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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
clinical decrease » clinical disease (Expand Search), clinical case (Expand Search), linear decrease (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
clinical decrease » clinical disease (Expand Search), clinical case (Expand Search), linear decrease (Expand Search)
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13361
Suppressing TLR4 alleviates cerebral injury in heatstroke rats through the modulation of microglial polarization
Published 2024“…<p dir="ltr"><b>Background:</b><b> </b>Heatstroke (HS) is a critical medical condition resulting from increased body temperatures, which can lead to significant damage to the central nervous system (CNS). …”
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13362
Supplementary file 1_Loss of SynDIG4/PRRT1 alters distribution of AMPA receptors in Rab4- and Rab11-positive endosomes and impairs basal AMPA receptor recycling.pdf
Published 2025“…We did not observe any change in baseline endocytosis; however, we did observe a significant decrease in recycling of GluA1-containing AMPARs in cultured hippocampal neurons from mice lacking SynDIG4. …”
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13363
Table 1_Association between cardiometabolic Index and obstructive sleep apnea and the mediating role of smoking: a cross-sectional study.docx
Published 2025“…Additionally, the findings from the threshold effects analysis indicate that maintaining CMI within an appropriate range can significantly decrease the likelihood of developing OSA.…”
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13364
Table1_Identification of key biomarkers and therapeutic targets in sepsis through coagulation-related gene expression and immune pathway analysis.docx
Published 2024“…<p>Sepsis, characterized by a widespread and dysregulated immune response to infection leading to organ dysfunction, presents significant challenges in diagnosis and treatment. In this study, we investigated 203 coagulation-related genes in sepsis patients to explore their roles in the disease. …”
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13365
Image 4_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.jpeg
Published 2025“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”
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13366
Data Sheet 1_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.pdf
Published 2025“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”
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13367
Supplementary file 8_Global burden of pancreatitis among individuals aged 15–39 years: a systematic analysis from the 2021 GBD study.docx
Published 2025“…Background<p>Pancreatitis represents a significant global public health challenge, yet there is a lack of comprehensive analyses focusing on the burden of pancreatitis and its long-term trends among young individuals aged 15–39 years.…”
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13368
Additional file 1 of Genome-wide association study of agronomic traits in winter wheat (Triticum aestivum L.) using a custom SNP marker set
Published 2025“…Additional file 9.xlsx Significant marker-trait associations.…”
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13369
Data Sheet 1_Effects of cattle manure and sludge vermicompost on nutrient dynamics and yield in strawberry cultivation with distinct continuous cropping histories in a greenhouse.d...
Published 2025“…In both substrate types, there was a substantial increase in microbial population and enzyme activity, accompanied by a significant decrease in phenolic acid content. During the senescence stage, the use of cattle manure vermicompost led to enhancements in plant height, leaf area, and root length, with increases ranging from 15.01% to 32.77% and 23.75% to 32.78% across the two substrate types compared to the control group. …”
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13370
Data Sheet 1_Giants in tourism: captive conditions, industry trends, and animal welfare implications for Asian elephants in tourism from 2014 to 2020.pdf
Published 2025“…There was a notable decrease in the frequency of venues offering elephant rides but a significant increase in other tourist experiences that allow direct visitor interaction with elephants, such as elephant washing and feeding. …”
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13371
Supplementary file 7_Global burden of pancreatitis among individuals aged 15–39 years: a systematic analysis from the 2021 GBD study.docx
Published 2025“…Background<p>Pancreatitis represents a significant global public health challenge, yet there is a lack of comprehensive analyses focusing on the burden of pancreatitis and its long-term trends among young individuals aged 15–39 years.…”
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13372
Table 1_Characteristics of myocardial work during exercise stress echocardiography in healthy adults.pdf
Published 2025“…</p>Results<p>GWI, GCW, and GWW increased, while GWE decreased after exercise. There were no significant differences in any of the global MW parameters between sexes at rest (all p > 0.05). …”
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13373
Data Sheet 1_Decadal changes in species composition of rare oak Quercus chungii forests with logging history.docx
Published 2024“…A larger contribution from balanced abundance variations than abundance gradient to the temporal β diversity suggested that there was no significant consistent increase or decrease in species abundance during this decade. …”
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13374
Supplementary file 6_Global burden of pancreatitis among individuals aged 15–39 years: a systematic analysis from the 2021 GBD study.docx
Published 2025“…Background<p>Pancreatitis represents a significant global public health challenge, yet there is a lack of comprehensive analyses focusing on the burden of pancreatitis and its long-term trends among young individuals aged 15–39 years.…”
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13375
Table 1_The burden and etiologies of diarrhea in Asia and its countries from 1990 to 2021 and the forecast to 2040: analyses informed by the global burden of disease study 2021.doc...
Published 2025“…The incidence and prevalence rates in 0–9 years old and 90+ years old and the DALY rates and mortality rates in all age groups in 2021 were decreased compared with 1990. Temporal joinpoint analysis revealed that after 2019, the age-standardized incidence rate (ASIR) of diarrhea exhibited a significant upward trend in Asia and some Asian countries. …”
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13376
Data Sheet 1_Emotional prompting amplifies disinformation generation in AI large language models.docx
Published 2025“…Impolite prompting resulted in a significant decrease in disinformation production across all models (davinci-002, 59%; davinci-003, 44%; and gpt-3.5-turbo, 28%) and a slight reduction for gpt-4 (94%).…”
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13377
Table 1_Global trends and stratified analysis of aortic aneurysm mortality: insights from the GBD 2021 study.docx
Published 2025“…The estimated annual percentage change in ASDR was −0.81 (95% CI: −0.95 to −0.66), and the average annual percentage change was −0.99 (95% CI: −1.07 to −0.90). Significant regional differences were observed, with high SDI regions experiencing a notable decrease in mortality rates, while low and low-middle SDI regions saw a substantial increase in deaths and an upward trend in mortality rates. …”
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13378
Table 1_The nonlinear relationship between estimated glomerular filtration rate and cardiovascular disease in US adults: a cross-sectional study from NHANES 2007–2018.docx
Published 2024“…Subgroup analyses revealed significant interactions for eGFR categories, anemia status, and ratio of family income to poverty (PIR).…”
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13379
Table 5_The burden and etiologies of diarrhea in Asia and its countries from 1990 to 2021 and the forecast to 2040: analyses informed by the global burden of disease study 2021.doc...
Published 2025“…The incidence and prevalence rates in 0–9 years old and 90+ years old and the DALY rates and mortality rates in all age groups in 2021 were decreased compared with 1990. Temporal joinpoint analysis revealed that after 2019, the age-standardized incidence rate (ASIR) of diarrhea exhibited a significant upward trend in Asia and some Asian countries. …”
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13380
Supplementary Material for: The impact of laparoscopic cystectomy for ovarian endometrioma on anti-Mullerian hormone levels: a systematic review and meta-analysis
Published 2025“…Primary outcomes showed a statistically significant (P < 0.001) decrease in anti-Müllerian hormone in the postoperative short-term period [-1.39 ng/mL, 95% CI, -2.01- (-0.76)], medium term period [-1.13 ng/mL (95% CI, -1.4- (-0.87)], and long term [-2.12 ng/mL (95% CI, -2.61- (-1.63)]. …”