Data Sheet 1_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.docx by Zhijian Zha (19451405)

“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”

P14 <i>Rik</i>^<i>null</i> vs. WT DEGs. by Erdyni N. Tsitsikov (20384719)

“…Histological examination of anterior thalamic nuclei demonstrated decreased myelination of anteroventral nuclei but not of anterodorsal nuclei in P23 <i>Rik</i>^<i>null</i> mice. …”

DNA damage protecting effects of MEExCC. by Srabonti Saha (17452756)

“…The results demonstrated that higher doses (200 mg) of <i>C. chinense</i> methanol extract inhibited immune responses, whereas lower doses helped restore them. The extracts significantly decreased pro-inflammatory mediators and cytokines in LPS-activated macrophages. …”

Table 6_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xlsx by Zhijian Zha (19451405)

“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”

Image 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif by Rong Su (2210740)

“…In vitro, the overexpression of miR-4739 in Huh-7 cells significantly induced SPP1⁺ macrophages, and the culture medium derived from SPP1⁺ macrophages further promoted the proliferation and migration of Huh-7 cells. …”

Image 3_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tiff by Priscila Silva (556743)

“…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …”

Descriptive Statistics. by Sayed Jubair Bin Hossain (22430672)

“…Moreover, conflict-induced migration substantially augmented the incidence of hunger (IRR = 1.262; 95% CI: 1.111–1.435) and going without eating for an entire day (IRR = 1.251; 95% CI: 1.032–1.516), though international migration to Yemen decreased food insecurity. Additionally, being female, having higher education, and belonging to wealthier households were protective factors against food insecurity, while urban residence significantly increased the likelihood of hunger (IRR = 2.231; 95% CI: 1.990–2.501) and meal skipping (IRR = 3.657; 95% CI: 3.086–4.335).…”

Table 4_Integrated analysis of miRNAs-mRNAs in skeletal muscle development revealed that novel-miR-766 affects myoblast differentiation and myofiber-type formation in sheep.xlsx by Zhenzhen Gu (21488168)

“…In vitro assays revealed that myoblast differentiation and myotube formation were significantly inhibited by MYH3 knockdown via siMYH3 and that novel-miR-766 targets and decreases the expression of MYH3. …”

Data Sheet 2_Global burden of nasopharyngeal carcinoma attributable to alcohol use: a 1990–2021 analysis with projections to 2040.zip by Zhenyi Lu (22004786)

“…</p>Results<p>From 1990 to 2021, global ASMR declined from 0.31 to 0.19 per 100,000 population (AAPC −1.66; 95% CI −1.79 to −1.52) and ASDR fell with an AAPC of −1.72 (95% CI −1.87 to −1.57). Male ASMR decreased from 0.42 to 0.27 per 100,000 (AAPC −1.60), and female ASMR from 0.21 to 0.12 per 100,000 (AAPC −2.25). …”

Hypoxia response and tracheogenesis in <i>PGR</i> mutants. by Daiki Fujinaga (21301129)

“…Homozygous mutant pupae did not show significantly higher expression of <i>bnl</i> until 96 hours APF. …”

Table1_Causal association between inflammatory bowel disease and acute pancreatitis: a two-sample bidirectional mendelian randomization study.XLSX by Cong Zhang (582922)

“…Interestingly, AP was suggestively associated with a decreased risk of CD (OR = 0.797, 95% CI = 0.637-0.997, p = 0.047). …”

The Type I JAKinib, ruxolitinib, promotes pJAK1 and pJAK2 phosphorylation in MSCs from salivary glands. by Ilya Gurevic (1326786)

“…Error bars represent standard deviation; *p = 0.05; p = **** < 0.0001 represent the ANOVA-derived significance for the difference between all values. I = IFN.…”

Flexible Microfluidic Devices for Tunable Formation of Double Emulsion by Uditha Roshan (20841937)

“…This innovative approach significantly advances the field of droplet-based microfluidics, providing on-site, real-time tunability for the generation of double-emulsion droplets with high precision and reproducibility.…”

Table 2_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx by Rong Su (2210740)

“…In vitro, the overexpression of miR-4739 in Huh-7 cells significantly induced SPP1⁺ macrophages, and the culture medium derived from SPP1⁺ macrophages further promoted the proliferation and migration of Huh-7 cells. …”

Supplementary Material for: Hemispherotomy for Drug-Resistant Epilepsy in a Low-resource Setting: Surgical Outcomes and Quality of Life in 23 Children Treated in a Hybrid Program i... by figshare admin karger (2628495)

“…Patients with seizure freedom had significantly fewer preoperative seizures per day than patients with seizure recurrence. …”

Data Sheet 1_The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review.pdf by Thiago Henrique Teodoro (20703731)

“…</p>Conclusion<p>Chronic exercise decreases serum TNF-α and IL-6 levels, lowers the CD4/CD8 ratio, and increases IL-10 after 24 weeks, aiding Th1 and Th2 balance. …”

Supplementary file 1_Comparative analysis of accuracy and completeness in standardized database generation for complex multilingual lung cancer pathological reports: large language... by Hao Hang (7037264)

“…In English reports, it matched mainstream AI in lesion analysis (p > 0.05) but excelled in lymph node/pathology metrics (p < 0.05). Task load scores decreased by 38.3% post-implementation (413.90 ± 78.09 vs. 255.30 ± 65.50, t = 26.481, p < 0.001).…”

Data Sheet 1_Soy-based purified ingredient diet affects mouse gut permeability and the microbiome in fragile X mice.pdf by Cara J. Westmark (9302270)

“…Beta-diversity of the cecal microbiome was significantly altered as a function of the four test diets. …”

<b>Combination of isobavachalcone and amphotericin B has antifungal effect against </b><b>Cryptococcus neoformans</b><b>and protects host tissue damage by inhibiting ferroptosis</b... by Weidong Qian (20813608)

“…The results demonstrated that IBC (4 μg/mL) significantly reduced the minimum inhibitory concentration (MIC) of AmB from 1 μg/mL to 0.25 μg/mL, indicating a fourfold increase in potency. …”

Table 1_LncRNA NEAT1 promotes epithelial–mesenchymal transition in nasal polyp cells via the miR-199-3p/PAK4 axis.docx by Shuman Li (652613)

“…</p>Results<p>In comparison to controls, NEAT1 expression was significantly elevated in the epithelial tissues of CRSwNP. …”