DataSheet_1_AURKA inhibitor-induced PD-L1 upregulation impairs antitumor immune responses.docx by Bi Meng (16970205)

“…When treated with MLN8237 in combination with anti-PD-L1 antibody, the volumes of tumor were significantly reduced and accompanied by increasing the infiltration of CD3+ and CD8+ T cells in colorectal cancer xenograft tumor model.…”

Data_Sheet_1_Efficient Secretion and Recombinant Production of a Lactobacillal α-amylase in Lactiplantibacillus plantarum WCFS1: Analysis and Comparison of the Secretion Using Diff... by Anh-Minh Tran (3712471)

“…These yields were significantly higher than the expression and secretion in L. plantarum WCFS1 using the native signal peptide SP_AmyL, resulting in 6.2- and 5.4-fold increase in total and extracellular activities of AmyL, respectively. …”

Table_1_Comparative Food Web Analysis of Two Peruvian Bay Systems Along a Latitudinal Gradient: Resource Use and the Environmental Envelope.XLSX by Alonso Del Solar (12320237)

“…Chlorophyll concentrations have risen significantly in both systems, higher values in Sechura suggesting there is an increase in local pressures that could lead to eutrophication. …”

Image_2_Patient-Derived Organoid Serves as a Platform for Personalized Chemotherapy in Advanced Colorectal Cancer Patients.jpeg by Khamushavalli Geevimaan (12705392)

Image_1_Efficient Secretion and Recombinant Production of a Lactobacillal α-amylase in Lactiplantibacillus plantarum WCFS1: Analysis and Comparison of the Secretion Using Different... by Anh-Minh Tran (3712471)

“…These yields were significantly higher than the expression and secretion in L. plantarum WCFS1 using the native signal peptide SP_AmyL, resulting in 6.2- and 5.4-fold increase in total and extracellular activities of AmyL, respectively. …”

Data_Sheet_2_A Comparison of Two Monoterpenoid Synthases Reveals Molecular Mechanisms Associated With the Difference of Bioactive Monoterpenoids Between Amomum villosum and Amomum... by Haiying Zhao (1788967)

“…There was only one different amino acid between AlTPS3 (A496) and AvBPPS (G495) in their conserved motifs, and the site-directed mutation of A496G in DTE motif of AlTPS3 changed the major product from camphene to BPP. Molecular docking suggests that A496G mutation narrows the camphene-binding pocket and decreases the BPP-binding energy, thus increases the product BPP selectivity of enzyme. …”

Data_Sheet_1_Efficient Secretion and Recombinant Production of a Lactobacillal α-amylase in Lactiplantibacillus plantarum WCFS1: Analysis and Comparison of the Secretion Using Diff... by Anh-Minh Tran (3712471)

“…These yields were significantly higher than the expression and secretion in L. plantarum WCFS1 using the native signal peptide SP_AmyL, resulting in 6.2- and 5.4-fold increase in total and extracellular activities of AmyL, respectively. …”

Quality of Family Planning Counseling in Ethiopia: Trends and determinants of information received by female modern contraceptive users, evidence from national survey data, (2014-... by Gili Hrusa (8431332)

“…</p><p>Results</p><p>The proportion of female contraception users that reported receiving information on all three questions did not significantly change over the period 2014 to 2018. Overall quality of counseling on family planning was low, with only 30% of women reporting receiving sufficient information during counseling. …”

Image_1_Tumor Growth in the High Frequency Medulloblastoma Mouse Model Ptch1+/−/Tis21KO Has a Specific Activation Signature of the PI3K/AKT/mTOR Pathway and Is Counteracted by the... by Manuela Ceccarelli (4398151)

“…Additionally, the phosphorylation of AKT, S6 and 4EBP1 was significantly inhibited, indicating inactivation of the PI3K/AKT/mTOR pathway. …”

Table_1_Tumor Growth in the High Frequency Medulloblastoma Mouse Model Ptch1+/−/Tis21KO Has a Specific Activation Signature of the PI3K/AKT/mTOR Pathway and Is Counteracted by the... by Manuela Ceccarelli (4398151)

“…Additionally, the phosphorylation of AKT, S6 and 4EBP1 was significantly inhibited, indicating inactivation of the PI3K/AKT/mTOR pathway. …”

DataSheet_1_Risk stratification for early mortality in newly diagnosed acute promyelocytic leukemia: a multicenter, non-selected, retrospective cohort study.doc by Suhyeon Kim (6715133)

Image_3_An inflammation-related gene landscape predicts prognosis and response to immunotherapy in virus-associated hepatocellular carcinoma.jpeg by Ying-jie Gao (14763901)

“…Background<p>Due to the viral infection, chronic inflammation significantly increases the likelihood of hepatocellular carcinoma (HCC) development. …”

Closed and open durations associated with human HSP or LSP α4β2-nAChR isoforms expressed in <i>X</i>. <i>laevis</i> oocytes from pentameric, fully-concatenated constructs. by Maegan M. Weltzin (6432977)

“…As was seen for unlinked subunits, increasing the ACh concentration to 30 μM did not change the number of time constants required to best fit closed <b>(C)</b> and open <b>(F)</b> duration distributions, but shortening of closed dwell durations was observed (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0213143#pone.0213143.t002" target="_blank">Table 2</a>). …”

Supplementary Material for: A Phase 3 Study of Enarodustat in Chinese Patients Undergoing Peritoneal Dialysis for Treatment of Anemia: the ENAROPERA Study by figshare admin karger (2628495)

“…Introduction: Anemia is a common complication in patients undergoing peritoneal dialysis (PD), significantly impacting quality of life and increasing cardiovascular risk. …”

Implementation of guppy fish <i>(Poecilia reticulata)</i>, and a novel larvicide (Pyriproxyfen) product (Sumilarv 2MR) for dengue control in Cambodia: A qualitative study of accept... by Muhammad Shafique (400502)

“…</p><p>Conclusions/Significance</p><p>The community led COMBI strategy resulted in high acceptance and perceived effectiveness of the interventions in target villages. …”

Table_1_Patient Reported Outcome (PRO) Among High-Grade Glioma Patients Receiving TTFields Treatment: A Two Center Observational Study.DOC by Julia Onken (6105059)

“…</p><p>Introduction: Patient reported outcome (PRO) plays an increasingly important role in the evaluation of novel therapies for tumor patients. …”

Data_Sheet_1_Assessing the Satisfaction and Acceptability of an Online Parent Coaching Intervention: A Mixed-Methods Approach.PDF by Lu Qu (4739121)

“…Background<p>Parent-mediated intervention (PMI) has been studied in promoting skill acquisition or behavior change in the children with autism spectrum disorder. …”

Data_Sheet_2_Assessing the Satisfaction and Acceptability of an Online Parent Coaching Intervention: A Mixed-Methods Approach.PDF by Lu Qu (4739121)

“…Background<p>Parent-mediated intervention (PMI) has been studied in promoting skill acquisition or behavior change in the children with autism spectrum disorder. …”

Consequences of SARS-CoV-2 infection on testis function. by Stefanos Giannakopoulos (15628394)

“…SARS-CoV-2 infection increases serum levels of pro-inflammatory cytokines/chemokines that trigger testicular inflammation leading to downstream effects including loss of BTB integrity, infiltration of immune cells, and apoptosis. …”

Supplementary Material for: Epidemiological and Treatment Trends for Acute Ischemic Stroke Preceding and during the COVID-19 Pandemic by Rodrigues A. (11465470)

“…We used 1 large national insurance database to identify whether patient demographics, disease severity, or mechanical thrombectomy (MT) rates changed for the treatment and management of AIS during COVID-19. …”