miR-330-3p and the elevation of lnc-AIFM2-1. …”

Data_Sheet_4_Circulating exo-miR-154-5p regulates vascular dementia through endothelial progenitor cell-mediated angiogenesis.XLSX by Xue Han (25073)

“…In addition, miRNA-154-5p inhibition increased the level of superoxide dismutase (SOD), and decreased reactive oxygen species (ROS) in EPCs. …”

Table1_Small-molecule BCL6 inhibitor protects chronic cardiac transplant rejection and inhibits T follicular helper cell expansion and humoral response.DOCX by Yuxuan Xia (14800378)

“…</p><p>Results: We found that the Tfh cells were significantly increased in the recipient mice on day 14 post transplantation. …”

Data Sheet 2_Combined inhibition of dopamine D1/D2 receptors induces cognitive and emotional dysfunction through oxidative stress and dopaminergic neuron damage.zip by Xue Li (285380)

“…</p>Results<p>Low-dose co-DR1/2I significantly increased MAO-B and ROS levels (p < 0.01) and decreased SOD activity (p < 0.01) in the substantia nigra, striatum, and hippocampus. …”

Table_5_Identification and Clinical Validation of Key Extracellular Proteins as the Potential Biomarkers in Relapsing-Remitting Multiple Sclerosis.xlsx by Meng Li (79487)

“…We clinically verified that IL17A levels decreased, but Del-1 and resolvinD1 levels increased. …”

Table_2_miR-22 and miR-205 Drive Tumor Aggressiveness of Mucoepidermoid Carcinomas of Salivary Glands.docx by Erika Naakka (12062924)

“…The integrative miRNA-mRNA analysis revealed a network comprising 696 negatively correlated interactions (44 miRNAs and 444 mRNAs) involving cell signaling, cell cycle, and cancer-related pathways. Increased expression levels of miR-205-5p and miR-224-5p and decreased expression levels of miR-139-3p, miR-145-3p, miR-148a-3p, miR-186-5p, miR-338-3p, miR-363-3p, and miR-4324 were significantly related to worse overall survival in MEC patients. …”

Changes in dorsal-ventral patterning of CA1 in COUP-TFI mutant hippocampus. by Ching-San Tseng (6252566)

“…The Dcn/Wfs1 ratio was significantly decreased in the cKO and increased in the cTG. …”

Analysis of <i>n</i>(⁸⁷Sr)/<i>n</i>(⁸⁶Sr), <i>δ</i>⁸⁸Sr/⁸⁶Sr_SRM987 and elemental pattern to characterise groundwater and rech... by Anastassiya Tchaikovsky (6502235)

“…The <i>n</i>(⁸⁷Sr)/<i>n</i>(⁸⁶Sr) ratio and elemental pattern changed with aquifer depth as a result of progressing bedrock leaching and dissolution with increasing groundwater residence time. The <i>n</i>(⁸⁷Sr)/<i>n</i>(⁸⁶Sr) ratio of shallow groundwater below saline ponds of 0.71019 ± 0.00044 was significantly different from thermal groundwater of 0.71205 ± 0.00035 (<i>U</i>, <i>k </i>= 2). …”

Table_8_Transcriptome analysis provides insight into the regulatory mechanisms underlying pollen germination recovery at normal high ambient temperature in wild banana (Musa itiner... by Chunyu Zhang (118320)

“…The cysteine content, free fatty acid (FFA) content, H₂O₂ content, fructose content, and sucrose content of pollen were increased at treatment of 28°C, while D-Golactose content was decreased. …”

Image_5_Patients with advanced pancreatic and biliary cancer appear vulnerable to SARS-CoV-2 Omicron variant: An observational study during the COVID-19 outbreak in Shanghai.tif by Tao Han (22342)

“…Time-course cytokine monitoring results showed that IL-1β was significantly decreased in Group 1 (P <0.05) and generally kept at a low level without obvious fluctuation. …”

Table_1_Efficacy and safety of immunotherapy combined with single-agent chemotherapy as second- or later-line therapy for metastatic non-small cell lung cancer.docx by Dongna Chen (16999068)

“…In addition, VEGFR2 expression was increased after combined immunotherapy in responders, which was decreased in non-responders. …”

Image_2_The Diagnostic Potential of SHOX2 and RASSF1A DNA Methylation in Early Lung Adenocarcinoma.tif by Hong Gao (68166)

“…In both cohorts, SHOX2 expression increased and RASSF1A expression decreased in tumor samples. …”

Data Sheet 3_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf by Yufei Li (433737)

“…It ameliorated MAMs ultrastructure and function, enhancing CypD, MCU, Sig-1R, and NOGO-B expression while reducing IP3R2, GRP75, and VDAC1. in vitro, YQHX significantly increased viability, reduced oxygen-glucose deprivation-induced mPTP opening and Ca²⁺ levels, upregulated CypD, MCU, Sig-1R, and NOGO-B, and downregulated IP3R2, GRP75, and VDAC1. …”